Antigen News and Research

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Short-term immunity imparted by COVID-19 BNT162b2 vaccination in adolescents and children

Researchers demonstrated the short-term protection conferred by the SARS-CoV-2 BNT162b2 vaccination in adolescents and children.

27 May 2022

Combined treatment approach proves to be beneficial for prostate cancer patients

Practice-changing research from Cedars-Sinai Cancer shows that a combination of androgen deprivation therapy - a commonly used hormone injection - plus pelvic lymph node radiation, kept nearly 90% of clinical trial patients' prostate cancer at bay for five years.

26 May 2022

Study assesses the safety of breastfeeding during maternal SARS-CoV-2 infection

Researchers assessed the presence of anti-SARS-CoV-2 antibodies in human breast milk.

26 May 2022

Immunogenicity predictions reveal SARS-CoV-2 CD8+ T-cell epitopes

In a recent study posted to the bioRxiv* pre-print server, researchers identified several new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epitopes displayed on human leukocyte antigens class I (HLA-I) molecules.

26 May 2022

Model predicts scenarios that reveal the benefit of updating COVID vaccines

In a recent study posted to the bioRxiv* preprint server, scientists analyzed the necessity of revamping the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines to tackle the current dominant circulating viral variants.

26 May 2022

Mucosal COVID vaccine candidate powerfully protective in macaques

A recent research paper posted to the bioRxiv* preprint server illustrated the protective efficacy of the intranasal pediatric parainfluenza virus-vectored coronavirus disease 2019 (COVID-19) vaccine prospect, B/HPIV3/S-6P, in macaques.

26 May 2022

After SARS-CoV-2 infection, anti-chemokine antibodies correlate with better outcomes

A recent study posted to the bioRxiv* preprint server illustrated that specific chemokine antibodies aid in recognizing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) convalescent individuals with a desirable disease course.

26 May 2022

Researchers discover mechanisms underlying T-cell receptor's immunosuppressive function

Investigators have discovered the mechanisms underlying a T-cell receptor's immunosuppressive function, according to a study published Nature Immunology, findings that may provide insight into the development of novel precision therapeutics for chronic diseases, including cancer.

25 May 2022

Novel mechanism to turn on cancer-killing T cells identified

Over the past decade, researchers have made great strides in the development and administration of cancer immunotherapies, which use the body's own immune system to treat disease.

25 May 2022

Study measures viral antigen and inflammatory biomarkers in CSF of COVID-19 patients in relation to neurologic symptoms and disease severity

Researchers investigated the impact of coronavirus disease 2019 (COVID-19) on biomarkers in the cerebrospinal fluid (CSF).

25 May 2022

Review addresses the need for innovative adjuvant approaches and delivery strategies for the advancement of new mucosal vaccines

Researchers reviewed available mucosal vaccines discussing the current challenges and ways to advance the existing approaches.

25 May 2022

Researchers reveal novel tumor–macrophage interactions that promote peritoneal metastasis of ovarian cancer

A research team at the School of Biological Sciences, the University of Hong Kong, has revealed novel cellular and molecular interactions between cancer cells and tumor-associated macrophages that promote peritoneal metastasis of ovarian cancer.

25 May 2022

Computational modeling fine tunes RBD-1C aptamer against SARS-CoV-2 S protein

Researchers used the SARS-CoV-2 sequence against aptamers to perform the in silico selection of an aptamer against the SARS-CoV-2 S protein.

24 May 2022

The impact of SARS-CoV-2 nucleocapsid protein mutations on the performance of rapid antigen tests

The study findings showed that the rapid antigen tests with the DMS approach could accurately identify antibody escape mutations in the SARS-CoV-2 N protein.

24 May 2022

Hamster contact exposure challenge model assesses protection conferred by SARS-CoV-2 vaccination or prior infection against reinfection

Researchers assessed the neutralization efficacy of a saRNA vaccine targeting SARS-CoV-2 S protein against reinfection among hamsters with prior vaccination or infection.

24 May 2022

ATLAS assay reveals SARS-CoV-2 variant T-cell responses

Researchers utilize the ATLAS screening assay to reveal the antigen response profiles of T-cells to different SARS-CoV-2 variants.

23 May 2022

Health authorities must revolutionize testing to deal with future covid-19 prevalence

Dealing with lower covid-19 levels will require improved understanding of what diagnostic tests are best used for. It will also need more accurate tests, but as testing demand will fall, delivering that needs incentive-based support.

23 May 2022

Study suggests that recall of B cell memory may depend on relative locations of prime and boost immunization

A new study investigated whether a specific population of local Bmem cells in the proximal LNs produce secondary GC responses that are different from those at distal sites and if the location in humoral immunity is relevant only to nonlymphoid tissues.

23 May 2022

Study reports SARS-CoV-2 accessory proteins downregulate MHC-I expression using distinct mechanisms

Researchers observed SARS-CoV-2 downregulates the expression of MHC class I molecules.

23 May 2022

The design of immunogens for the SARS-CoV-2 spike protein using structure-guided epitope grafting and scaffolding methods

Researchers designed an efficient vaccine design against SARS-CoV-2 infections.

23 May 2022

Antigen News and Research

Short-term immunity imparted by COVID-19 BNT162b2 vaccination in adolescents and children

Combined treatment approach proves to be beneficial for prostate cancer patients

Study assesses the safety of breastfeeding during maternal SARS-CoV-2 infection

Immunogenicity predictions reveal SARS-CoV-2 CD8+ T-cell epitopes

Model predicts scenarios that reveal the benefit of updating COVID vaccines

Mucosal COVID vaccine candidate powerfully protective in macaques

After SARS-CoV-2 infection, anti-chemokine antibodies correlate with better outcomes

Researchers discover mechanisms underlying T-cell receptor's immunosuppressive function

Novel mechanism to turn on cancer-killing T cells identified

Study measures viral antigen and inflammatory biomarkers in CSF of COVID-19 patients in relation to neurologic symptoms and disease severity

Review addresses the need for innovative adjuvant approaches and delivery strategies for the advancement of new mucosal vaccines

Researchers reveal novel tumor–macrophage interactions that promote peritoneal metastasis of ovarian cancer

Computational modeling fine tunes RBD-1C aptamer against SARS-CoV-2 S protein

The impact of SARS-CoV-2 nucleocapsid protein mutations on the performance of rapid antigen tests

Hamster contact exposure challenge model assesses protection conferred by SARS-CoV-2 vaccination or prior infection against reinfection

ATLAS assay reveals SARS-CoV-2 variant T-cell responses

Health authorities must revolutionize testing to deal with future covid-19 prevalence

Study suggests that recall of B cell memory may depend on relative locations of prime and boost immunization

Study reports SARS-CoV-2 accessory proteins downregulate MHC-I expression using distinct mechanisms

The design of immunogens for the SARS-CoV-2 spike protein using structure-guided epitope grafting and scaffolding methods

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