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The impact of specific comorbidities and overall multimorbidity on the three mechanistically distinct phases of COVID-19

Researchers studied the impact of comorbidities in the three distinct phases of COVID-19.

21 Feb 2023

Adverse muscle composition can predict mortality risk in people with fatty liver disease

Obesity and a sedentary lifestyle contribute to an increasing number of people developing fatty liver disease.

21 Feb 2023

Simple blood tests for telomeric protein could provide a valuable screen for certain cancers

Once thought incapable of encoding proteins due to their simple monotonous repetitions of DNA, tiny telomeres at the tips of our chromosomes seem to hold a potent biological function that's potentially relevant to our understanding of cancer and aging.

21 Feb 2023

Adipose-targeted delivery of thyroid hormone alleviates hypercholesterolemia and atherosclerosis

A research team from LKS Faculty of Medicine, the University of Hong Kong (HKUMed) has developed thyroid hormone (TH) - encapsulated nanoparticles modified with adipose-homing peptide, which selectively transport TH to adipose tissues.

20 Feb 2023

Use of dapivirine vaginal ring during third trimester of pregnancy poses no safety concerns

A vaginal ring containing the antiretroviral drug dapivirine posed no safety concerns when used in the third trimester of pregnancy, according to results to date from the first study of the dapivirine ring during pregnancy and one of only a few studies of an HIV prevention product in pregnant cisgender women.

20 Feb 2023

Structure of DREADD designer receptor could pave the way for creating next generation tools

In order to more fully understand how diseases arise in the brain, scientists must unravel the intricate way neurons relay messages (either chemical or electrical) along a complex web of nerve cells.

20 Feb 2023

Research reveals regional differences in the spread of Japan's two main ancestral groups

Regional differences in the spread of Japan's two main ancestral groups have been revealed, thanks to new research at the University of Tokyo.

20 Feb 2023

Brexanolone inhibits key systemic inflammatory pathways associated with post-partum depression

Post-partum depression (PPD) develops after childbirth and affects both the mother's and the infant's health by preventing healthy bonding.

20 Feb 2023

Doxycycline taken after sex does not prevent bacterial STIs among cisgender women

Researchers from the University of Washington (UW), Kenya Medical Research Institute (KEMRI), and Hennepin Healthcare Research Institute (HHRI) announced results at CROI from a clinical trial demonstrating that doxycycline taken after sex does not prevent bacterial sexually transmitted infections (STIs) – chlamydia or gonorrhea – among cisgender women.

20 Feb 2023

Ketamine appears to hold promise in treating cocaine-use disorders

As cocaine use continues to climb across the United States, scientists have struggled to develop an effective pharmacological approach to treat the devastating disorder.

20 Feb 2023

Spinal cord stimulation technology instantly improves arm and hand mobility in stroke patients

A neurotechnology that stimulates the spinal cord instantly improves arm and hand mobility, enabling people affected by moderate to severe stroke to conduct their normal daily activities more easily, report researchers from the University of Pittsburgh and Carnegie Mellon University today in Nature Medicine.

20 Feb 2023

E-cigarettes as a first-line aid for smoking cessation in adults

Should electronic cigarettes, or vapes, be accepted more widely as an effective and respected tool for treating adult smokers’ nicotine addiction?

20 Feb 2023

COVID-19 vaccination associated with fewer heart attacks, strokes, and other cardiovascular issues

Analyzing the most extensive datasets in the United States, researchers from the Icahn School of Medicine at Mount Sinai have revealed that vaccination against COVID-19 is associated with fewer heart attacks, strokes, and other cardiovascular issues among people who were infected with SARS-CoV-2, the virus that causes COVID-19.

20 Feb 2023

Activating or deactivating drugs with the help of light

Scientists at the Paul Scherrer Institute PSI have used the Swiss X-ray free-electron laser SwissFEL and the Swiss Light Source SLS to make a film that could give a decisive boost to developing a new type of drug.

20 Feb 2023

Some parents may not be properly responding to elevated temperatures in children, poll suggests

For many children, winter season comes with regular exposure to circulating viruses at school or daycare. And a warm forehead is often one of the first clear signs a child has caught a bug.

20 Feb 2023

Utilizing CRISPR to discover new therapy options for COPD

In this interview, we speak to Ceri Wiggins, a Director at AstraZeneca, about the many applications of CRISPR and its role in discovering new COPD therapies.

From Society for Laboratory Automation and Screening (SLAS) 20 Feb 2023

Genome editing prevents hypertrophic cardiomyopathy in mice

In a recent study published in the journal PLoS Digital Health, researchers pursued one-time cures for hypertrophic cardiomyopathy (HCM). They used a previously constructed murine model of HCM, designated as R403Q-129SvEv, to evaluate two different genetic therapies, as follows:

19 Feb 2023

UTHSC researchers secure $308,000 grant from Department of Defense for dementia study

Repeated traumatic brain injuries (TBI) in soldiers and military personnel can cause behavioral, neurological, and cognitive effects and lead to dementia.

19 Feb 2023

Toxic protein may be the cause of muscular dystrophy and arhinia

Balancing care responsibilities with paid work provides working caregivers with emotional benefits

19 Feb 2023

Proposal to scrap England’s long term plan for cancer could cost lives, experts warn

The UK government's proposal to roll England's long term plan for cancer into one strategy covering all major conditions, such as cardiovascular disease, chronic respiratory disease, dementia, mental health conditions, and musculoskeletal disorders is "a catastrophic decision that will cost lives," warn experts in The BMJ today.

17 Feb 2023

Medicine News and Research

The impact of specific comorbidities and overall multimorbidity on the three mechanistically distinct phases of COVID-19

Adverse muscle composition can predict mortality risk in people with fatty liver disease

Simple blood tests for telomeric protein could provide a valuable screen for certain cancers

Adipose-targeted delivery of thyroid hormone alleviates hypercholesterolemia and atherosclerosis

Use of dapivirine vaginal ring during third trimester of pregnancy poses no safety concerns

Structure of DREADD designer receptor could pave the way for creating next generation tools

Research reveals regional differences in the spread of Japan's two main ancestral groups

Brexanolone inhibits key systemic inflammatory pathways associated with post-partum depression

Doxycycline taken after sex does not prevent bacterial STIs among cisgender women

Ketamine appears to hold promise in treating cocaine-use disorders

Spinal cord stimulation technology instantly improves arm and hand mobility in stroke patients

E-cigarettes as a first-line aid for smoking cessation in adults

COVID-19 vaccination associated with fewer heart attacks, strokes, and other cardiovascular issues

Activating or deactivating drugs with the help of light

Some parents may not be properly responding to elevated temperatures in children, poll suggests

Utilizing CRISPR to discover new therapy options for COPD

Genome editing prevents hypertrophic cardiomyopathy in mice

UTHSC researchers secure $308,000 grant from Department of Defense for dementia study

Toxic protein may be the cause of muscular dystrophy and arhinia

Proposal to scrap England’s long term plan for cancer could cost lives, experts warn

Everything there is to know about biosimilars eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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