Protein C News and Research

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Potential new therapy for progeria

Aging is a complex and natural process that affects all living organisms. As people age, normal biological processes are affecting, resulting in a decline in various organs and age-related conditions. Though aging is normal, some children affected by a disease called Progeria may age way faster than others.

18 Nov 2019

Cancer drug shows promise in treating metabolic syndrome

Metabolic syndrome is a group of health problems characterized by the presence of elevated blood pressure, increased levels of triglycerides, high blood sugar, excess body fat around the waist, and obesity. If it’s left untreated, it can increase the risk of heart disease, stroke, and type 2 diabetes. Usually, treating metabolic syndrome involves targeting individual risk factors and modifying lifestyle practices.

18 Nov 2019

Self-destructive mitochondria may set the stage for neurodegeneration in ALS

Northwestern Medicine scientists have discovered a new phenomenon in the brain that could explain the development of early stages of neurodegeneration seen in diseases such as ALS, which affects voluntary muscle movement such as walking and talking.

18 Nov 2019

High-protein diets may affect kidney health

A high-protein diet is believed to be healthy. It is suggested that it keeps you fit, helps you to lose fat and to retain lean muscle mass. Avoiding carbohydrates and substituting them with proteins has become a leading dogma for all those who care for their looks and health.

18 Nov 2019

BGU researchers discover gene that causes nighttime atrial fibrillation

Genetic studies spanning three generations of a Persian Jewish family by researchers at Ben-Gurion University of the Negev. have identified a gene that causes nighttime atrial fibrillation (AFib).

18 Nov 2019

Newly discovered cell involved in rheumatoid arthritis could serve as treatment target

Researchers have made a discovery about a class of cells involved in rheumatoid arthritis that could instigate new treatments.

18 Nov 2019

Experimental drug found to be effective at reducing bad cholesterol

Twice-yearly injections of an experimental cholesterol-lowering drug, inclisiran, were effective at reducing low-density lipoprotein (LDL) cholesterol, often called bad cholesterol, in patients already taking the maximum dose of statin drugs, according to data of the ORION-10 trial presented Saturday, Nov. 16, at the American Heart Association's Scientific Sessions 2019.

17 Nov 2019

Melbourne researchers find how MAIT cells identify and attack foreign invaders

Melbourne researchers have identified what makes a specialized immune cell, known as mucosal-associated invariant T (MAIT), cells boost their numbers and attack foreign invaders at the site of the infection.

15 Nov 2019

Study uncovers how the molecule-sorting station in our cells is formed and maintained

The cells in our body are workshops that continuously operate to produce and process substances to keep us going. When a substance enters a cell for processing, it is surrounded by a portion of the cell's outer membrane to form a sac.

15 Nov 2019

Mining 'darkest' parts of the genome in cancer cells yields gold

Mining the rich uncharted territory of the genome or genetic material of a cancer cell has yielded gold for Princess Margaret scientists: new protein targets for drug development against prostate cancer.

15 Nov 2019

Scientists reverse learning and memory deficits with drugs in animal model of Down syndrome

In a surprising finding using the standard animal model of Down syndrome (DS), scientists were able to correct the learning and memory deficits associated with the condition -- the leading genetic cause of cognitive disability and the most frequently diagnosed chromosomal disorder in the U.S. -- with drugs that target the body's response to cellular stresses.

15 Nov 2019

PhoreMost and Sentinel Oncology expand partnership to advance novel allosteric PLK1 inhibitor

PhoreMost Limited, the UK-based biopharmaceutical company dedicated to drugging ‘undruggable’ disease targets, and Sentinel Oncology, today announce an expansion of their collaboration to accelerate the progression of SOL686, a novel allosteric Polo-like kinase 1 (PLK1) inhibitor through preclinical development and IND enabling studies for the treatment of Glioma.

From PhoreMost 15 Nov 2019

Non-coding enhancer DNA may be key for identifying genetic risk in neurological conditions

One might think that the primary cause of most genetically linked diseases comes from mutations in coding DNA -- alterations in coding regions of the genome that can lead directly to changes in the expression of particular proteins important for a healthy body.

14 Nov 2019

Research explains why immunotherapy fails against prostate cancer bone metastases

Prostate cancer that spreads to the bone triggers the destruction of bone tissue that, in turn, thwarts the effectiveness of immune checkpoint inhibitors by blocking the development of T cells that are crucial to successful treatment, researchers from The University of Texas MD Anderson Cancer Center report in Cell.

14 Nov 2019

New treatment stops peanut allergy for 6 weeks with single dose

A small study published in the journal JCI Insight on November 14, 2019, suggests that antibody treatment could help people with severe allergy to peanuts eat a small amount of peanut-containing food just two weeks later, without any ill effects. This seems to show that this is a safe, fast and effective treatment for food allergy.

14 Nov 2019

Study sheds light on how Zika virus causes microcephaly in newborns

A new study led by researchers at Baylor College of Medicine revealed how in utero Zika virus infection can lead to microcephaly in newborns. The team discovered that the Zika virus protein NS4A disrupts brain growth by hijacking a pathway that regulates the generation of new neurons.

14 Nov 2019

Protein C News and Research

Potential new therapy for progeria

Cancer drug shows promise in treating metabolic syndrome

Self-destructive mitochondria may set the stage for neurodegeneration in ALS

High-protein diets may affect kidney health

BGU researchers discover gene that causes nighttime atrial fibrillation

Newly discovered cell involved in rheumatoid arthritis could serve as treatment target

Experimental drug found to be effective at reducing bad cholesterol

Melbourne researchers find how MAIT cells identify and attack foreign invaders

Study uncovers how the molecule-sorting station in our cells is formed and maintained

Mining 'darkest' parts of the genome in cancer cells yields gold

Scientists reverse learning and memory deficits with drugs in animal model of Down syndrome

PhoreMost and Sentinel Oncology expand partnership to advance novel allosteric PLK1 inhibitor

Non-coding enhancer DNA may be key for identifying genetic risk in neurological conditions

Research explains why immunotherapy fails against prostate cancer bone metastases

New treatment stops peanut allergy for 6 weeks with single dose

Study sheds light on how Zika virus causes microcephaly in newborns

Promising method to identify aggressive breast cancers that will respond to immunotherapy

Alzheimer's Association's funding enables expansion of aging study in longest running birth cohort

New technique enables the study of transporter proteins at a single-molecule level

Knocking out 'survival system' of cancer cells could improve effectiveness of melanoma treatment

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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