Neurodegenerative Diseases News and Research

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Rapamycin prevents age-related brain vascular deterioration, study shows

A just-released study by UT Health San Antonio and collaborating institutions shows age-related decreases in blood flow to the brain and memory loss can be modified with the drug rapamycin.

6 Nov 2019

Researchers find genes from 'fossil' virus in human DNA to be active

Genes from a virus that was stitched into the human genome thousands of years ago are active, producing proteins in the human brain and other tissues, according to researchers at the University of Washington School of Medicine and the Laval University School of Medicine in Quebec, Canada.

5 Nov 2019

Newly identified gene variant may offer potential treatment for Alzheimer's disease

Defying the odds, an individual at high risk for early-onset Alzheimer's disease remained dementia-free for many years beyond what was anticipated.

4 Nov 2019

Genetic mutation of APOE gene may provide protection against Alzheimer's disease

A team of researchers has identified that a genetic mutation of the APOE gene, the major susceptibility gene for late-onset Alzheimer's disease, may provide protection against the devastating neurological illness.

4 Nov 2019

Scientists identify protein that pulls the brake on nerve growth

During embryonic development, nerve cells form thin, long extensions, which they use to wire up a complex network, the brain. Scientists from the German Center for Neurodegenerative Diseases in Bonn have now identified a protein that regulates the growth of these extensions by pulling a brake.

31 Oct 2019

Discovery has potential to put the brakes on Parkinson's 'runaway train'

Researchers at the University of Dundee have made a discovery they believe has the potential to put the brakes on the 'runaway train' that is Parkinson's disease.

31 Oct 2019

Key gene mutated in familial Alzheimer's regulates differentiation of neurons

An international team of researchers led by the Institute of Neuroscience at the Universitat Autònoma de Barcelona describes a new route that promotes differentiation of neurons.

30 Oct 2019

Researchers make progress toward gene-based strategies to treat inherited neurometabolic diseases

Researchers are making great strides toward developing gene-based strategies to treat a variety of inherited neurometabolic diseases characterized by severe neurological involvement.

29 Oct 2019

Nerve cell protection without side effects on erythropoiesis

The hormone erythropoietin (Epo) is a well-known doping substance that has a long history of abuse in endurance sports, such as cycling. In addition to promoting red blood cell production (erythropoiesis), which improves the oxygen supply in the organism, Epo also protects nerve cells from cell death.

25 Oct 2019

Researchers receive $9.7 million NIH grant to study TBI and neurodegenerative diseases

An international team of experts led by researchers in the Perelman School of Medicine at the University of Pennsylvania and University of Glasgow has been awarded a $9.7 million, five-year grant from the National Institute of Neurological Disorders and Stroke and National Institute for Aging to establish CONNECT-TBI--a program spanning 12 institutions which will study traumatic brain injury and related neurodegenerative diseases.

24 Oct 2019

Novel agent reduces buildup of toxic proteins in Parkinson's and Alzheimer's animal models

Neuroscientists at Georgetown University Medical Center say they have developed and tested an agent that reduces the buildup of toxic proteins in animal models of both Parkinson's and Alzheimer's diseases, and improves cognitive and motor behavior.

23 Oct 2019

NIA-funded study to examine overall benefits and risks of statins in older adults

The National Institute on Aging has funded a major study to examine the overall benefits and risks of cholesterol-lowering drugs known as statins in adults age 75 or older without cardiovascular disease.

23 Oct 2019

Research suggests greater complexity in cellular protein movement

A new imaging technique that makes it possible to match motor proteins with the cargo they carry within a cell is upending a standard view of how cellular traffic reaches the correct destination.

23 Oct 2019

Researchers elucidate properties of blood factor involved in weight loss and aging

Aging is a process that affects all functions of the human body, particularly brain function. However, aging can be delayed through lifestyle changes (physical exercise, restricting calorie intake, etc.).

22 Oct 2019

Link found between genetic variations and size of the brainstem, other subcortical structures

Researchers have found a link between 48 common genetic variations and the size of the brainstem and other subcortical structures deep within the brain.

21 Oct 2019

SciLifeLab and AstraZeneca establish cryo-EM collaboration to advance biomedicine

The study published in Science Advances reveals the mechanism by which the receptor tyrosine kinase RET can increase neuronal survival in degenerative diseases. To understand the mechanism of this signaling complex, the researchers solved the cryo-EM structure of its extracellular region, employing a new approach for data collection.

21 Oct 2019

Semantic memory deficits linked to eating disorders in patients with dementia

For the first time, it has been shown that deficits of semantic memory, an ability we use to recognize objects and use them correctly, are involved in specific eating disorders shared by patients suffering from dementia.

17 Oct 2019

UCLA research identifies potential strategy that may halt Huntington's disease

A new study examining the role that star-shaped brain cells called astrocytes play in Huntington's disease has identified a potential strategy that may halt the disease and repair some of the damage it causes.

16 Oct 2019

Stony Brook-led study reveals how proteome collapse process drives cell death and aging

Cells undergo natural aging and death, processes that impact a multitude of cellular factors. A new Stony Brook University-led study, to be published in PNAS, provides a biophysical model that reveals how damage accumulates in the shapes of cellular proteins with age and is a trigger to death.

16 Oct 2019

New test could detect abnormal forms of protein associated with tauopathies

National Institutes of Health scientists have developed an ultrasensitive new test to detect abnormal forms of the protein tau associated with uncommon types of neurodegenerative diseases called tauopathies.

16 Oct 2019

Neurodegenerative Diseases News and Research

Rapamycin prevents age-related brain vascular deterioration, study shows

Researchers find genes from 'fossil' virus in human DNA to be active

Newly identified gene variant may offer potential treatment for Alzheimer's disease

Genetic mutation of APOE gene may provide protection against Alzheimer's disease

Scientists identify protein that pulls the brake on nerve growth

Discovery has potential to put the brakes on Parkinson's 'runaway train'

Key gene mutated in familial Alzheimer's regulates differentiation of neurons

Researchers make progress toward gene-based strategies to treat inherited neurometabolic diseases

Nerve cell protection without side effects on erythropoiesis

Researchers receive $9.7 million NIH grant to study TBI and neurodegenerative diseases

Novel agent reduces buildup of toxic proteins in Parkinson's and Alzheimer's animal models

NIA-funded study to examine overall benefits and risks of statins in older adults

Research suggests greater complexity in cellular protein movement

Researchers elucidate properties of blood factor involved in weight loss and aging

Link found between genetic variations and size of the brainstem, other subcortical structures

SciLifeLab and AstraZeneca establish cryo-EM collaboration to advance biomedicine

Semantic memory deficits linked to eating disorders in patients with dementia

UCLA research identifies potential strategy that may halt Huntington's disease

Stony Brook-led study reveals how proteome collapse process drives cell death and aging

New test could detect abnormal forms of protein associated with tauopathies

eBook: Using iPSCs models for human disease research and drug discovery eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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