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Pilot program that includes video decision aids improves end-of-life care in Hawaii

A program encouraging physicians and other providers to discuss with patients their preferences regarding end-of-life care significantly increased the documented incidence of such conversations and the number of patients with late-stage disease who were discharged to hospice.

24 May 2016

Existing MCI screening tools result in more than 7% false-negative error rate, study finds

Mild cognitive impairment (MCI) is a slight but noticeable and measurable decline in cognitive abilities, such as remembering names or a list of items. While changes may not be severe enough to disrupt daily life, a clinical diagnosis of MCI indicates an increased risk of eventually developing Alzheimer's disease or another type of dementia.

24 May 2016

National Cancer Moonshot initiative needs to target proteins that drive cancer

The National Cancer Moonshot initiative needs to move beyond genomics to target the proteins that are driving cancer, according to an Inova Health System and George Mason University collaborative paper published Thursday in the American Association for Cancer Research.

24 May 2016

Telephone-based intervention helps reduce menopause-related insomnia, hot flashes

Chatting on the phone with a "sleep coach" and keeping a nightly sleep diary significantly improve sleep quality and reduce insomnia in women through all stages of menopause, according to a new study published today in JAMA Internal Medicine.

24 May 2016

Study highlights disparities in care for disadvantaged children with traumatic brain injuries

Children who suffer traumatic brain injuries can face a difficult road to recovery, requiring services such as physical therapy and mental health treatment for months or years to get their young lives back on track.

24 May 2016

School obesity prevention program helps seventh graders lose weight over long-term period

A five-week obesity prevention program for seventh grade students in Southern California helped obese students lose weight over a long-term period, according to a new study from the RAND Corporation, Boston Children's Hospital, Harvard Medical School and the Los Angeles Unified School District.

24 May 2016

Personalized DXM-loaded leukosomes may help treat inflammation

Nanosized Trojan horses created from a patient's own immune cells have successfully treated inflammation by overcoming the body's complex defense mechanisms, perhaps leading to broader applications for treating diseases characterized by inflammation, such as cancer and cardiovascular diseases.

24 May 2016

Study shows endoscopist knowledge of positive Cologuard result may enhance colonoscopy quality

An endoscopist's knowledge of a positive Cologuard test improves colonoscopy performance, according to a poster presentation at last week's Digestive Disease Week conference.

24 May 2016

HbA1C test can effectively detect hidden diabetes among hyperglycemia patients

A retrospective review of medical records found the HbA1C test, commonly used to diagnose and manage diabetes, can effectively detect hidden disease among hospital patients with hyperglycemia, commonly known as high blood sugar.

24 May 2016

Clinical study examines efficacy of new interactive software game to treat pediatric food allergies

Elizabeth McQuaid, Ph.D., a staff psychologist from the Bradley Hasbro Children's Research Center, is leading the Phase II trial of an interactive software game developed to help children with food allergies better manage allergy symptoms, social situations and proper food avoidance.

23 May 2016

Studies explore possible link between pediatric cancer and light therapy for newborn jaundice

Two new studies raise enough questions about a possible link between childhood cancer and light therapy for newborn jaundice that clinicians should exercise caution in prescribing the treatment for infants whose jaundice is likely to resolve on its own, a pediatric oncologist from Dana-Farber/Boston Children's Cancer and Blood Disorders Center argues in an editorial published today by the journal Pediatrics.

23 May 2016

Investigational drug abemaciclib shows durable clinical activity for variety of cancer types

The investigational anticancer therapeutic abemaciclib, which targets CDK4 and CDK6, showed durable clinical activity when given as continuous single-agent therapy to patients with a variety of cancer types, including breast cancer, non-small cell lung cancer (NSCLC), glioblastoma, and melanoma, according to results from a phase I clinical trial.

23 May 2016

Researchers developing web-based, decision-support tool for osteoarthritis patients

Researchers at UMass Medical School are developing a web-based, decision-support tool for osteoarthritis patients that will provide individualized, evidence-based information in real time to guide optimal knee and hip care, including joint replacement.

23 May 2016

Researchers urge specific guidelines for fertility, sexual function counseling in at-risk pediatric patients

The drugs and therapies used to treat medical conditions often come with side effects. Doctors, pharmacists and other health care professionals strive to be sure we are made aware.

20 May 2016

New research looks at conversations that take place among selected parenting groups on Facebook

A study of conversations among pregnant women and new mothers on Facebook has highlighted a need for health professionals to provide clear direction on where new parents and pregnant women can access reliable and evidence based information about medicines.

20 May 2016

Older, frail hypertensive adults could benefit from intensive lowering of blood pressure

Adults with hypertension who are age 75 years and older, including those who are frail and with poor overall health, could benefit from lowering their blood pressure below current medical guidelines.

20 May 2016

SeeKD targeted screening program helps early detection of CKD risk in Canadians

A screening program for chronic kidney disease (CKD) initiated in Canada has successfully identified a high proportion of individuals with risk factors for CKD as well as many with unrecognized CKD.

20 May 2016

Combined public health intervention could help manage CKD in developing countries

A simple and inexpensive public health intervention helped prevent many cases of chronic kidney disease (CKD) in Pakistan. The intervention, which is described in a study in the Clinical Journal of the American Society of Nephrology, will be especially helpful for protecting the kidney health of people living in developing countries.

20 May 2016

Microglia plays vital role in reducing effects of cocaine in the brain

A type of brain cell known as microglia plays a key role in reducing the effects of cocaine in the brain, according to a major study by a team from the Research Institute of the McGill University Health Centre in Montreal.

20 May 2016

Gene editing technology helps excise segment of HIV-1 DNA from genomes of living animals

Using gene editing technology, researchers at the Lewis Katz School of Medicine at Temple University have, for the first time, successfully excised a segment of HIV-1 DNA - the virus responsible for AIDS - from the genomes of living animals.

20 May 2016

Health Care News and Research

Pilot program that includes video decision aids improves end-of-life care in Hawaii

Existing MCI screening tools result in more than 7% false-negative error rate, study finds

National Cancer Moonshot initiative needs to target proteins that drive cancer

Telephone-based intervention helps reduce menopause-related insomnia, hot flashes

Study highlights disparities in care for disadvantaged children with traumatic brain injuries

School obesity prevention program helps seventh graders lose weight over long-term period

Personalized DXM-loaded leukosomes may help treat inflammation

Study shows endoscopist knowledge of positive Cologuard result may enhance colonoscopy quality

HbA1C test can effectively detect hidden diabetes among hyperglycemia patients

Clinical study examines efficacy of new interactive software game to treat pediatric food allergies

Studies explore possible link between pediatric cancer and light therapy for newborn jaundice

Investigational drug abemaciclib shows durable clinical activity for variety of cancer types

Researchers developing web-based, decision-support tool for osteoarthritis patients

Researchers urge specific guidelines for fertility, sexual function counseling in at-risk pediatric patients

New research looks at conversations that take place among selected parenting groups on Facebook

Older, frail hypertensive adults could benefit from intensive lowering of blood pressure

SeeKD targeted screening program helps early detection of CKD risk in Canadians

Combined public health intervention could help manage CKD in developing countries

Microglia plays vital role in reducing effects of cocaine in the brain

Gene editing technology helps excise segment of HIV-1 DNA from genomes of living animals

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