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Mathematical model reveals the risk of SARS-CoV-2 infection after fecal microbiota transplantation

In their new paper available on the bioRxiv* preprint server, US researchers from the OpenBiome nonprofit organization used a mathematical model to simulate the usefulness of different testing strategies for fecal samples and showed that the probability of releasing a fecal microbiota donation with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is low when several important variables are taken into account.

28 Jun 2020

Towbin receives NIH grant to study modifier genes in cardiomyopathy

Jeffrey A. Towbin, MD, of Le Bonheur Children's Hospital and the University of Tennessee Health Science Center was awarded a Research Project Grant (R01) from the National Institutes of Health with co-principal investigators Enkhsaikha Purevjav, MD, PhD and Lu Lu, MD, MS.

26 Jun 2020

Groundbreaking experiment marks first successful delivery of mitochondria to liver cells

University of Connecticut researcher Dr. George Wu recently published a paper in the Journal of Gastroenterology and Hepatology outlining his successful experiment delivering mitochondria to liver cells.

25 Jun 2020

Promising treatment does not guard against complication in type 1 diabetes

Historically, half or more of people with type 1 diabetes develop kidney disease, which frequently progresses to kidney failure requiring hemodialysis or a kidney transplant for survival.

25 Jun 2020

Common food additive alters gut microbiota in mice

A common food additive, recently banned in France but allowed in the U.S. and many other countries, was found to significantly alter gut microbiota in mice, causing inflammation in the colon and changes in protein expression in the liver, according to research led by a University of Massachusetts Amherst food scientist.

25 Jun 2020

Whole genome sequencing can improve diagnosis and treatment of patients with rare diseases

A research programme pioneering the use of whole genome sequencing in the NHS has diagnosed hundreds of patients and discovered new genetic causes of disease.

24 Jun 2020

Male COVID-19 patients produce more SARS-CoV-2 antibodies than women

Health officials in the United Kingdom urge male coronavirus survivors to donate blood, particularly its convalescent plasma component. This comes after a new study has found that men produce more antibodies, which could make their plasma a valuable treatment against the coronavirus disease (COVID-19).

23 Jun 2020

HCV-positive organs can be safely used for transplantation, study shows

Patients who received a transplanted liver infected with hepatitis C and were later treated for the infection performed as well in recovery as transplant patients who received an organ free of infection, according to study from the University of Cincinnati College of Medicine and UC Health recently published in the journal Liver Transplantation.

22 Jun 2020

Tumor cell–based vaccine may prevent relapse of mantle cell lymphoma

A phase I/II clinical trial by researchers at Stanford University suggests that vaccines prepared from a patient's own tumor cells may prevent the incurable blood cancer mantle cell lymphoma (MCL) from returning after treatment.

22 Jun 2020

Scottish biotech Invizius seeks Series A funding for breakthrough in dialysis treatment

Scottish biotech firm Invizius, which has developed a technology aimed at reducing long-term side effects and health complications from dialysis treatment, is seeking Series A funding after undergoing promising safety trials.

22 Jun 2020

C-Path's Transplant Therapeutics Consortium receives positive FDA response for its Letter of Intent

Critical Path Institute announced today that its Transplant Therapeutics Consortium has received a positive response to its Letter of Intent from the U.S. Food and Drug Administration detailing the decision to accept the Composite Biomarker Panel (iBox Scoring System) into the Center for Drug Evaluation and Research (CDER) Biomarker Qualification Program.

17 Jun 2020

New test will help better manage patients with severe combined immunodeficiency

A new test developed at CHU Sainte-Justine in Montreal will enable better management of patients with severe combined immunodeficiency.

17 Jun 2020

Researchers call for caution of using CAR-T immunotherapy against AML

Acute myeloid leukemia is a hematological malignancy which incidence increases with age, that is biologically, phenotypically, and genetically very heterogeneous.

17 Jun 2020

Study investigates effectiveness of liver perfusion to improve the function of donor livers

A major study investigating the effectiveness of liver perfusion as a technique to improve the function of donor livers that would have otherwise been rejected has shown that up to 7 in every 10 could be used after just 4-6 hours of the assessment.

17 Jun 2020

Novel antisense drug shows promise to improve health of people with NAFLD

Using a first-of-its-class drug in a clinical trial, an international research effort headed by a scientist at University of California San Diego School of Medicine reports that inhibition of a key enzyme safely and effectively improved the health of persons with non-alcoholic fatty liver disease, a chronic metabolic disorder that affects hundreds of millions of people worldwide.

16 Jun 2020

Transplant News and Research

Mathematical model reveals the risk of SARS-CoV-2 infection after fecal microbiota transplantation

Towbin receives NIH grant to study modifier genes in cardiomyopathy

Groundbreaking experiment marks first successful delivery of mitochondria to liver cells

Promising treatment does not guard against complication in type 1 diabetes

Common food additive alters gut microbiota in mice

Whole genome sequencing can improve diagnosis and treatment of patients with rare diseases

Male COVID-19 patients produce more SARS-CoV-2 antibodies than women

HCV-positive organs can be safely used for transplantation, study shows

Tumor cell–based vaccine may prevent relapse of mantle cell lymphoma

Scottish biotech Invizius seeks Series A funding for breakthrough in dialysis treatment

C-Path's Transplant Therapeutics Consortium receives positive FDA response for its Letter of Intent

New test will help better manage patients with severe combined immunodeficiency

Researchers call for caution of using CAR-T immunotherapy against AML

Study investigates effectiveness of liver perfusion to improve the function of donor livers

Novel antisense drug shows promise to improve health of people with NAFLD

UCLA receives nearly $14 million NIH grant to investigate immunotherapy to destroy HIV

Cell signaling pathway could treat chronic kidney disease and other medical conditions

New model predicts patients’ likelihood of testing positive for COVID-19

A new technology to print 3D tissues directly in the body

Millimeter-thick cell-laden hydrogel fiber helps control blood glucose in diabetic mice

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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