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OHSU professor conducts clinical trial with artificial pancreas using Xeris' liquid glucagon

Xeris Pharmaceuticals, Inc., a specialty pharmaceutical company leveraging its novel technology platforms to develop and commercialize ready-to-use injectable and infusible drug formulations, announced today that Jessica Castle, M.D., an associate professor of medicine in the OHSU School of Medicine and OHSU Harold Schnitzer Diabetes Health Center in Portland, Oregon, is conducting a clinical trial with a dual-hormone artificial pancreas using Xeris' ready-to-use liquid glucagon to evaluate a new closed-loop algorithm.

17 Aug 2018

ACR expresses concerns on step therapy in a recent meeting with HSS Secretary

Yesterday, the American College of Rheumatology met with U.S. Department of Health and Human Services Secretary Alex Azar for a productive discussion about the rheumatology community's concerns with a new policy that will allow Medicare Advantage plans to utilize step therapy in Medicare Part B.

17 Aug 2018

New CRISPR technology may help eliminate mutated gene sequence

In a new study in cells, University of Illinois researchers have adapted CRISPR gene-editing technology to cause the cell's internal machinery to skip over a small portion of a gene when transcribing it into a template for protein building.

17 Aug 2018

New project to combat DMD-related fibrosis receives major funding boost

Duchenne muscular dystrophy is one of the most common congenital diseases in the world, affecting one in 3,500 Canadian males. DMD is caused by mutations in the dystrophin gene that results in progressive muscle degeneration and there are currently no effective treatments for DMD.

17 Aug 2018

Federal advisory group publishes recommendations on prevention of acute, chronic pain

A University of Texas at Arlington professor led a federal advisory group that has published its recommendations on the prevention of acute and chronic pain to the Federal Research Pain Strategy, an interagency committee that oversees the government's long-term strategic plan to support pain research.

17 Aug 2018

Statins may improve conditions of people with rare lung disease

In the first study of its kind, researchers have found that cholesterol-lowering statins may improve the conditions of people with a rare lung disease called autoimmune pulmonary alveolar proteinosis. The research also suggested that two new tests could help diagnose the condition.

17 Aug 2018

$New algorithm helps identify and manage diabetic patients at increased fracture risk$

New algorithm helps identify and manage diabetic patients at increased fracture risk

Fragility fractures are a serious yet neglected complication of both type 1 and type 2 diabetes, with increased risk of fragility fractures in people with diabetes extending across the life span.

17 Aug 2018

Seeking solutions to treat scleroderma

It begins with cold hands. Not just put-on-some-gloves cold. Instead, the fingers overreact to cold by turning white or blue and may become numb or tingly.

17 Aug 2018

Seattle Children's opens new clinic to provide convenient access to pediatric specialty care services

Seattle Children's today announced the opening of its newest regional clinic, Seattle Children's North Clinic, which will provide convenient access to pediatric specialty care services for families in north King, Snohomish, Whatcom and Skagit counties.

16 Aug 2018

Researchers develop molecular matrix that delivers healing stem cells to injured elderly muscles

A car accident leaves an aging patient with severe muscle injuries that won't heal. Treatment with muscle stem cells from a donor might restore damaged tissue, but doctors are unable to deliver them effectively. A new method may help change this.

16 Aug 2018

Trial shows PARP inhibitor as novel treatment option for patients with advanced breast cancers

In a randomized, Phase III trial led by researchers at The University of Texas MD Anderson Cancer Center, the PARP inhibitor talazoparib extended progression-free survival (PFS) and improved quality-of-life measures over available chemotherapies for patients with metastatic HER2-negative breast cancer and mutations in the BRCA1/2 genes.

16 Aug 2018

New HIV therapy suppresses viral replication and increases immune cells in drug-resistant patients

In a study, a new HIV drug reduced viral replication and increased immune cells in individuals with advanced, drug-resistant HIV infection. Used in combination with existing HIV medications, the drug is a promising strategy for patients who have run out of effective treatment options, the researchers said.

16 Aug 2018

Digital psychiatric therapy can 'rewire' the brain in children with ADHD, study shows

ATENTIV, LLC, pioneers in digital therapies for Attention Deficit/Hyperactivity Disorder and other cognitive disorders, today announced the publication of a recently completed brain imaging study using the ATENTIVmynd Technology platform.

15 Aug 2018

Preventing ACL injuries in high school athletes

It's not an uncommon scenario. An athlete is sailing through the air or making a quick turn when all of a sudden he or she hears a "pop" in the knee. An athlete who experiences this followed by sudden pain and swelling often receives the much-feared diagnosis of an anterior cruciate ligament tear.

15 Aug 2018

Study shows efficacy, safety of AAV5-based gene therapy to treat sheep model of achromatopsia

A study of a large animal model of achromatopsia caused by a mutation in the CNGA3 gene that was treated with a single injection of CNGA3 gene therapy delivered using an AAV5 vector revealed findings reported long-term follow-up findings that show promise for the efficacy and safety of this therapeutic approach.

15 Aug 2018

Therapy News and Research

OHSU professor conducts clinical trial with artificial pancreas using Xeris' liquid glucagon

ACR expresses concerns on step therapy in a recent meeting with HSS Secretary

New CRISPR technology may help eliminate mutated gene sequence

New project to combat DMD-related fibrosis receives major funding boost

Federal advisory group publishes recommendations on prevention of acute, chronic pain

Statins may improve conditions of people with rare lung disease

New algorithm helps identify and manage diabetic patients at increased fracture risk

Seeking solutions to treat scleroderma

Seattle Children's opens new clinic to provide convenient access to pediatric specialty care services

Researchers develop molecular matrix that delivers healing stem cells to injured elderly muscles

Trial shows PARP inhibitor as novel treatment option for patients with advanced breast cancers

New HIV therapy suppresses viral replication and increases immune cells in drug-resistant patients

Digital psychiatric therapy can 'rewire' the brain in children with ADHD, study shows

Preventing ACL injuries in high school athletes

Study shows efficacy, safety of AAV5-based gene therapy to treat sheep model of achromatopsia

Ablating the mutant p53 gene in mice with colorectal cancer inhibits tumor growth

New model of genetically engineered immune cells may help fight solid tumors

Researchers identify way to grow immune cells at large scale for preventing cancer reoccurrence

Researchers move closer to finding potential soft spot in drug-resistant tuberculosis

Seven activities that prevent you from getting quality sleep during summer

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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