Protein C News and Research

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Nanopores – the key to identifying amino acids in proteins

DNA and RNA sequencing has become the new watchword for the biological researchers, as this tells them exactly what is going on at cellular level in health and disease. However, it is a partial revelation unless we also know what is happening at the level of proteins as well.

19 Dec 2019

Caffeine may offset some negative health effects of obesogenic diet

A new study in rats suggests that caffeine may offset some of the negative effects of an obesogenic diet by reducing the storage of lipids in fat cells and limiting weight gain and the production of triglycerides.

19 Dec 2019

Study reveals new role for a triple-negative breast cancer target

Unlike almost every other organ, the mammary gland does not develop until after birth. And it's unusually dynamic, shape-shifting during menstrual cycles, puberty, pregnancy, and lactation.

19 Dec 2019

New mechanism that impairs Treg differentiation and stability in type 1 diabetes discovered

Regulatory T cells (Tregs) prevent excessive immune reactions in healthy people. In the development of autoimmune type 1 diabetes, this protection is not sufficiently effective.

19 Dec 2019

Researchers reveal the mystery in replication cycle of hepatitis D virus

A team led by Professor Patrick Labonté at the Institut National de la Recherche Scientifique in Montreal, Canada has identified the role of a key process in the replication cycle of the hepatitis D virus, an infection that is still very difficult to cure and affects 15 to 20 million people worldwide.

19 Dec 2019

FDA approves new drug to treat adults with advanced urothelial or bladder cancer

The U.S. Food & Drug Administration granted accelerated approval to the drug enfortumab vedotin (EV) to treat adult patients with advanced urothelial or bladder cancer.

19 Dec 2019

Artificial 'inclusion bodies' developed for sustained release of therapeutic proteins

Precision medicine is becoming increasingly important, achieving to create more efficient personalized therapies for each patient and innovative pharmacological developments.

19 Dec 2019

Scientists develop a drink based on whey, pectin from Zostera seagrass and fruit juice

Scientists of the Department of Food Science and Technology, School of Biomedicine, Far Eastern Federal University have developed a drink rich in vitamins and minerals that based on whey, pectin from seagrass Zostera, and fruit juice or nectar.

19 Dec 2019

First images of new gene editing complex which could upgrade CRISPR

Nobel Prize-winning technique used to capture images of a new gene-editing tool that could improve CRISPR-based tools.

19 Dec 2019

Suppressing MSUT2 gene may protect people from Alzheimer’s disease

In the wake of recent disappointments over clinical trials targeting amyloid plaque build-up in Alzheimer's disease, researchers are focusing more attention on misfolded tau protein, another culprit in brain diseases that cause dementia.

18 Dec 2019

Catastrophic macropinocytosis may aid in cancer treatment

In laboratory experiments, a metabolic inhibitor was able to kill a variety of human cancer cells of the skin, breast, lung, cervix and soft tissues through a non-apoptotic route -- catastrophic macropinocytosis.

18 Dec 2019

Traffic-related pollution increases a pregnant woman’s risk for hypertension

A new report published by the National Toxicology Program (NTP) indicates that air pollution derived from traffic could make a pregnant woman more likely to develop hypertension than otherwise. The study is based on an analysis of the association between traffic-related air pollution, or TRAP, with hypertensive disorders of pregnancy.

18 Dec 2019

Forgetful? Look at the time

An interesting new paper describes the discovery of a gene in mice that affects the degree of memory recall at various times of day. They found that this gene makes mice most forgetful at the time immediately before they wake.

18 Dec 2019

Heavy drinking damages the heart

Drinking too much destroys the liver, as is well known. A new study published in the Journal of the American Heart Association on December 18, 2019, shows that excessive alcohol consumption also damages the heart muscle. This is seen by a rise in the level of certain biological molecules in the blood.

18 Dec 2019

Scientists use supercomputers to shed light on skin cancer formation mechanism

Skin cancer, particularly melanoma, which is the deadliest and most serious type of human skin cancer, begins as a small lesion or blemish. Usually, these blemishes start off as harmless accumulation of melanocytes, which give the skin its color. As the disease progresses, it can spread throughout the body.

18 Dec 2019

Blue light may not be so bad for sleep

The sun provides warmth and a bright light with orange-yellow hues during the day. But at night, cold, dim, and white light from the Moon, which exposes people to light similar to blue wavelengths emitted by various types of artificial lighting. Previously, blue light has been dubbed as disruptive to a good night’s sleep.

18 Dec 2019

Study opens up new treatment possibilities for Wilms' tumor

As an embryo develops, its cells must learn what to do with the thousands of genes they've been equipped with. That's why each cell comes with a detailed gene-expression manual outlining exactly which genes should be switched on, to what extent, and when.

18 Dec 2019

Scientists explore role of IgG4 Abs in IgG4-related disease

Autoimmune diseases are a medical conundrum. In people with these conditions, the immune system of the body, the designated defense system, starts attacking the cells or organs of its own body, mistaking the self-cells for invading disease-causing cells. Often, the cause for this spontaneous dysfunction is not clear, and hence, treatment of these diseases presents a major and ongoing challenge.

18 Dec 2019

Different mutations in a single gene can have myriad effects on a person's health

Mount Sinai researchers have found that different mutations in a single gene can have myriad effects on a person's health, suggesting that gene therapies may need to do more than just replenish the missing or dysfunctional protein the gene is supposed to encode, according to a study published in Nature Genetics in November.

18 Dec 2019

Scientists develop computationally inspired method for preclinical study of anxiety

Nearly 40 million people in the U.S. have an anxiety disorder. While treatment options exist, treatment success varies, and many people do not respond to treatment until weeks or months after they begin anti-depressants

18 Dec 2019