Antibody News and Research

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An antibody is a blood protein that is produced in response to and counteracts an antigen. Antibodies are produced in response to disease and help the body fight against the particular disease. In this way, antibodies help the body develop an immunity to disease.

Tulane receives up to $16 million to move nasal pneumonia vaccine from the lab to clinical trials

The National Institute of Allergy and Infectious Diseases awarded an up to $16 million contract to Tulane University to bring to phase one clinical trial a nasal spray vaccine university researchers invented to thwart antibiotic-resistant Klebsiella pneumoniae, a leading cause of pneumonia.

24 Mar 2023

Researchers discover a new switching point that regulates hemostasis and thrombosis

The glycoprotein V of the blood platelets is an important switch point for hemostasis and thrombus formation. This new finding could have great clinical potential.

24 Mar 2023

Antibodies produced by newly developed mRNA vaccines are transferred from pregnant rabbits to offspring

Newly developed mRNA vaccines against Zika virus and HIV-1 produced strong antibody responses that transferred from pregnant rabbits to their offspring, researchers report March 24th in the journal Molecular Therapy.

24 Mar 2023

Candidate hepatitis C mRNA vaccine induces protective immunity in animal model

In a recent study published in the npj vaccines journal, researchers assessed the immune protection elicited by messenger ribonucleic acid (mRNA) vaccines delivering Hepatitis C virus (HCV) E1 and modified E2.

23 Mar 2023

Monovalent vs. bivalent vaccines – Which is more effective against SARS-CoV-2?

In a recent study posted to the medRxiv* preprint server, researchers in France compared the efficacy of Pfizer-BioNTech Original/BA.4-5 bivalent vaccine compared to messenger ribonucleic acid (mRNA) Original (ancestral) monovalent vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

22 Mar 2023

Dampened mucosal response against SARS-CoV-2 in pregnant individuals

In a recent study posted to the medRxiv* preprint server, researchers examined associations between coronavirus disease 2019 (COVID-19) outcomes and mucosal antibody responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and viral RNA levels in pregnant individuals.

22 Mar 2023

SARS-CoV-2 infection enhances vaccine-induced immunological memory against spike protein

Researchers assess SARS-CoV-2 spike protein-specific immunological memory among unvaccinated and vaccinated convalescents.

22 Mar 2023

Novel subset of memory B cells predicts long-lived antibody responses to influenza vaccination

Memory B cells play a critical role to provide long-term immunity after a vaccination or infection. In a study published in the journal Immunity, researchers describe a distinct and novel subset of memory B cells that predict long-lived antibody responses to influenza vaccination in humans.

22 Mar 2023

Disruption of the FcRn–IgG interaction may make AAV-based gene therapies effective

The use of a monoclonal antibody that reduced circulating IgG levels, led to a decrease in preexisting neutralizing antibodies (NAbs) to adeno-associated virus (AAV).

22 Mar 2023

Tetravalent COVID vaccine provides broad antibody responses against SARS-CoV-2 variants in animal model

In a recent study posted to the bioRxiv* preprint server, researchers in Italy and the United States evaluated the efficacy and immunogenicity of an adjuvanted tetravalent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein subunit 1 (S1) COVID-19 vaccine.

21 Mar 2023

Researchers identify the cellular glitches underlying a rare genetic disorder

The cellular glitches underlying a rare genetic disorder called activated PI3K Delta syndrome 2 (APDS2) have been identified by researchers at the Garvan Institute of Medical Research. The disorder is caused by genetic variations that disrupt immune cell signaling through a protein called PI3K.

21 Mar 2023

Snapping at new biotech breakthroughs with Gator Pro

In this interview, we speak to Subodh Nimkar, Marketing Director at Gator Bio, about their latest technology, Gator Pro which allows for fast, reliable, and high-quality data.

From Gator Bio, Inc. 21 Mar 2023

Childhood common colds help protect against COVID-19

In a recent study published in the Proceedings of the National Academy of Sciences, researchers assessed the association between cross-reactive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) CD4+ T cells generation and age.

20 Mar 2023

SARS-CoV-2 infection damages the CD8+ T cell response to vaccination

The magnitude and quality of a key immune cell's response to vaccination with two doses of the Pfizer-BioNTech COVID-19 vaccine were considerably lower in people with prior SARS-CoV-2 infection compared to people without prior infection, a study has found.

20 Mar 2023

H5N1 avian influenza found in stranded harbor porpoise

In a recent study published in the United States (U.S.) Centers for Disease Control and Prevention (CDC) journal Emerging Infectious Diseases, researchers from Sweden described the detection of the hemagglutinin type 5 and neuraminidase type 1 (H5N1) avian influenza virus in a stranded harbor porpoise, indicating a potential spillover of this highly pathogenic avian influenza virus into cetacean species.

20 Mar 2023

Inadequate sleep associated with lower vaccine-induced humoral immunity

Researchers assess the association between the duration of sleep and humoral responses to vaccination.

19 Mar 2023

Novel therapeutic eradicates gastric cancer in treated mice

A novel cancer therapeutic, combining antibody fragments with molecularly engineered nanoparticles, permanently eradicated gastric cancer in treated mice, a multi-institutional team of researchers found.

17 Mar 2023

Does vitamin D play an anti-viral role against SARS-CoV-2?

Researchers screened various compounds for anti-viral properties against SARS-CoV-2.

17 Mar 2023

Anti-Omicron antibodies are induced by hypermutation with ancestral BNT162b2 COVID vaccine

Scientists from the Republic of Korea have analyzed B-cell receptor repertoires induced by an mRNA-based coronavirus disease 2019 (COVID-19) vaccine and found that somatic hypermutations in B-cell receptor heavy chain are responsible for broadening its specificity for unexposed antigens.

16 Mar 2023

Monoclonal antibody-based blocking ELISA for SARS-CoV-2 detection in animals

In a recent study posted to the bioRxiv* preprint server, researchers in the United States described a blocking enzyme-linked immunosorbent assay (ELISA) to identify severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exposure in animals.

16 Mar 2023