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Researchers develop promising new breast cancer diagnostic marker

Indiana University School of Medicine researchers have developed a new breast cancer diagnostic marker that could enable physicians to more easily determine which patients have a less aggressive form of the disease that may not require chemotherapy treatment.

21 Jun 2009

Some parents misdiagnosing milk formula intolerance

Some parents may be unnecessarily switching infant milk formulas for their healthy infants. A study published in BioMed Central's open access Nutrition Journal, found that many parents misinterpret common baby behaviors as milk intolerance and needlessly switch formulas without consulting a health professional.

18 Jun 2009

Gout gene discovered

Having partnered last year with an international team that surveyed the genomes of 12,000 individuals to find a genetic cause for gout, Johns Hopkins scientists now have shown that the malfunctioning gene they helped uncover can lead to high concentrations of blood urate that forms crystals in joint tissue, causing inflammation and pain - the hallmark of this disease.

18 Jun 2009

Discovery of candidate tumor suppressor gene and potential biomarker for colorectal cancer

Researchers have identified a new candidate tumor suppressor gene in colorectal cancer and examined its use as a potential biomarker in stool samples, according to a new study published online June 17 in the Journal of the National Cancer Institute.

17 Jun 2009

Circadian Technologies granted significant European patent

Circadian Technologies Limited (ASX:CIR) announced today that its subsidiary company, Vegenics Limited, has been granted European Patent 1749836 covering the use of VEGF-D protein and antibodies to VEGF-D in a broad spectrum of therapeutic indications, including the treatment of cancer.

17 Jun 2009

Genome-wide map shows precisely where microRNAs do their work

MicroRNAs are the newest kid on the genetic block. By regulating the unzipping of genetic information, these tiny molecules have set the scientific world alight with such wide-ranging applications as onions that can't make you cry and therapeutic potential for new treatments for viral infections, cancer and degenerative diseases. But the question remains: How do they work?

17 Jun 2009

Discovery of the cell's water gate may lead to new cancer drugs

The flow of water into and out from the cell may play a crucial role in several types of cancer. Scientists at the University of Gothenburg have now found the gate that regulates the flow of water into yeast cells.

17 Jun 2009

Chitosan and polyester ‘combo’ creates mixed-fiber material for nerve repair

In the clothing industry it's common to mix natural and synthetic fibers. Take cotton and add polyester to make clothing that's soft, breathable and wrinkle free.

17 Jun 2009

Enzyme TFIIH kinase found to be involved in epigenetic regulation

For many years scientists have known that the numerous biological functions of an organism are not regulated solely by the DNA sequence of its genes: Superordinate regulatory mechanisms exist that contribute to determining the fate of genes. Although they are not anchored in the DNA, they can even be passed on to subsequent generations to a certain extent. Intensive research in recent years has shown that these mechanisms - bundled under the term epigenetics, are very multifaceted and complex.

17 Jun 2009

Discovery of genetic markers to help fight diabetes

Translational Genomics Research Institute (TGen) scientists have identified five genetic biomarkers that could help lead to improved treatments, with fewer side-effects, for patients with diabetes.

17 Jun 2009

Simple blood test detects molecular marker of aging in humans

In 2004, researchers at the University of North Carolina at Chapel Hill Lineberger Comprehensive Cancer Center announced a crucial discovery in the understanding of cellular aging. They found that as cells and tissues age, the expression of a key protein, called p16INK4a, dramatically increases in most mammalian organs. Because p16INK4a is a tumor suppressor protein, cancer researchers are interested in its role in cellular aging and cancer prevention.

17 Jun 2009

Discovery of gene vital to early embryonic cells forming a normal heart and skull

New research from Cincinnati Children's Hospital Medical Center highlights the critical role a certain gene and its protein play during early embryonic development on formation of a normal heart and skull.

16 Jun 2009

Genomic discovery: Protecting kidney function during heart failure

Mayo Clinic cardiology researchers have found a peptide that helps preserve and improve kidney function during heart failure, without affecting blood pressure. Earlier variations of this peptide caused blood pressure to drop limiting the potential benefits to the kidneys. The findings appear in the current Proceedings of the National Academy of Sciences.

16 Jun 2009

New findings on how stress causes sexual dysfunction and infertility

University of California, Berkeley, researchers have found what they think is a critical and, until now, missing piece of the puzzle about how stress causes sexual dysfunction and infertility.

16 Jun 2009

Could hormones explain gender differences in neurological disease?

Neurological diseases including Parkinson's, Tourette's, attention deficit hyperactivity disorder (ADHD), Alzheimer's, and schizophrenia are all associated with alterations in dopamine-driven function involving the dopamine transporter (DAT).

16 Jun 2009

New form of radiotherapy could revolutionize treatment for recurrent prostate cancer

A new study shows that an alpha-particle emitting radiopeptide - radioactive material bound to a synthetic peptide, a component of protein - is effective for treating prostate cancer in mice, according to researchers at SNM's 56th Annual Meeting in Toronto.

15 Jun 2009

Inflammation of microglia may not be associated with dementia in Alzheimer's disease

The idea that anti-inflammatory drugs might protect people struggling with dementia from Alzheimer's disease has received a blow with the online release of a study of human brain tissue in Acta Neuropathologica.

15 Jun 2009

Discovery in dendritic cell signalling pathways pave way for new therapeutic targets

Scientists from A*STAR's Singapore Immunology Network (SIgN) and the University of Milano-Bicocca, Italy, have discovered another signaling pathway for the activation and apoptosis, or programmed cell death, of dendritic cells. This discovery was published in the advanced online publication of Nature on 15 Jun 2009.

15 Jun 2009

Experimental imaging technique reveals ‘tell tale’ brain plaques in Alzheimer's

Researchers at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory have demonstrated a new, highly detailed x-ray imaging technique that could be developed into a method for early diagnosis of Alzheimer's disease.

15 Jun 2009

Protein regulates movement of mitochondria in brain cells

Scientists have identified a protein in the brain that plays a key role in the function of mitochondria - the part of the cell that supplies energy, supports cellular activity, and potentially wards off threats from disease.The discovery, which was reported today in the Journal of Cell Biology, may shed new light on how the brain recovers from stroke.

15 Jun 2009