Immune Response News and Research

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Mouse study offers clues to developing an effective vaccine for Klebsiella bacteria

A mouse study at Washington University School of Medicine in St. Louis points to data that could be key to developing an effective vaccine for the bacterium Klebsiella pneumoniae.

18 May 2023

Weekend catch-up sleep may minimize the risk of hyperuricemia in postmenopausal women

Sleep deprivation, especially common during postmenopause, has been linked with a number of health problems, including hyperuricemia (elevated serum uric acid), which can often lead to gout and other life-threatening conditions such as heart disease.

17 May 2023

Study establishes a mechanistic link between obesity and oral cancer immune escape

A team from the University of Michigan Rogel Cancer Center and School of Dentistry, led by Yu Leo Lei, D.D.S., Ph.D., have identified a mechanism in mice for how obesity affects some oral cancers' ability to escape from the immune system.

16 May 2023

"Smart" sutures can detect inflammation and release drugs

Inspired by sutures developed thousands of years ago, MIT engineers have designed "smart" sutures that can not only hold tissue in place, but also detect inflammation and release drugs.

16 May 2023

Machine learning reveals sex-specific Alzheimer's risk genes

Research explores sex-specific gene associations in Alzheimer's disease using a machine-learning approach. It reveals immune response pathways in both sexes and stress-response pathways in males, highlighting potential biomarkers and therapeutic targets for personalized treatments.

16 May 2023

Mast cells play a crucial role in the development of chronic myeloid leukemia

Chronic myeloid leukemia (CML) is a type of blood cancer that arises from malignant changes in blood-forming cells of the bone marrow.

16 May 2023

Cancer patients can initiate SARS-CoV-2 vaccination three months after bone marrow transplant

Patients with cancer whose immune systems are being supported or rebuilt by bone marrow transplantation should begin receiving vaccines for protection against SARS-CoV-2 three months post-transplant, according to a large, prospective, observational study led collaboratively by the Center for International Blood and Marrow Transplant Research, the Blood & Marrow Transplant Clinical Trials Network and Fred Hutchinson Cancer Center.

16 May 2023

Can beer intake improve heart health following oxidative injury?

Researchers examined the impact of antioxidants found in fermented beverages on tissue transcriptomics.

16 May 2023

Clinical trial of a combination treatment shows great promise for patients with glioblastoma

A new international study published in Nature Medicine and presented as a late-breaking abstract at the American Association of Neurological Surgeons annual conference, shows great promise for patients with glioblastoma.

15 May 2023

Phase 1 trial of experimental universal influenza vaccine begins enrolling volunteers

A clinical trial of an experimental universal influenza vaccine developed by researchers at the National Institute of Allergy and Infectious Diseases' (NIAID) Vaccine Research Center (VRC), part of the National Institutes of Health, has begun enrolling volunteers at Duke University in Durham, North Carolina.

15 May 2023

Combination approach is safe, improves survival outcomes in a subset of glioblastoma patients

Intratumoral delivery of an engineered oncolytic virus (DNX-2401) targeting glioblastoma (GBM) cells combined with subsequent immunotherapy was safe and improved survival outcomes in a subset of patients with recurrent GBM, according to results from a multi-institutional Phase I/II clinical trial co-led by researchers at The University of Texas MD Anderson Cancer Center and the University of Toronto.

15 May 2023

SARS-CoV-2 variants show altered glycan processing

Researchers examine spike-protein trimers from SARS-CoV-2 variants to compare the N (asparagine)-glycan landscape.

15 May 2023

Using an intracellular toolkit to map organelle bio-geography in stem cells

Organelles – the bits and pieces of RNA and protein within a cell – play important roles in human health and disease, such as maintaining homeostasis, regulating growth and aging, and generating energy.

12 May 2023

Could personalized neoantigen vaccines prevent the recurrence of pancreatic cancer and increase patient survival?

Researchers conducted a phase I clinical trial of a personalized mRNA neoantigen vaccine.

12 May 2023

Analyzing impact of phospholipase D on the host immune response to A. fumigatus infection

Announcing a new article publication for Zoonoses journal. Aspergillus fumigatus infection in the lungs is accompanied by the recruitment of innate immune cells, phagocytosis, and the release of inflammatory factors.

11 May 2023

Adenovirus and mRNA COVID vaccines differ in 6-month antibody durability

Research compares the durability of neutralizing antibody responses among recipients of three different COVID-19 vaccines (BNT162b2, mRNA-1273, and Ad26.COV2.S) over a period of 6 months.

11 May 2023

Protein inhibition could offer new strategies for treating severe asthma

Inhibiting a protein on the surface of immune cells could offer new strategies for treating severe asthma, Cleveland Clinic researchers found.

10 May 2023

Rising tide of chronic disease can be traced to impaired salugenesis, incomplete healing

In medicine and science, the term "pathogenesis" describes the origin and development of disease. There is not, however, a broadly accepted term to describe the other half of the equation: the process of healing and recovery.

10 May 2023

Silenced p16 gene can drive colorectal cancer progression

Colorectal cancer is the fourth most common and second deadliest cancer. How colorectal cancer develops is not well understood, but a team led by researchers at Baylor College of Medicine reports in the Journal of Experimental & Clinical Cancer Research that silencing the gene p16, even though the DNA itself does not change, can drive colorectal cancer progression in animal models.

10 May 2023

UCF researcher develops a new, more precise treatment for acute respiratory viral infections

A University of Central Florida College of Medicine researcher has developed a new, more precise treatment for a major cause of illness around the world each year - acute respiratory viral infections.

9 May 2023

Immune Response News and Research

Mouse study offers clues to developing an effective vaccine for Klebsiella bacteria

Weekend catch-up sleep may minimize the risk of hyperuricemia in postmenopausal women

Study establishes a mechanistic link between obesity and oral cancer immune escape

"Smart" sutures can detect inflammation and release drugs

Machine learning reveals sex-specific Alzheimer's risk genes

Mast cells play a crucial role in the development of chronic myeloid leukemia

Cancer patients can initiate SARS-CoV-2 vaccination three months after bone marrow transplant

Can beer intake improve heart health following oxidative injury?

Clinical trial of a combination treatment shows great promise for patients with glioblastoma

Phase 1 trial of experimental universal influenza vaccine begins enrolling volunteers

Combination approach is safe, improves survival outcomes in a subset of glioblastoma patients

SARS-CoV-2 variants show altered glycan processing

Using an intracellular toolkit to map organelle bio-geography in stem cells

Could personalized neoantigen vaccines prevent the recurrence of pancreatic cancer and increase patient survival?

Analyzing impact of phospholipase D on the host immune response to A. fumigatus infection

Adenovirus and mRNA COVID vaccines differ in 6-month antibody durability

Protein inhibition could offer new strategies for treating severe asthma

Rising tide of chronic disease can be traced to impaired salugenesis, incomplete healing

Silenced p16 gene can drive colorectal cancer progression

UCF researcher develops a new, more precise treatment for acute respiratory viral infections

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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