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Drug company pipelines are filling up with new molecules to help people lose weight

Drugs that promise to help people lose weight have had a checkered past, such as the infamous fen-phen that was pulled from the market in 1997 after reports of heart valve damage. But now, drug company pipelines are filling up with new molecules that aim to help people safely shed extra pounds, according to a cover story in Chemical & Engineering News, an independent news outlet of the American Chemical Society.

21 Oct 2021

Infrared light therapy may potentially benefit people with dementia

Infrared light therapy might have the potential to help people living with dementia, according to researchers.

19 Oct 2021

Phase 2 trial shows COVID-19 recombinant protein vaccine elicits promising immunogenicity responses

Researchers performed a large-scale, double-blind, placebo-controlled phase two trial to assess the efficacy, safety, and immune response elicited from vaccination with MVC-COV1901.

19 Oct 2021

Researchers illustrate the importance and value of sharing negative research results

In the era of "publish or perish," research results that disprove the hypothesis tested often go unpublished. In addition, many researchers who have been unable to reproduce results from other laboratories have found it difficult to publish their findings.

18 Oct 2021

FDA-approved drug encourages sensory neurons to regrow after injury

A spinal cord injury damages the lines of communication between the body and brain, impeding the signals that drive movement and sensation.

18 Oct 2021

Interferon beta-1a plus remdesivir not superior to remdesivir alone in hospitalized COVID-19 patients

A clinical trial has found that treatment with the immunomodulator interferon beta-1a plus the antiviral remdesivir was not superior to treatment with remdesivir alone in hospitalized adults with COVID-19 pneumonia.

18 Oct 2021

New trial shows vaginal laser therapy treatments may not work at all

This laser is supposed to rejuvenate vaginal tissue. But scientists say it’s no better than a placebo.

15 Oct 2021

Severe COVID-19 pneumonia patients with high ferritin show better outcomes after steroid treatment

During the entire pandemic, physicians treating patients with severe Covid-19 pneumonia continuously looked for hints and signs on what may enable patients to have better outcomes.

15 Oct 2021

Aspirin use daily by healthy adults could be harmful

Scientists determine if the daily use of aspirin prolongs a healthy life span that is defined as being free from dementia and physical disability.

14 Oct 2021

Oxytocin does not appear to overcome social deficits in children with ASD, study suggests

Regular doses of the hormone oxytocin do not appear to overcome deficits in social functioning among children with autism spectrum disorder (ASD), suggests a study funded by the National Institutes of Health.

13 Oct 2021

Novel vaccine demonstrates high efficacy for prevention of COVID-19

The clinical trial studied the efficacy of Novavax’s COVID-19 vaccine, NVX-CoV2373, and found it highly effective in preventing mild, moderate, and severe COVID-19 after full vaccination.

12 Oct 2021

Combination therapies are the most effective smoking cessation medicines, review finds

Combination therapies, particularly varenicline and nicotine replacement therapy (NRT) combined, are the most effective tobacco cessation pharmacotherapies, the largest review to examine the effectiveness and safety of electronic cigarettes (e-cigarettes) and medicines that people use to quit tobacco has found.

11 Oct 2021

Inactivated polio vaccine induces antibodies that block SARS-CoV-2 RNA synthesis

A new study introduces the possibility that the inactivated polio vaccine can elicit antibodies that inhibit SARS-CoV-2 nucleic acid synthesis.

10 Oct 2021

Oral and intranasal COVID-19 vaccines show promising results in hamster model

A new preprint discusses the protective effect of an oral adenovirus-vectored vaccine based on the SARS-CoV-2 spike against viral transmission and disease in hamsters.

8 Oct 2021

Existing drug reduces obesity and fatty liver in mice without changes in food intake or daily activity

Researchers at Johns Hopkins Medicine have found that a drug first developed to treat Alzheimer's disease, schizophrenia and sickle cell disease reduces obesity and fatty liver in mice and improves their heart function — without changes in food intake or daily activity.

7 Oct 2021

Study sheds light on the beneficial effects of peanut consumption in young and healthy people

A study published in the journal Clinical Nutrition provides new knowledge on the health effects of a diet rich in nuts.

7 Oct 2021

COVID-19 vaccine clinical trial for children is underway in St. Louis

A pediatric COVID-19 vaccine clinical trial is underway in St. Louis. Led by Washington University School of Medicine, about 140 area children will receive the two-shot Moderna vaccine or placebo at St. Louis Children's Hospital as part of a clinical trial involving about 100 medical institutions in the U.S. and Canada.

6 Oct 2021

Elevated allostatic load may impact treatment completion and breast cancer survival outcomes

Elevated allostatic load was associated with a lower likelihood of completing chemotherapy and a lower overall survival rate in patients with lymph node-positive or high-risk lymph node-negative HER2-negative breast cancer, according to results presented at the 14th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, held online October 6-8, 2021.

6 Oct 2021

Moderna COVID vaccine booster dose results in immune memory

A recent study presents evidence that a booster dose of the Moderna vaccine can induce a robust memory immune response against COVID-19.

6 Oct 2021

AstraZeneca COVID-19 vaccine safe and effective in phase 3 U.S., Chile, and Peru trial

A new study reports on the results of phase III clinical trial on the safety and efficacy of the AstraZeneca-Oxford COVID-19 vaccine.

5 Oct 2021

Placebo News and Research

Drug company pipelines are filling up with new molecules to help people lose weight

Infrared light therapy may potentially benefit people with dementia

Phase 2 trial shows COVID-19 recombinant protein vaccine elicits promising immunogenicity responses

Researchers illustrate the importance and value of sharing negative research results

FDA-approved drug encourages sensory neurons to regrow after injury

Interferon beta-1a plus remdesivir not superior to remdesivir alone in hospitalized COVID-19 patients

New trial shows vaginal laser therapy treatments may not work at all

Severe COVID-19 pneumonia patients with high ferritin show better outcomes after steroid treatment

Aspirin use daily by healthy adults could be harmful

Oxytocin does not appear to overcome social deficits in children with ASD, study suggests

Novel vaccine demonstrates high efficacy for prevention of COVID-19

Combination therapies are the most effective smoking cessation medicines, review finds

Inactivated polio vaccine induces antibodies that block SARS-CoV-2 RNA synthesis

Oral and intranasal COVID-19 vaccines show promising results in hamster model

Existing drug reduces obesity and fatty liver in mice without changes in food intake or daily activity

Study sheds light on the beneficial effects of peanut consumption in young and healthy people

COVID-19 vaccine clinical trial for children is underway in St. Louis

Elevated allostatic load may impact treatment completion and breast cancer survival outcomes

Moderna COVID vaccine booster dose results in immune memory

AstraZeneca COVID-19 vaccine safe and effective in phase 3 U.S., Chile, and Peru trial

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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