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AmpliPhi receives positive feedback from FDA for its AB-PA01 product targeting P.aeruginosa infections

AmpliPhi Biosciences Corporation, a clinical-stage biotechnology company focused on precisely targeted bacteriophage therapeutics for antibiotic-resistant infections, today announced that the company has received positive feedback, via written response, from the U.S. Food and Drug Administration regarding its development plans for AB-PA01, without the need for a Type B Pre-IND meeting.

19 Sep 2018

Surprising research showing peptide adaptability may pave way to develop immunotherapies

The body's immune system is a valiant weapon against disease, and harnessing its power through a technique called immunotherapy is at the forefront of current research to treat cancer and other diseases.

19 Sep 2018

Researchers use CRISPR screen to reveal new targets in squamous cell carcinomas

A little p63 goes a long way in embryonic development - and flaws in p63 can result in birth defects like cleft palette, fused fingers or even missing limbs.

18 Sep 2018

Use of transcranial electrical stimulation to bolster creativity has far-reaching implications

What is creativity, and can it be enhanced -- safely -- in a person who needs a boost of imagination? Georgetown experts debate the growing use of electrical devices that stimulate brain tissue, and conclude there is potential value in the technique. However, use of these machines also raises neuro-ethical, legal, and social issues that must now be addressed.

18 Sep 2018

Microbiota in the intestines and cell stress cause colon cancer

"With our study we originally wanted to study the role of bacteria in the intestines in the development of intestinal inflammation," explains Professor Dirk Haller from the Department of Nutrition and Immunology at the Weihenstephan Science Centre of the TUM.

18 Sep 2018

Human brains may be wired to prefer lying on the couch, suggests research

If getting to the gym seems like a struggle, a University of British Columbia researcher wants you to know this: the struggle is real, and it's happening inside your brain.

18 Sep 2018

Logos Biosystems releases new electrophoretic tissue clearing system with twice the features in half the space

Logos Biosystems has released the latest system for electrophoretic tissue clearing, the X-CLARITY™ Tissue Clearing System II. The new system has been upgraded with new features that make it streamlined, easier to use and more intuitive.

From Logos Biosystems 18 Sep 2018

Purifying Proteins from Mammalian Cell Culture

In many cases mammalian cells are the only option to produce recombinant proteins with correct post-translational modifications, e.g. glycosylation, which are required for proper function of the therapeutic protein.

From Sartorius 18 Sep 2018

Outcome of ACL reconstruction related to the way you move post-surgery

A third of people who undergo ACL reconstruction surgery will have osteoarthritis in their injured knee within 10 years. Within two decades, nearly 50 percent will -- terrible odds for getting a debilitating condition with no known cure.

18 Sep 2018

Targeted Lung Denervation procedure significantly reduces COPD problems

First results from a clinical trial of a procedure to open obstructed airways in patients with chronic obstructive pulmonary disease have shown that it significantly reduces problems associated with the disease and is safe.

18 Sep 2018

More women veterans with chronic pain use CIH therapies than men

A recent major shift in practice by the Veterans Health Administration now means that complementary and integrative health therapies such as meditation, yoga and acupuncture are increasingly being offered to VA patients as non-drug approaches for pain management and related conditions, says Elizabeth Evans, an epidemiology researcher in the School of Public Health and Health Sciences at the University of Massachusetts Amherst.

18 Sep 2018

Sleep apnea, congenital heart disease in hospitalized infants strongly associated with death

Infants often aren't screened for sleep apnea, but a new study suggests the disorder may be tied to an increased risk of death in infants with congenital heart disease.

17 Sep 2018

People battling substance use disorders may benefit from meth-relapse prevention compound

New research raises the possibility that a wider group of people battling substance use disorders may benefit from a Scripps Research-developed relapse-prevention compound than previously thought.

17 Sep 2018

Concussion symptoms last for longer time in kids than adults

Concussion symptoms for children under 13 years old typically last three times longer than they do for older teens and adults, but keeping them out of the classroom during recovery is not necessarily the preferred treatment, according to a comprehensive research review in The Journal of the American Osteopathic Association.

17 Sep 2018

Promising gene therapy for 'day blind' sheep now safe for clinical trials in human patients

Back in 2009, a group of Israeli researchers identified a herd of Awassi sheep suffering from "day blindness". As its name implies, these sheep were blind during the day (in bright light) but could see at night, in low-light conditions.

17 Sep 2018

Boehringer Ingelheim announces study results of COPD patients treated with Spiolto Respimat

Boehringer Ingelheim announced results from the OTIVACTO study, an observational European real-world study of 7,443 Chronic Obstructive Pulmonary Disease patients treated with Spiolto Respimat, which were presented today at the European Respiratory Society International Congress 2018 in Paris, France

17 Sep 2018

New Medicare Advantage tool to lower drug prices puts crimp in patients’ choices

Starting next year, Medicare Advantage plans will be able to add restrictions on expensive, injectable drugs administered by doctors to treat cancer, rheumatoid arthritis, macular degeneration and other serious diseases.

17 Sep 2018

Inhaled steroid use linked to greater risk of NTM lung infections

Patients using inhaled steroids to control asthma and other breathing problems may be at greater risk for developing nontuberculous mycobacteria lung infections, according to new research published online in the Annals of the American Thoracic Society.

17 Sep 2018

Adding PET scans to CT imaging can change treatment for women with cervical cancer

An Ontario clinical study that shows adding PET imaging to conventional CT imaging to stage locally advanced cervix cancer can change treatment means newly diagnosed women in this province may also receive PET imaging.

17 Sep 2018

Solution-focused communication by nurses improves control of liquid intake during hemodialysis

The research was conducted over a period of six months with a group of 36 patients in the Hemodialysis Unit of the General University Hospital of Alicante and three nurses who had received training in solution-focused communication.

17 Sep 2018

Therapy News and Research

AmpliPhi receives positive feedback from FDA for its AB-PA01 product targeting P.aeruginosa infections

Surprising research showing peptide adaptability may pave way to develop immunotherapies

Researchers use CRISPR screen to reveal new targets in squamous cell carcinomas

Use of transcranial electrical stimulation to bolster creativity has far-reaching implications

Microbiota in the intestines and cell stress cause colon cancer

Human brains may be wired to prefer lying on the couch, suggests research

Logos Biosystems releases new electrophoretic tissue clearing system with twice the features in half the space

Purifying Proteins from Mammalian Cell Culture

Outcome of ACL reconstruction related to the way you move post-surgery

Targeted Lung Denervation procedure significantly reduces COPD problems

More women veterans with chronic pain use CIH therapies than men

Sleep apnea, congenital heart disease in hospitalized infants strongly associated with death

People battling substance use disorders may benefit from meth-relapse prevention compound

Concussion symptoms last for longer time in kids than adults

Promising gene therapy for 'day blind' sheep now safe for clinical trials in human patients

Boehringer Ingelheim announces study results of COPD patients treated with Spiolto Respimat

New Medicare Advantage tool to lower drug prices puts crimp in patients’ choices

Inhaled steroid use linked to greater risk of NTM lung infections

Adding PET scans to CT imaging can change treatment for women with cervical cancer

Solution-focused communication by nurses improves control of liquid intake during hemodialysis

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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