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Leukemia drug increases brain dopamine, lowers toxic proteins linked to Parkinson's or dementia

A small phase I study provides molecular evidence that an FDA-approved drug for leukemia significantly increased brain dopamine and reduced toxic proteins linked to disease progression in patients with Parkinson's disease or dementia with Lewy bodies.

12 Jul 2016

Prevalence of global diabetes has been vastly underestimated, say Monash researchers

A landmark paper led by Monash University with partners in the UK and US suggests there may be more than 100 million people with diabetes globally than previously thought.

11 Jul 2016

Innovative organ donation program allows living donors to donate kidney in advance

Gift certificate, layaway plan or voucher. Call it what you want, but an innovative organ donation program initiated at UCLA has started to spread to other transplant programs across the United States.

11 Jul 2016

Scientists discover new mechanism by which TNF protects against intracellular pathogens

Tumour necrosis factor (TNF), a messenger substance in the immune system, plays an important role in triggering chronic inflammatory diseases. For this reason, TNF inhibitors are a standard form of treatment for patients with rheumatoid arthritis and certain inflammatory bowel diseases.

11 Jul 2016

Women who undergo axillary node surgery for breast cancer more likely to develop chronic pain

An analysis led by McMaster University researchers has found that women who undergo armpit lymph node surgery for breast cancer are much more likely to develop chronic pain.

11 Jul 2016

Study identifies new blood markers to accurately diagnose Gulf War Illness

Based on a study of 85 Gulf War veterans, Veterans Affairs researchers in Minneapolis have developed a tentative panel of blood markers they say can verify a diagnosis of Gulf War Illness with 90 percent accuracy.

11 Jul 2016

Non-drug solutions for postpartum depression: an interview with Dr David Brock & Christopher Thatcher

Postpartum depression (PPD) is reported to occur in 10-15% of delivering women with an estimated 400,000 women affected annually in the US. It is the most common complication of childbirth and is a significant public health concern.

11 Jul 2016

Single dose of new molecule could protect the brain from cognitive impairments after mTBI

A new molecule could protect the brain from cognitive impairments after a mild traumatic brain injury, according to Hebrew University of Jerusalem scientists.

11 Jul 2016

Thousands of volunteers join clinical trial to help transform early detection of diabetic eye disease

More than 4,500 people from Liverpool with diabetes have volunteered to join a clinical trial funded by the National Institute for Health Research to help transform early detection of diabetic eye disease.

11 Jul 2016

UChicago to help enroll 150,000 participants in President’s PMI Cohort Program

The University of Chicago is one of three Illinois academic institutions that will work together to help launch President Obama's Precision Medicine Initiative Cohort Program to enroll 1 million or more participants in a national research effort designed to find better ways to prevent and treat disease based on lifestyle, environment and genetics.

11 Jul 2016

NIH selects VUMC to play foundational role in PMI Cohort Program

Vanderbilt University Medical Center has been chosen by the National Institutes of Health to be the Data and Research Support Center for the Precision Medicine Initiative Cohort Program, a landmark study of genetic, environmental and lifestyle factors affecting the health of a million or more people, federal officials have announced.

11 Jul 2016

Study shows hamstring injury prevention programs can help reduce lost play time in baseball

Creating a program to prevent hamstring injuries in minor league and major league baseball players might be a possibility say researchers presenting their work today at the American Orthopaedic Society of Sports Medicine's Annual Meeting in Colorado Springs, CO.

11 Jul 2016

Scientists develop new online open-access data tool to improve drug safety

A new online open-access database has been developed by scientists to allow the clinical responses of more than 5 million patients to all FDA-approved drugs to be used to identify unexpected clinical harm, benefits and alternative treatment choices for individual patients, according to a study appearing July 8 in Nature Biotechnology.

10 Jul 2016

Scientists identify epigenetic alterations involved in autoinflammatory diseases

Researchers from the Chromatin and Disease group of the Bellvitge Biomedical Research Institute, led by Dr. Esteban Ballestar, have identified for the first time epigenetic alterations in autoinflammatory diseases, particularly in cryopyrin-associated periodic syndromes (CAPS).

8 Jul 2016

Negative illness perceptions influence coping and health outcomes in CKD patients

Research involving the University of Leicester has shown people who have chronic kidney disease (CKD) form pre-conceived beliefs about their illness which can impact their health.

8 Jul 2016

Transplant drug rapamycin may reduce nerve damage, neuropathic pain after spinal cord injury

New research in mice indicates that a drug commonly used to suppress the immune system in recipients of organ transplants may also reduce tissue damage and neuropathic pain after spinal cord injury. The findings are published in the Journal of Orthopaedic Research.

8 Jul 2016

Athletes may experience long-term brain changes after sports-related concussion

New research finds white matter changes in the brains of athletes six months after a concussion. The study will be presented at the Sports Concussion Conference in Chicago, July 8-10, hosted by the American Academy of Neurology, the world's leading authority on the diagnosis and management of sports-related concussion.

8 Jul 2016

New topical film patch can effectively close dermal wounds, reduce scarring

Currently there is no product available based on polymer film containing active molecules to accelerate dermal wound healing that also reduces the scar formation.

8 Jul 2016

Extra-coding RNA modulates neuronal DNA methylation patterns

The creation of memories in the brain involves addition or removal of methyl groups at precise spots on chromosomal DNA. But what controls the careful targeting of these neuronal DNA methylation dynamics?

8 Jul 2016

TSRI awarded $20 million for first year of precision medicine initiative cohort program

As part of the most ambitious medical research program in the history of American medicine, The Scripps Research Institute (TSRI) has received an initial award of $20 million for its role in a national precision medicine initiative, the National Institutes of Health (NIH) announced today.

8 Jul 2016

Chronic News and Research

Leukemia drug increases brain dopamine, lowers toxic proteins linked to Parkinson's or dementia

Prevalence of global diabetes has been vastly underestimated, say Monash researchers

Innovative organ donation program allows living donors to donate kidney in advance

Scientists discover new mechanism by which TNF protects against intracellular pathogens

Women who undergo axillary node surgery for breast cancer more likely to develop chronic pain

Study identifies new blood markers to accurately diagnose Gulf War Illness

Non-drug solutions for postpartum depression: an interview with Dr David Brock & Christopher Thatcher

Single dose of new molecule could protect the brain from cognitive impairments after mTBI

Thousands of volunteers join clinical trial to help transform early detection of diabetic eye disease

UChicago to help enroll 150,000 participants in President’s PMI Cohort Program

NIH selects VUMC to play foundational role in PMI Cohort Program

Study shows hamstring injury prevention programs can help reduce lost play time in baseball

Scientists develop new online open-access data tool to improve drug safety

Scientists identify epigenetic alterations involved in autoinflammatory diseases

Negative illness perceptions influence coping and health outcomes in CKD patients

Transplant drug rapamycin may reduce nerve damage, neuropathic pain after spinal cord injury

Athletes may experience long-term brain changes after sports-related concussion

New topical film patch can effectively close dermal wounds, reduce scarring

Extra-coding RNA modulates neuronal DNA methylation patterns

TSRI awarded $20 million for first year of precision medicine initiative cohort program

Industry Focus eBook - Cell biology (5th edition) eBook

Managing vibration in IVF laboratories

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

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