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Dog study suggests that AAV in gene therapy could induce cancer

A gene therapy study in dogs has stirred up old fears that by using AAV in gene therapy, it may be increasing cancer chances.

8 Jan 2020

Bacterial exposure is a potential environmental risk factor in developing coeliac disease

Bacterial exposure has been identified as a potential environmental risk factor in developing coeliac disease, a hereditary autoimmune-like condition that affects about one in 70 Australians.

8 Jan 2020

Study reveals new mechanism that controls the causes of stomach disease

Infectious diseases triggered by bacteria and other microbes are the most frequent cause of human mortality across the globe.

8 Jan 2020

Cornell study details role of stem cell in deadly gastric cancer

A Cornell study provides important new insights into a common and deadly type of gastric cancer.

7 Jan 2020

Major genetic study provides most comprehensive map of breast cancer risk variants to date

A major international study of the genetics of breast cancer has identified more than 350 DNA 'errors' that increase an individual's risk of developing the disease. The scientists involved say these errors may influence as many as 190 genes.

7 Jan 2020

Classroom activities pose low risk of harmful gluten exposure in children with celiac disease

Common classroom activities – such as playing with Play-Doh or uncooked pasta – have little or no potential to cause harmful gluten exposure in children with celiac disease, reports a study in the Journal of Pediatric Gastroenterology and Nutrition.

7 Jan 2020

Novel computer algorithm identifies promising new treatment for neuroblastoma

Using a computer algorithm, scientists at Uppsala University have identified a promising new treatment for neuroblastoma.

7 Jan 2020

New drug compounds thwart master regulator of tumor growth, metastasis

Scientists have developed new drug compounds that thwart the pro-cancer activity of FOXM1, a transcription factor that regulates the activity of dozens of genes.

7 Jan 2020

Novel nanoparticle vaccine provides long-lasting protection against influenza virus

A novel nanoparticle vaccine that combines two major influenza proteins is effective in providing broad, long-lasting protection against influenza virus in mice, showing promise as a universal flu vaccine, according to a study by the Institute for Biomedical Sciences at Georgia State University.

7 Jan 2020

AI Therapeutics reports considerable progress on LAM-001 and LAM-004 clinical trials

AI Therapeutics is a clinical-stage biopharmaceutical company that has created an artificial intelligence-driven drug development platform for matching drugs to new indications.

7 Jan 2020

Some genetic sequencing misses out large parts of the genome

A study of patient samples has found that more than a quarter of genes are missed in genetic sequencing procedures.

7 Jan 2020

Discovery could pave way for new breast cancer drugs

Eric Prossnitz, PhD, hopes to help many of the 12% of American women who are projected to be diagnosed with breast cancer in their lifetimes.

7 Jan 2020

Boehringer Ingelheim to use PhoreMost's SITESEEKER platform in new collaboration

PhoreMost to deploy its SITESEEKER platform to identify novel targets for Boehringer Ingelheim’s discovery programs.

From PhoreMost 7 Jan 2020

New antibody-drug conjugate shows promising activity in salivary gland tumors

The antibody-drug conjugate ado-trastuzumab emtansine (T-DM1) has promising activity in HER2 amplified salivary gland tumors, according to data published in the Annals of Oncology.

7 Jan 2020

New molecular mechanism can reverse genetic defect responsible for Friedreich's ataxia

Scientists at Tufts University have identified a molecular mechanism that could reverse the genetic defect responsible for Friedreich's ataxia, a neurodegenerative disease that leaves its victims with difficulty walking, a loss of sensation in the arms and legs and impaired speech caused by degeneration of nerve tissue in the spinal cord.

6 Jan 2020

Study shows safety, long-term beneficial impact of gene therapy for patients with Hemophilia A

A breakthrough gene therapy treatment for Haemophilia A has been shown to offer long-term benefits that have already transformed the lives of 13 men in the UK.

6 Jan 2020

New clinical study to test retinal screening processes for early detection of Alzheimer's disease

The University of Rhode Island, in collaboration with BayCare Health System in Florida and The Memory and Aging Program at Butler Hospital, an affiliate of The Warren Alpert Medical School of Brown University, is launching a clinical trial of retinal screening processes that could help clinicians detect Alzheimer's disease possibly two or more decades before patients develop life-altering clinical symptoms.

6 Jan 2020

New blood test can help identify elderly concussion patients with brain tissue damage

Novel research shows that a blood test can differentiate elderly concussion patients with brain tissue damage from those without it. This finding, published in the special brain health collection of AACC's The Journal of Applied Laboratory Medicine, could help ensure that elderly patients with severe concussions receive crucial treatment for their injuries.

6 Jan 2020

Body clock gene impairs defense against pneumonia

Most living things have an internal body clock which regulates when they sleep and when they wake up. A complex set of genes turning on and off, make this body clock run over roughly 24 hours, and a gene known by the acronym BMAL1 is one of the master regulators of this clock, controlling many other body clock genes and pathways.

6 Jan 2020

Discovery of cellular 'hands' could have implications in the fields of cell, developmental biology

The protein, called syndecan-4, combines with fellow cell membrane proteins, called integrins, to form protruding 'hands' that sense the environment outside the cell.

6 Jan 2020

Protein C News and Research

Dog study suggests that AAV in gene therapy could induce cancer

Bacterial exposure is a potential environmental risk factor in developing coeliac disease

Study reveals new mechanism that controls the causes of stomach disease

Cornell study details role of stem cell in deadly gastric cancer

Major genetic study provides most comprehensive map of breast cancer risk variants to date

Classroom activities pose low risk of harmful gluten exposure in children with celiac disease

Novel computer algorithm identifies promising new treatment for neuroblastoma

New drug compounds thwart master regulator of tumor growth, metastasis

Novel nanoparticle vaccine provides long-lasting protection against influenza virus

AI Therapeutics reports considerable progress on LAM-001 and LAM-004 clinical trials

Some genetic sequencing misses out large parts of the genome

Discovery could pave way for new breast cancer drugs

Boehringer Ingelheim to use PhoreMost's SITESEEKER platform in new collaboration

New antibody-drug conjugate shows promising activity in salivary gland tumors

New molecular mechanism can reverse genetic defect responsible for Friedreich's ataxia

Study shows safety, long-term beneficial impact of gene therapy for patients with Hemophilia A

New clinical study to test retinal screening processes for early detection of Alzheimer's disease

New blood test can help identify elderly concussion patients with brain tissue damage

Body clock gene impairs defense against pneumonia

Discovery of cellular 'hands' could have implications in the fields of cell, developmental biology

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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