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Research uncovers mechanism implicated in defective function of tumor-associated dendritic cells

A new study from The Wistar Institute revealed the mechanism implicated in the defective function of tumor-associated dendritic cells (DCs), a specialized type of immune cells that expose the antigens on their surface to activate the T cells.

15 Dec 2017

Study provides insights into molecular mechanisms regulating cellular fate of SCCs

Researchers at Kanazawa University report in EMBO Reports, 7 December 2017, new molecular mechanisms regulating cellular fate of squamous cell carcinomas.

15 Dec 2017

Belgian researchers create transplantable artificial ovary prototype

Belgian researchers have taken important steps towards creating transplantable artificial ovaries. Once successful, these could be of value to women struggling with infertility or cancer patients who cannot conceive after undergoing radiation or chemotherapy.

13 Dec 2017

Study provides new insights into mechanism of tumor survival in glioblastoma

A Northwestern Medicine study, published in the journal Cancer Cell, has provided new insights into a mechanism of tumor survival in glioblastoma and demonstrated that inhibiting the process could enhance the effects of radiation therapy.

11 Dec 2017

Two immunotherapy approaches for multiple myeloma show hope

Researchers from the University of Pennsylvania's Abramson Cancer Center have developed two experimental immunotherapy methods that include one chimeric antigen receptor (CAR) T cell therapy for the treatment of multiple myeloma patients who were not responding to other treatments.

11 Dec 2017

Family members who do not carry inherited mutation have higher risk of melanoma

In families who carry certain inherited mutations that increase the risk for melanoma, members who do not carry the mutation also have an increased risk of melanoma, a study from Karolinska Institutet published in Genetics in Medicine reports.

8 Dec 2017

Bacteria may be involved in progression of cancers in the mouth, study suggests

Scientists at the School of Dental Science in Trinity have made an important discovery involving bacteria and a pre-cancerous growth called oral leukoplakia which can precede oral cancer.

7 Dec 2017

Fusobacterium may play role in colon cancer growth, study finds

Like nomads who carry tokens of home on their travels, colorectal cancer cells that spread to other parts of the body appear to bring several of the species of bacteria that were their companions in the colon, Dana-Farber Cancer Institute scientists report in a new study in the journal Science.

7 Dec 2017

Brazilian researchers identify genes linked to melanoma progression

When researchers at the University of São Paulo in Brazil treated human melanoma cell lines with a synthetic compound similar to curcumin, one of the pigments that give turmeric its orange color, they identified genes with altered expression in potentially invasive tumors and malignant cells resistant to chemotherapy.

6 Dec 2017

Mount Sinai surgeons use BABA technique to remove metastatic cancer in the lateral neck

A team of surgeons at Mount Sinai Beth Israel, led by Hyunsuk Suh, MD, Assistant Professor in the Department of Surgery at the Icahn School of Medicine at Mount Sinai, have performed the first robot-assisted radical neck dissection in the United States using the bilateral axillo-breast approach (BABA), a surgery that involves removing all of the lymph nodes on one side of the neck.

6 Dec 2017

Specific protein negatively affects pancreatic cells and leads to cancer growth

Pancreatic cancer is one of the most aggressive forms of cancer and is currently very difficult to treat. However, the last few years have seen advances in the scientific understanding of how this cancer develops at a molecular level.

6 Dec 2017

Researchers identify vulnerability for glioblastoma subtypes

Glioblastoma, the most common and aggressive form of brain cancer, typically fails to respond to treatment or rapidly becomes drug resistant.

1 Dec 2017

Understanding molecular mechanisms of signaling pathways to inhibit cancer invasion

The German Research Foundation has approved the renewal application for the Collaborative Research Center 850 "Control of Cell Motility in Morphogenesis, Cancer Invasion, and Metastasis".

30 Nov 2017

Researchers determine 'sweet spot' could enhance diagnosis of melanoma skin lesions

Too much, too little, just right. It might seem like a line from "Goldilocks and the Three Bears," but actually describes an important finding from researchers in Florida Atlantic University's College of Engineering and Computer Science.

28 Nov 2017

New findings offer hope for children with aggressive brain tumors

Findings published in Oncotarget offer new hope for children with highly aggressive brain tumors like atypical teratoid/rhabdoid tumor (AT/RT) and medulloblastoma.

28 Nov 2017

New cancer drug begins clinical trial in human patients with rare brain tumor

A drug that spurs cancer cells to self-destruct has been cleared for use in a clinical trial of patients with anaplastic astrocytoma, a rare malignant brain tumor, and glioblastoma multiforme, an aggressive late-stage cancer of the brain.

28 Nov 2017

Study finds specific tumor environment that stimulates cancer cells to metastasize

A new study, conducted by a team of researchers from the University of California, San Diego, has identified how the environment surrounding a tumor can stimulate metastatic behavior in the individual cancer cells. Researchers found that the tumor cells activate a particular set of genes and begin to form blood vessel-like structures when they are confined in a densely packed environment.

22 Nov 2017

Oncologists find new biomarker for breast cancer having poor prognosis

With the support of the FWF, an oncologist found a biomarker for breast cancer having a poor prognosis and developed two viable methods to detect it in tissue samples.

22 Nov 2017

Scientists discover how tumor environment can trigger metastatic behavior in cancer cells

A team of bioengineers and bioinformaticians at the University of California San Diego have discovered how the environment surrounding a tumor can trigger metastatic behavior in cancer cells.

22 Nov 2017

Research findings offer prime drug targets to treat rare liver cancer that strikes young people

After years of rigorous research, a team of scientists has identified the genetic engine that drives a rare form of liver cancer. The findings offer prime targets for drugs to treat the usually lethal disease, fibrolamellar hepatocellular carcinoma (FL-HCC), which mainly strikes adolescents and young adults.

22 Nov 2017

Malignant News and Research

Research uncovers mechanism implicated in defective function of tumor-associated dendritic cells

Study provides insights into molecular mechanisms regulating cellular fate of SCCs

Belgian researchers create transplantable artificial ovary prototype

Study provides new insights into mechanism of tumor survival in glioblastoma

Two immunotherapy approaches for multiple myeloma show hope

Family members who do not carry inherited mutation have higher risk of melanoma

Bacteria may be involved in progression of cancers in the mouth, study suggests

Fusobacterium may play role in colon cancer growth, study finds

Brazilian researchers identify genes linked to melanoma progression

Mount Sinai surgeons use BABA technique to remove metastatic cancer in the lateral neck

Specific protein negatively affects pancreatic cells and leads to cancer growth

Researchers identify vulnerability for glioblastoma subtypes

Understanding molecular mechanisms of signaling pathways to inhibit cancer invasion

Researchers determine 'sweet spot' could enhance diagnosis of melanoma skin lesions

New findings offer hope for children with aggressive brain tumors

New cancer drug begins clinical trial in human patients with rare brain tumor

Study finds specific tumor environment that stimulates cancer cells to metastasize

Oncologists find new biomarker for breast cancer having poor prognosis

Scientists discover how tumor environment can trigger metastatic behavior in cancer cells

Research findings offer prime drug targets to treat rare liver cancer that strikes young people

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