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Hopkins gastroenterologists use endoscopic procedure to deliver therapeutic genes to the liver

Fixing or replacing faulty genes has emerged as a key to unlocking cures for numerous devastating diseases. But if the new, engineered genes can't find their way into the patient's genomic sequence, they won't help.

3 Oct 2018

Aggressive breast cancer hijacks normal protective physiological process to survive

A member of a protein family known for protecting our cells also protects cancer cells in aggressive, metastatic breast cancer, scientists report.

3 Oct 2018

CBT for insomnia may slow or reverse cortical atrophy in patients with co-morbid fibromyalgia

Preliminary findings from a pilot study suggest that cognitive behavioral therapy for insomnia may slow or even reverse the atrophy of cortical gray matter in patients who have co-morbid fibromyalgia.

3 Oct 2018

Specific details of PT interventions may be key determinants of knee replacement patient’s outcome

In an analysis of 112 records from 30 physical therapy sites regarding care for patients who had undergone total knee replacement surgery, investigators found that the content and amount of specific exercises varied widely.

3 Oct 2018

New portable medical devices allow real-time monitoring of therapy efficacy and pathology evolution

Thirteen new PhD students are embarking on a research journey in the area of microwave imaging this month, as part of the EU project EMERALD - ElectroMagnetic imaging for a novel genERation of medicAL Devices.

3 Oct 2018

Researchers for the first time differentiate human inner ear cells in laboratory

Researchers from the University of Bern and Bern University Hospital have managed for the first time to differentiate human inner ear cells in a laboratory from somatic progenitors and to investigate their origin.

3 Oct 2018

Carnegie professor receives NIH Director's New Innovator Award

Kathryn Whitehead, assistant professor of chemical engineering at Carnegie Mellon University, has been awarded a 2018 National Institutes of Health (NIH) Director's New Innovator Award for her project titled "Fate, Function, and Genetic Engineering of Breast Milk Cells for Infant Therapy."

3 Oct 2018

New tool can help researchers split and reassemble proteins

Researchers have developed a computational tool that makes it possible to split proteins and then restore them to functionality.

2 Oct 2018

Disruption in combination inhaled corticosteroid therapy may impact patients' symptoms and disease control

Disruption of the refill of patients' regular combination inhaled corticosteroid therapy brand may have impacted symptoms and disease control and potentially lead to an increased rate of costly exacerbations and hospitalizations.

2 Oct 2018

Study using DFMO shows positive results for children with high risk neuroblastoma

A paper published September 27 in Scientific Reports shows the positive results of a phase II clinical trial using the oral medication DFMO to prevent relapse in children with High Risk Neuroblastoma.

1 Oct 2018

Researchers caution that expediting HLH treatment may miss underlying cancers

Physicians who specialize in a devastating and aggressive immune disorder called hemophagocytic lymphohistiocytosis report in a new study that extra care should be taken to ensure an HLH diagnosis doesn't obscure possible underlying cancers.

1 Oct 2018

Elevated cerebrospinal fluid levels linked with autism diagnosis, third study confirms

Researchers at the UC Davis MIND Institute and the University of North Carolina have shown for the third time that an increased amount of extra-axial cerebrospinal fluid is associated with the diagnosis of autism spectrum disorder in young children.

1 Oct 2018

Philips introduces Ingenia Ambition X 1.5T MR with fully-sealed BlueSeal magnet for helium-free operations

Royal Philips, a global leader in health technology, today launched the Ingenia Ambition X 1.5T MR. Incorporating Philips’ breakthrough BlueSeal fully-sealed magnet, the Ingenia Ambition X is the world’s first MR system to enable helium-free operations, reducing the chance of potentially lengthy and costly disruptions, and virtually eliminating dependency on a commodity with an unpredictable supply.

From Philips Healthcare 1 Oct 2018

Why patients with ALL relapse after CAR-T cell therapy

Researchers have made a new discovery about a rare mechanism that triggers the relapse of acute lymphoblastic leukemia (ALL) after CAR T cell therapy.

1 Oct 2018

Why patients with ALL relapse after CAR-T cell therapy

Researchers have made a new discovery about a rare mechanism that triggers the relapse of acute lymphoblastic leukemia (ALL) after CAR T cell therapy.

1 Oct 2018

Phase 3 ECHELON-2 clinical trial evaluating ADCETRIS plus CHP meets primary endpoint

Seattle Genetics, Inc. and Takeda Pharmaceutical Company Limited announced today that the phase 3 ECHELON-2 clinical trial met its primary endpoint.

1 Oct 2018

TEAD1 protein appears to be important regulator of tumor migration in glioblastoma

A specific protein called TEAD1 is an important regulator of tumor migration in glioblastoma, the most common brain tumor in adults, and deactivating this protein may stop tumor cells from migrating away from the main tumor mass, according to research conducted at the Icahn School of Medicine at Mount Sinai and published October 1 in the journal Nature Communications.

1 Oct 2018

Therapy News and Research

Hopkins gastroenterologists use endoscopic procedure to deliver therapeutic genes to the liver

Aggressive breast cancer hijacks normal protective physiological process to survive

CBT for insomnia may slow or reverse cortical atrophy in patients with co-morbid fibromyalgia

Specific details of PT interventions may be key determinants of knee replacement patient’s outcome

New portable medical devices allow real-time monitoring of therapy efficacy and pathology evolution

Researchers for the first time differentiate human inner ear cells in laboratory

Carnegie professor receives NIH Director's New Innovator Award

New tool can help researchers split and reassemble proteins

Disruption in combination inhaled corticosteroid therapy may impact patients' symptoms and disease control

Study using DFMO shows positive results for children with high risk neuroblastoma

Researchers caution that expediting HLH treatment may miss underlying cancers

Elevated cerebrospinal fluid levels linked with autism diagnosis, third study confirms

Philips introduces Ingenia Ambition X 1.5T MR with fully-sealed BlueSeal magnet for helium-free operations

Why patients with ALL relapse after CAR-T cell therapy

Why patients with ALL relapse after CAR-T cell therapy

Phase 3 ECHELON-2 clinical trial evaluating ADCETRIS plus CHP meets primary endpoint

TEAD1 protein appears to be important regulator of tumor migration in glioblastoma

HyFly research project aims to break chains of infection and prevent pandemics

Gangrene-causing bacteria show promise as cancer treatment

New analysis confirms value of minimal residual disease as prognostic indicator in multiple myeloma

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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