Omicron News and Research

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Antigenic differences between Omicron BA.1 and BA.2 SARS-CoV-2 variants

A new study identifies the antigenic differences that exist between the Omicron BA.2 and BA.1 variants.

2 Mar 2022

Serological test to assess presence of immunoglobulin isotypes targeted against antigens routinely used in COVID-19 diagnosis

The current study discusses a reliable ELISA that can detect three isotypes of antibody against three SARS-CoV-2 antigens.

2 Mar 2022

Study reports substantial loss of protection one month after complete SARS-CoV-2 BNT162b2 immunization in children

A new study evaluated the efficacy of Pfizer’s BNT162b2 vaccine in children aged 17 years or younger after the emergence of the SARS-CoV-2 Omicron variant.

2 Mar 2022

Population-level health and economic impact of the Pfizer-BioNTech COVID-19 vaccine in first year of rollout in the US

A new study shows the impact of the vaccine program on the state of public health in the USA.

2 Mar 2022

Study finds booster shot did produce effective levels of neutralizing antibodies against omicron

A new study using serum from human blood samples suggests neutralizing antibody levels produced by two-dose mRNA vaccines against the original and early variants of the SARS-CoV-2 virus wane substantially over time, and offer essentially no protection against the omicron variant.

2 Mar 2022

Masks made of woven fabrics are lousy air filters

Like many other viruses, COVID-19 is transmitted primarily via particles carried in the air. An infected person breathes out particles containing the virus into the air, which can then be inhaled by another person, who then becomes infected.

1 Mar 2022

Government to revoke regulations making COVID-19 vaccination as a condition of deployment

Regulations making COVID-19 vaccination a condition of deployment in health and social care will be revoked on Tuesday 15 March, the Health and Social Care Secretary has confirmed today (Tuesday 1 March).

1 Mar 2022

mRNA vaccines found to generate neutralizing antibodies against SARS-CoV-2 Omicron variant

A new study assessed the immunogenicity of messenger-ribonucleic acid vaccines to generate cross-reactive neutralizing antibodies against the SARS-CoV-2 Omicron variant in convalescent COVID-19 patients.

1 Mar 2022

Risk of death involving COVID-19 following infection from Omicron relative to Delta

Researchers conducted a retrospective study on a cohort of patients in England with SARS-CoV-2 positive test results.

1 Mar 2022

Impact of COVID-19 boosters on protection against SARS-CoV-2 infection in a highly vaccinated population

A recent study analyzed the impact of COVID-19 booster vaccines against the SARS-CoV-2 Omicron VOC in a vaccinated population.

1 Mar 2022

Association between booster breakthrough infections with the SARS-CoV-2 Omicron variant and time-since-vaccination

A recent study assessed the waning efficacy of the BioNTech/Pfizer BNT162b2 mRNA vaccine against the SARS-CoV-2 Omicron VOC.

1 Mar 2022

Epistatic shifts rationalize mutational constraints of SARS-CoV-2 receptor-binding domain

Researchers used deep mutational scans to measure the effect of each amino-acid mutation in the receptor-binding domain of SARS-CoV-2 Wuhan-Hu-1, Alpha, Beta, Delta, and Eta variants.

1 Mar 2022

Effect of mRNA-based COVID-19 vaccination in multiple myeloma patients

In a new study, researchers evaluated the immune responses induced by the mRNA-based SARS-CoV-2 vaccination against SARS-CoV-2 variants in multiple myeloma patients.

1 Mar 2022

J&J-vaxxed, mRNA-boosted, and pondering a third shot

Yes, we are all exhausted by the covid pandemic. Flummoxed by the constantly shifting science and guidelines. Worried about a succession of scary new variants, each with its own name, like hurricanes.

1 Mar 2022

Study identifies olfactory dysfunction as an early symptom of COVID-19

In a new study, scientists researched olfactory loss and dysfunction among COVID-19 patients to objectively characterize it as a symptom of COVID-19.

1 Mar 2022

Study finds MK-4482 inhibits replication of multiple SARS-CoV-2 variants of concern in Syrian hamster COVID-19 model

Researchers found that an antiviral drug, was effective against SARS-CoV-2 variants, including the recently emerged Omicron variant, in Syrian hamsters.

1 Mar 2022

Study proposes structural explanation for immune evasion effect of SARS-CoV-2 BA.2 variant mutations S371L/F

Researchers proposed a structural mechanism to explain immune evasion effects of the two-point mutations, S371L and S371F, in the receptor-binding domain of the SARS-CoV-2 Omicron variant.

1 Mar 2022

Biophysical fitness profile of SARS-CoV-2 Delta variant

In a recent study posted to the bioRxiv* preprint server, researchers investigated the biophysical fitness landscape of the receptor-binding domain (RBD) of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta variant.

1 Mar 2022

Encouraging in vitro results with SARS-CoV-2-spike-specific polyclonal antibody fragments

In a recent study posted to the bioRxiv* preprint server, researchers demonstrated the potent neutralizing ability of a polyclonal equine antibody (Ab), FBR-002, against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs), including Omicron.

28 Feb 2022

Novel respiratory model predicts mechanisms altered by SARS-CoV-2 variants

Researchers study cell infection and viral replication methods affected by SARS-CoV-2 mutations through a novel respiratory model.

28 Feb 2022

Omicron News and Research

Antigenic differences between Omicron BA.1 and BA.2 SARS-CoV-2 variants

Serological test to assess presence of immunoglobulin isotypes targeted against antigens routinely used in COVID-19 diagnosis

Study reports substantial loss of protection one month after complete SARS-CoV-2 BNT162b2 immunization in children

Population-level health and economic impact of the Pfizer-BioNTech COVID-19 vaccine in first year of rollout in the US

Study finds booster shot did produce effective levels of neutralizing antibodies against omicron

Masks made of woven fabrics are lousy air filters

Government to revoke regulations making COVID-19 vaccination as a condition of deployment

mRNA vaccines found to generate neutralizing antibodies against SARS-CoV-2 Omicron variant

Risk of death involving COVID-19 following infection from Omicron relative to Delta

Impact of COVID-19 boosters on protection against SARS-CoV-2 infection in a highly vaccinated population

Association between booster breakthrough infections with the SARS-CoV-2 Omicron variant and time-since-vaccination

Epistatic shifts rationalize mutational constraints of SARS-CoV-2 receptor-binding domain

Effect of mRNA-based COVID-19 vaccination in multiple myeloma patients

J&J-vaxxed, mRNA-boosted, and pondering a third shot

Study identifies olfactory dysfunction as an early symptom of COVID-19

Study finds MK-4482 inhibits replication of multiple SARS-CoV-2 variants of concern in Syrian hamster COVID-19 model

Study proposes structural explanation for immune evasion effect of SARS-CoV-2 BA.2 variant mutations S371L/F

Biophysical fitness profile of SARS-CoV-2 Delta variant

Encouraging in vitro results with SARS-CoV-2-spike-specific polyclonal antibody fragments

Novel respiratory model predicts mechanisms altered by SARS-CoV-2 variants

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