in vivo News and Research

RSS

Lipid-peptide nanocomplexes offer new mRNA platform

A new paper reports the methodical development of lipid-peptide nanocomplexes as a delivery vehicle for messenger ribonucleic acid molecules to the tumor cell, in vitro and in vivo.

27 Jun 2022

COVID-19 can cause metabolism problems by interfering with insulin signaling, study reveals

It has become abundantly clear that coronavirus disease 19 (COVID-19), despite being transmitted by breathing in the SARS-CoV-2 virus, can have harmful effects far beyond the lungs.

27 Jun 2022

Study investigates the virological attributes of Omicron in a Syrian hamster model

Researchers investigated the virological attributes of SARS‐CoV‐2 new variant of concern Omicron in a Syrian hamster model.

27 Jun 2022

Bisphosphonates appear to improve COVID-19 exposure outcomes

A new retrospective study examines the effect of bisphosphonates on COVID-19 outcomes.

27 Jun 2022

Fragment crystallizable-altered COVID-19 antibodies efficacious across two animal models

A recent article posted to the bioRxiv* preprint server identified numerous efficacious severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies from convalescent SARS-CoV-2 patients.

23 Jun 2022

Mutation in SARS-CoV-2 nucleocapsid protein found to enhance replication and pathogenicity

Researchers investigated a highly variable region at residues 203 to 205 in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleocapsid (N) protein.

23 Jun 2022

Kratom: A dangerous or beneficial plant?

A new study summarizes the traditional and modern uses of kratom, as well as its pharmacology, benefits, and adverse health impacts.

23 Jun 2022

Preclinical study unlocks the promise of CAR T-cell therapy for treatment of solid tumors

Scientists at St. Jude Children's Research Hospital identified a molecular mechanism that in a preclinical study unlocked the promise of CAR T–cell therapy for treatment of solid tumors.

22 Jun 2022

Researchers map cancer driver mutations across the human genome

In a recent study published in Nature Biotechnology, researchers explored the causes of cancer by mapping somatic mutation rates across the human genome.

22 Jun 2022

Potential SARS-CoV-2 antivirals based on host miRNAs

A recent research paper posted to the bioRxiv* preprint server demonstrated micro ribonucleic acids (miRNAs) as potential antiviral options against various coronaviruses (CoVs), including severe acute respiratory syndrome CoV 2 (SARS-CoV-2).

21 Jun 2022

Wistar scientists discover a new way to boost a person's immune response to tumors

Due to the development of resistance to chemotherapy and recurring tumors, patients with ovarian cancer often have low survival rates.

21 Jun 2022

Cannabis consumption may relieve fatigue according to new study

Investigators recently analyzed the impacts of Cannabis flower consumption in the treatment of fatigue

20 Jun 2022

Multifunctional nanoparticle system may be a promising therapeutic way for breast cancer therapy

In this new article publication from Acta Pharmaceutica Sinica B, authors Yun Yang, Danrong Hu, Yi Lu, Bingyang Chu, Xinlong He, Yu Chen, Yao Xiao, Chengli Yang, Kai Zhou, Liping Yuan and Zhiyong Qian from Sichuan University, Chengdu discuss tumor-targeted/reduction-triggered composite multifunctional nanoparticles for breast cancer chemo-photothermal combinational therapy.

18 Jun 2022

Study points to a new direction for the development of NAMPT-targeted cancer therapies

In this new article publication from Acta Pharmaceutica Sinica B, authors Ying Wu, Congying Pu, Yixian Fu, Guoqiang Dong, Min Huang and Chunquan Sheng from Second Military Medical University, Shanghai, China and University of Chinese Academy of Sciences, Shanghai, China discuss how NAMPT-targeting PROTAC promotes antitumor immunity via suppressing myeloid-derived suppressor cell expansion.

18 Jun 2022

Nanoparticles may be the next-generation solution for teeth whitening

Researchers reviewed nanoparticles (NPs) as next-generation whitening agents for teeth.

17 Jun 2022

AI method automatically detects plaque erosion in the heart's arteries based on OCT images

Researchers have developed a new artificial intelligence (AI) method that can automatically detect plaque erosion in the heart's arteries using optical coherence tomography (OCT) images.

16 Jun 2022

First-of-its-kind technology repairs and regenerates heart muscle cells

Researchers at the University of Houston are reporting a first-of-its-kind technology that not only repairs heart muscle cells in mice but also regenerates them following a heart attack, or myocardial infarction as its medically known.

16 Jun 2022

NSP1 found to act as an immune evasion factor in SARS-CoV-2 infections

A new study explores the role of non-structural protein 1 (NSP1) in SARS-CoV-2 infection and pathogenesis.

16 Jun 2022

Fc-effector functions for selecting COVID-19 convalescent plasma

In a recent study posted to the bioRxiv* preprint server, researchers demonstrated that coronavirus disease 2019 (COVID-19) convalescent plasmas (CCPs) with low neutralizing and high fragment crystallizable (Fc)-effector activity result in effective prophylaxis.

15 Jun 2022

Two broadly neutralizing antibodies show promise to provide long-acting immunity against SARS-CoV-2

Two broadly neutralizing antibodies show great promise to provide long-acting immunity against COVID-19 in immunocompromised populations according to a paper published June 15 in the Journal of Experimental Medicine (JEM).

15 Jun 2022

in vivo News and Research

Lipid-peptide nanocomplexes offer new mRNA platform

COVID-19 can cause metabolism problems by interfering with insulin signaling, study reveals

Study investigates the virological attributes of Omicron in a Syrian hamster model

Bisphosphonates appear to improve COVID-19 exposure outcomes

Fragment crystallizable-altered COVID-19 antibodies efficacious across two animal models

Mutation in SARS-CoV-2 nucleocapsid protein found to enhance replication and pathogenicity

Kratom: A dangerous or beneficial plant?

Preclinical study unlocks the promise of CAR T-cell therapy for treatment of solid tumors

Researchers map cancer driver mutations across the human genome

Potential SARS-CoV-2 antivirals based on host miRNAs

Wistar scientists discover a new way to boost a person's immune response to tumors

Cannabis consumption may relieve fatigue according to new study

Multifunctional nanoparticle system may be a promising therapeutic way for breast cancer therapy

Study points to a new direction for the development of NAMPT-targeted cancer therapies

Nanoparticles may be the next-generation solution for teeth whitening

AI method automatically detects plaque erosion in the heart's arteries based on OCT images

First-of-its-kind technology repairs and regenerates heart muscle cells

NSP1 found to act as an immune evasion factor in SARS-CoV-2 infections

Fc-effector functions for selecting COVID-19 convalescent plasma

Two broadly neutralizing antibodies show promise to provide long-acting immunity against SARS-CoV-2

eBook: Using iPSCs models for human disease research and drug discovery eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Latest News