Preclinical News and Research

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Could a mushroom-derived product be the future of lung cancer prevention?

Researchers find that a mushroom-derived product, GLSF, shows promise in reducing lung toxicity and tumor development induced by tobacco smoke carcinogens in mice. The study opens the door for future clinical trials, potentially offering a natural preventive measure against lung cancer.

26 Sep 2023

Radiation therapy combined with two types of immunotherapy could be effective against cold tumors

Researchers at Weill Cornell Medicine have discovered that radiation therapy combined with two types of immunotherapy - one that boosts T cells, and another that boosts dendritic cells - can control tumors in preclinical models of triple negative breast cancer, a cancer type that's typically resistant to immunotherapy alone.

25 Sep 2023

Research presents new approach to identify therapeutic targets for human diseases associated with protein phase separation

Recent research demonstrates that protein phase separation (PPS) is widely present in cells and drives a variety of important biological functions.

25 Sep 2023

Weill Cornell Medicine receives NIH grant to lead a national contraceptive research center

Weill Cornell Medicine has received a three-year, nearly $6 million grant to lead one of three national contraceptive research centers.

21 Sep 2023

Study sheds light on the cause of craniosynostosis in infants

Craniosynostosis, the premature fusion of the top of the skull in infants, is caused by an abnormal excess of a previously unknown type of bone-forming stem cell, according to a preclinical study led by researchers at Weill Cornell Medicine.

21 Sep 2023

USC develops innovative system for conducting preclinical research on potential stroke treatments

To test new stroke treatments, a research team from the Keck School of Medicine of USC develops a more rigorous system for conducting preclinical research that could lead to more successful clinical trials.

20 Sep 2023

New near-infrared activated photo-oxidants kill cancer cells without oxygen

A research team led by scientists from City University of Hong Kong (CityU) has achieved a significant breakthrough by inventing a new class of near-infrared-activated photo-oxidants that can effectively kill cancer cells without requiring oxygen.

20 Sep 2023

Does losing your sense of purpose signal the onset of cognitive decline?

A recent study in JAMA Network Open explores how an individual's sense of purpose in life changes before and after the onset of cognitive impairment, using data from two large, longitudinal studies. The research finds that while there are modest declines in purpose before cognitive decline, these reductions become significantly greater after cognitive impairment sets in, suggesting that maintaining a sense of purpose could be crucial for cognitive health.

19 Sep 2023

Research demonstrates a double-acting mechanism for fighting triple-negative breast cancer

Zachary Schug, Ph.D., assistant professor in the Molecular and Cellular Oncogenesis Program of the Ellen and Ronald Caplan Cancer Center at The Wistar Institute, has published a new paper in the journal Nature Cancer.

19 Sep 2023

Researchers identify new blood marker for dopamine system damage

The marker in question is called DOPA decarboxylase (DCC). In the current study, DCC was found to be elevated in individuals with Parkinson's disease as well as in people with other diseases that result in dopamine deficiency in the brain. However, the marker was normal in other brain diseases such as Alzheimer's disease. The researchers even noticed that DCC was elevated in individuals with Parkinson's many years before they developed any symptoms.

19 Sep 2023

Nano-based cancer therapies may be less effective in younger patients, finds study

Researchers at The University of Texas MD Anderson Cancer Center have discovered that certain nano-based cancer therapies may be less effective in younger patients, highlighting the need for further investigation into the impact of aging on the body's ability to respond to treatment.

19 Sep 2023

Cancer drug could play a role in limiting the damaging effects of lung disease in COVID-19 patients

A cancer drug could play an important role in limiting the damaging effects of lung disease in COVID-19 patients, thanks to new research at Hudson Institute of Medical Research.

19 Sep 2023

Breast milk proteins linked to abundance of beneficial bacteria in infants

More than 320 million years of mammalian evolution has adapted breast milk to meet all the physiological needs of babies: it contains not only nutrients, but also hormones, antimicrobials, digestive enzymes, and growth factors.

15 Sep 2023

Nuvectis launches Phase 1a dose escalation clinical trial of new cancer drug

Clinical trials have begun for a drug candidate for hard-to-treat cancers, discovered at the University of Edinburgh and licensed by US biopharmaceutical company Nuvectis Pharma, Inc.

15 Sep 2023

New nano-thin superbug-slaying material could revolutionize wound healing

Researchers have invented a nano-thin superbug-slaying material that could one day be integrated into wound dressings and implants to prevent or heal bacterial infections.

14 Sep 2023

Oral SARS-CoV-2 vaccine shows promise in monkeys

A new paper in Biology Methods and Protocols, published by Oxford University Press, indicates that researchers studying SARS-CoV-2 may have developed new methods to administer vaccines orally, which would be both easier to administer and more effective at combatting illnesses.

13 Sep 2023

Ketogenic dietary intervention may inhibit onset and progression of neuroendocrine tumors

Cerba Healthcare to acquire Canadian contract research laboratory Cirion Biopharma Research to expand bioanalytical capabilities and shorten time-to-deploy complex clinical trials

Cerba HealthCare, a leading global player in medical diagnosis, today announced it has acquired CIRION BIOPHARMA RESEARCH INC

From Cerba Research 11 Sep 2023

Preclinical News and Research

Could a mushroom-derived product be the future of lung cancer prevention?

Radiation therapy combined with two types of immunotherapy could be effective against cold tumors

Research presents new approach to identify therapeutic targets for human diseases associated with protein phase separation

Weill Cornell Medicine receives NIH grant to lead a national contraceptive research center

Study sheds light on the cause of craniosynostosis in infants

USC develops innovative system for conducting preclinical research on potential stroke treatments

New near-infrared activated photo-oxidants kill cancer cells without oxygen

Does losing your sense of purpose signal the onset of cognitive decline?

Research demonstrates a double-acting mechanism for fighting triple-negative breast cancer

Researchers identify new blood marker for dopamine system damage

Nano-based cancer therapies may be less effective in younger patients, finds study

Cancer drug could play a role in limiting the damaging effects of lung disease in COVID-19 patients

Breast milk proteins linked to abundance of beneficial bacteria in infants

Nuvectis launches Phase 1a dose escalation clinical trial of new cancer drug

New nano-thin superbug-slaying material could revolutionize wound healing

Oral SARS-CoV-2 vaccine shows promise in monkeys

Ketogenic dietary intervention may inhibit onset and progression of neuroendocrine tumors

Study reveals a new potential treatment approach for glioblastoma

Oxford University study administers first-ever vaccine against Crimean-Congo hemorrhagic fever

Cerba Healthcare to acquire Canadian contract research laboratory Cirion Biopharma Research to expand bioanalytical capabilities and shorten time-to-deploy complex clinical trials

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