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Leukemia patients currently ineligible for targeted therapy may benefit from new drugs

Patients with an aggressive form of leukemia, currently ineligible for any type of targeted therapy, may in fact benefit from some of these new drugs, according to new research by Queen Mary University of London.

9 Jan 2018

Researchers develop drug that supports cellular traffic jam theory in ALS/FTD

Neurodegeneration in ALS/FTD may be caused by TDP-43 aggregation in the cytoplasm, causing cellular traffic jams. The trial drug can sequester TDP-43.

9 Jan 2018

Researchers discover cluster of multidrug-resistant tuberculosis pathogens

Between February and November 2016, the Institute of Medical Microbiology at the University of Zurich discovered a multidrug-resistant Mycobacterium tuberculosis in eight refugees arriving in Europe from the Horn of Africa.

9 Jan 2018

Her sister’s keeper: Caring for a sibling with mental illness

When sisters Jean and Ruby were growing up in Harlem, they invented a game of make-believe called "Eartha." The little girls would put on their prettiest dresses and shiniest shoes and sit down to tea as grown-up ladies. They discussed details of their hoped-for husbands and children, and all the exciting things they would do together.

9 Jan 2018

Common gene test to predict breast cancer recurrence may not be cost-effective

The most commonly used gene expression profile test used to help predict breast cancer recurrence may not be as cost-effective as once thought, say a team of researchers led by Georgetown Lombardi Comprehensive Cancer Center.

9 Jan 2018

Survival strategy of mRNAs during sugar deficiency in the cell

If a cell runs low on sugar, it stores certain messenger RNAs in order to prolong its life. As a research group at the Biozentrum of the University of Basel has now discovered, the protein Puf5p determines whether individual messenger RNAs will be stored or degraded when sugar levels are low.

9 Jan 2018

Oncologists discover cell type that gives rise to soft tissue cancer in children

St. Jude Children's Research Hospital oncologists have discovered the cell type that gives rise to rhabdomyosarcoma, the most prevalent soft tissue cancer in children.

8 Jan 2018

WPI professor receives Smith Family Foundation grant to explore biology of cancer cells

Amity Manning, assistant professor of biology and biotechnology, has received a three-year, $300,000 award from the Smith Family Awards Program for Excellence in Biomedical Research.

8 Jan 2018

Researchers discover mutations in a gene related to obesity

Researchers have discovered mutations in a gene related to obesity, offering new treatment possibilities in the fight against the global epidemic.

8 Jan 2018

Polygenic risk score predicts early-onset heart disease risk

A risk score based on multiple genetic differences, or polygenic risk score, predicted significantly more cases of early-onset heart disease than standard tests for single genetic defects, according to new research in the American Heart Association's journal Circulation: Genomic and Precision Medicine.

8 Jan 2018

Sangamo and Pfizer partner for development of new zinc finger protein gene therapy to treat ALS

Sangamo Therapeutics, Inc. and Pfizer Inc. today announced a collaboration for the development of a potential gene therapy using zinc finger protein transcription factors (ZFP-TFs) to treat amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) linked to mutations of the C9ORF72 gene.

8 Jan 2018

Bielefeld scientists discover cause of initially unclear symptoms

The sequencing of the human genome has made it possible: nowadays scientists can discover potential disorders for which there are no known patients.

5 Jan 2018

Researchers pinpoint mechanism for conversion of white fat into brown fat

An international team of researchers led from Karolinska Institutet have, in experiments on mice, pinpointed a mechanism for the conversion of energy-storing white fat into energy-expending brown fat.

5 Jan 2018

Strategies to prevent and treat acute chest syndrome in children with sickle cell disease

Acute chest syndrome (ACS), a potentially severe lung complication of sickle cell disease, increases a child's risk of respiratory failure, chronic lung disease, and prolonged hospitalization if not recognized early and treated effectively.

5 Jan 2018

Genetic differences can influence efficiency of medicines

Medicines do not follow the one size fits all principle, because genetic differences can influence their efficiency.

5 Jan 2018

Researchers use genomic technologies to better understand risk factor for stomach cancer

A research team led by National University Health System and Duke-NUS Medical School has used genomic technologies to better understand intestinal metaplasia, a known risk factor for gastric (stomach) cancer.

5 Jan 2018

Specific bacteria in the intestines can improve response rate to cancer immunotherapy

In the Jan. 5, 2018 issue of Science, researchers from the University of Chicago Medicine show that specific strains of commensal bacteria – the swarms of microorganisms naturally dwelling in the intestines – can improve the response rate to immunotherapy for patients being treated for advanced melanoma.

5 Jan 2018

Genetic News and Research

Leukemia patients currently ineligible for targeted therapy may benefit from new drugs

Researchers develop drug that supports cellular traffic jam theory in ALS/FTD

Researchers discover cluster of multidrug-resistant tuberculosis pathogens

Her sister’s keeper: Caring for a sibling with mental illness

Common gene test to predict breast cancer recurrence may not be cost-effective

Survival strategy of mRNAs during sugar deficiency in the cell

Oncologists discover cell type that gives rise to soft tissue cancer in children

WPI professor receives Smith Family Foundation grant to explore biology of cancer cells

Researchers discover mutations in a gene related to obesity

Polygenic risk score predicts early-onset heart disease risk

Sangamo and Pfizer partner for development of new zinc finger protein gene therapy to treat ALS

Bielefeld scientists discover cause of initially unclear symptoms

Researchers pinpoint mechanism for conversion of white fat into brown fat

Strategies to prevent and treat acute chest syndrome in children with sickle cell disease

Genetic differences can influence efficiency of medicines

Researchers use genomic technologies to better understand risk factor for stomach cancer

Specific bacteria in the intestines can improve response rate to cancer immunotherapy

Researchers discover genetic mechanism for resistance to immunotherapy drugs

Study finds link between dietary sugar and increasing bacterial epidemics

Study provides insight into how early-stage breast cancer progresses to invasive ductal carcinoma

Genetics & Genomics - Second Edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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