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Mayo Clinic study reveals link between senescent cells and bone loss in mice

Mayo Clinic researchers have reported a causal link between senescent cells - the cells associated with aging and age-related disease - and bone loss in mice.

21 Aug 2017

Scientists discover novel therapeutic strategy to treat aggressive subgroup of lung cancer

Research conducted by a team of Norton Thoracic Institute scientists on a novel therapeutic avenue for an aggressive and difficult to treat subgroup of lung cancer was published in the August 15, 2017 issue of Cancer Research.

17 Aug 2017

Researchers discover way to stop deadly fungus from spreading to the brain

Research led by the University of Birmingham has discovered a way to stop a deadly fungus from 'hijacking' the body's immune system and spreading to the brain.

16 Aug 2017

Researchers develop and validate new assay that detects gene fusions in solid tumors

An assay that identifies a peculiar but important abnormality in cancer cells has been developed and validated by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

14 Aug 2017

Study provides promising framework to anticipate drug resistance in cancer

Being able to predict the resistance or sensitivity of a tumor cell to a drug is a key success-factor of cancer precision therapy.

14 Aug 2017

Biomedical scientist receives $1.83 million NIH grant for inflammatory bowel disease research

A biomedical scientist at the University of California, Riverside has received a $1.83 million grant to identify how the loss of a protective barrier in the intestine contributes to inflammatory bowel disease (IBD).

11 Aug 2017

TMDU-led researchers identify protein critical to early stages of cellular HIV infection

When a virus enters a cell, one of the first steps in the process of infecting that cell is removal of the protein coat that surrounds the virus's genetic material.

8 Aug 2017

Scientists stop formation of protein clumps linked to ALS and frontotemporal dementia

Scientists report in a new study that by imitating a natural process of cells, they prevented the formation of protein clumps associated with amyotrophic lateral sclerosis (ALS) and frontotemporal dementia.

8 Aug 2017

Researchers ferreting out patients most likely to become resistant to cancer treatment

According to the National Cancer Institute, the number of people beating a cancer diagnosis reached nearly 14.5 million in 2014 and is expected to rise to almost 19 million by 2024. Now, that's good news, but it doesn't mean that cancer researchers - in the lab or clinic - are resting on any laurels.

2 Aug 2017

Kinase-inactive BRAF mutation triggers lung adenocarcinoma development

The initiating oncogenic event in almost half of human lung adenocarcinomas is still unknown, a fact that complicates the development of selective targeted therapies.

2 Aug 2017

Neuro-oncology scientists discover unique molecular mechanism that maintains glioma stem cells

Glioblastoma is a primary brain tumor with dismal survival rates, even after treatment with surgery, chemotherapy, and radiation.

25 Jul 2017

Study seeks to understand genetic synergy in cleft palate

Like all of the individual elements of fetal development, palate growth is a marvel of nature. In part of this process, ledges of tissue on the sides of the face grow downwards on each side of the tongue, then upward, fusing at the midline at the top of the mouth.

19 Jul 2017

FDA approves first extended adjuvant therapy to lower risk of breast cancer recurrence

The U.S. Food and Drug Administration today approved Nerlynx (neratinib) for the extended adjuvant treatment of early-stage, HER2-positive breast cancer.

18 Jul 2017

Inhibition of cell receptors clears toxic proteins, cuts inflammation and improves cognition in animal models

Researchers have found cell receptors abnormally overexpressed in post-mortem brains of those with Parkinson's and Alzheimer's diseases, and that they can be inhibited in animal models to clear toxic protein buildup, reduce brain inflammation, and improve cognitive performance.

17 Jul 2017

Ground-breaking new breast cancer drugs have manageable toxicity profile for most patients

A ground-breaking new class of oral drugs for treating breast cancer, known as cyclin-dependent kinase (CDK) inhibitors, are generally well-tolerated, with a manageable toxicity profile for most patients.

13 Jul 2017

Scientists positively influence immune response in viral and bacterial co-infection

Researchers from Charité - Universitätsmedizin Berlin were able to positively influence the immune response in severe viral and bacterial co-infection.

13 Jul 2017

Novel approach to leukemia therapy can safely improve treatment success, reduce side effects

New University of Liverpool research, presented at an international conference, confirms that a novel approach to the treatment of chronic myeloid leukemia (CML) can safely increase treatment success and reduce negative side effects.

12 Jul 2017

Erectile dysfunction drug may be used to coat stents in future heart surgeries

Coating stents with an erectile dysfunction drug may be the way forwards in treating stent patients, say researchers.

12 Jul 2017

Researchers uncover novel mechanism of beta-blockers in preventing progression of heart failure

Beta-blocker drugs serve a key role in the treatment of heart failure, preventing bombardment of the heart by catecholamines - substances like epinephrine and norepinephrine - which overexcite and stress the heart.

4 Jul 2017

Memories stored in same neuron can be selectively erased, study suggests

Different types of memories stored in the same neuron of the marine snail Aplysia can be selectively erased, according to a new study by researchers at Columbia University Medical Center (CUMC) and McGill University and published today in Current Biology.

22 Jun 2017