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Combining a chemical blocker of immune cell exit with immunotherapy stops skin cancer growth

The number of specialized immune cells available for fighting skin cancer doubled when a new treatment blocked their escape from melanoma tumors, experiments in mice and human cells show.

27 Feb 2023

Innate lymphoid cells educate alveolar macrophages following exposure to different viruses

A study conducted by researchers at the University of Liège on group 2 innate lymphoid cells (or ILC2s) shows that the functional reprogramming of these cells following their exposure to viruses allows our body to react differently to exposure to certain respiratory allergens.

27 Feb 2023

Study: Half of adverse pregnancy outcomes occur in individuals without any heart disease risk factors

Many pregnancy complications are associated with future heart disease. Such complications include gestational diabetes, preterm birth, fetal growth restriction and hypertensive disorders of pregnancy (gestational hypertension, preeclampsia and related disorders), and together they are referred to as adverse pregnancy outcomes (APOs).

27 Feb 2023

Readers and tweeters urgently plea for a proper ‘role’ call in the ER

The story of one patient’s ER experience does not at all capture the complexities of an emergency department serving the needs of a stochastic patient population.

27 Feb 2023

Dementia care programs help, if caregivers can find them

There's no cure, yet, for Alzheimer's disease. But dozens of programs developed in the past 20 years can improve the lives of both people living with dementia and their caregivers.

27 Feb 2023

Study shows COVID-19 rates were likely forty-times higher than CDC estimates during BA.4/BA.5 dominant period in the U.S.

Researchers evaluate the prevalence of SARS-CoV-2 infections and the incidence of long COVID during BA.4/BA.5 dominant period.

27 Feb 2023

Rebounding of COVID-19 symptoms and viral load are common among untreated COVID-19 patients

Researchers characterize COVID-19 symptom and viral load rebounds among untreated individuals with mild-to-moderate SARS-CoV-2 infection.

27 Feb 2023

Cannabis users have higher complexity of co-existing conditions

As legislation in multiple states eases former restrictions around medical and recreational cannabis in the United States, an increasing proportion of the population reports use of the drug. Between 2016 and 2018, more than 22 percent of Massachusetts residents reported any prior cannabis use for medical or recreational reasons. However, little is known about cannabis use in patients who undergo surgery or interventional procedures, where cannabis use has important additional clinical implications.

27 Feb 2023

Determining the role of the epigenetic enzyme, HDAC5, in an animal model

Substance use disorder (SUD) is an extremely difficult disorder to overcome, and many individuals with SUD return to regular use after repeated attempts to quit.

27 Feb 2023

Novel software tool helps analyze animal behaviors

A team from the University of Michigan has developed a new software tool to help researchers across the life sciences more efficiently analyze animal behaviors.

25 Feb 2023

TTUHSC El Paso collaborates with Doctors of the World USA to launch the Border Health Program

The large influx of migrants and asylum seekers crossing the U.S.-Mexico border in the El Paso area has also resulted in a spike of medical emergencies.

25 Feb 2023

Viable treatment option for patients with advanced cervical cancer

A recent University of Kentucky Markey Cancer Center study suggests a new radiopharmaceutical compound may be a viable treatment option for patients with advanced cervical cancer.

25 Feb 2023

Significance of mathematical modeling in understanding complex biological processes

Humans and animals detect different stimuli such as light, sound, and odor through nerve cells, which then transmit the information to the brain. Nerve cells must be able to adjust to the wide range of stimuli they receive, which can range from very weak to very strong. To do this, they may become more or less sensitive to stimuli (sensitization and habituation), or they may become more sensitive to weaker stimuli and less sensitive to stronger stimuli for better overall responsiveness (gain control). However, the exact way this happens is not yet understood.

25 Feb 2023

Simplifying the analysis of social contacts using novel computational method

How society organizes affects different phenomena, from the transmission of information to the spread of contagious diseases. The more links we establish with each other via social and transportation networks, the more spread is favored. To study the dynamics of complex systems, such as society, we can infer these networks – in which nodes, representing individuals, connect through lines – from real-world data. However, these networks are usually large, dense, and cumbersome to manipulate.

25 Feb 2023

Virus encounter educates human immune system, says study

25 Feb 2023

Novel microfluidic model mimics a rare genetic disorder

Our bodies are made up of 60,000 miles of complex pipes that play a vital role in transporting nutrients throughout our bodies, performing waste disposal, and supplying our organs with fresh oxygen and blood.

24 Feb 2023

Study findings likely to guide the design of engineered TAPBPR variants with tailored HLA specificity

Researchers at Children's Hospital of Philadelphia (CHOP) have identified variants of a chaperone molecule that optimizes the binding and presentation of foreign antigens across the human population, which could open the door to numerous applications where robust presentation to the immune system is important, including cell therapy and immunization. The findings were published today in Science Advances.

24 Feb 2023

Study investigates patients' perspectives on use of race-based algorithms in clinical decision-making

Algorithms that incorporate race as a modifying factor to guide clinical decision-making have recently been criticized for propagating racial bias in medicine.

24 Feb 2023

Difference between human and mouse lung tumor cells explains the discrepancy in cancer drug results

A small but significant metabolic difference between human and mouse lung tumor cells, has been discovered by Weill Cornell Medicine researchers, explaining a discrepancy in previous study results, and pointing toward new strategies for developing cancer treatments.

24 Feb 2023

Organoid models for research on Chinese herbal medicine

Announcing a new publication for Acta Materia Medica journal. Organoids are three-dimensional cell accusations generated from pluripotent stem cells or adult stem cells in vitro.

24 Feb 2023

Medicine News and Research

Combining a chemical blocker of immune cell exit with immunotherapy stops skin cancer growth

Innate lymphoid cells educate alveolar macrophages following exposure to different viruses

Study: Half of adverse pregnancy outcomes occur in individuals without any heart disease risk factors

Readers and tweeters urgently plea for a proper ‘role’ call in the ER

Dementia care programs help, if caregivers can find them

Study shows COVID-19 rates were likely forty-times higher than CDC estimates during BA.4/BA.5 dominant period in the U.S.

Rebounding of COVID-19 symptoms and viral load are common among untreated COVID-19 patients

Cannabis users have higher complexity of co-existing conditions

Determining the role of the epigenetic enzyme, HDAC5, in an animal model

Novel software tool helps analyze animal behaviors

TTUHSC El Paso collaborates with Doctors of the World USA to launch the Border Health Program

Viable treatment option for patients with advanced cervical cancer

Significance of mathematical modeling in understanding complex biological processes

Simplifying the analysis of social contacts using novel computational method

Virus encounter educates human immune system, says study

Novel microfluidic model mimics a rare genetic disorder

Study findings likely to guide the design of engineered TAPBPR variants with tailored HLA specificity

Study investigates patients' perspectives on use of race-based algorithms in clinical decision-making

Difference between human and mouse lung tumor cells explains the discrepancy in cancer drug results

Organoid models for research on Chinese herbal medicine

Everything there is to know about biosimilars eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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