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Nuon Therapeutics advances NU1618 into phase 2b development for chronic hyperuricemia in gout patients

Nuon Therapeutics, Inc., a privately held, clinical stage biopharmaceutical company, announced that the company is advancing its lead program, NU1618, into phase 2b development for the treatment of chronic hyperuricemia in patients with gout. Nuon anticipates releasing topline data from a completed proof-of-principle, phase 2a study of NU1618 in the second quarter of 2010.

22 Apr 2010

Catabasis Pharmaceuticals to advance program targeting type 2 diabetes with $39.6 million Series A financing

Catabasis Pharmaceuticals, a biopharmaceutical company developing novel therapeutics for the treatment of inflammatory and metabolic diseases, today announced it has completed a $39.6 million Series A financing led by SV Life Sciences, Clarus Ventures, and MedImmune Ventures. Also participating in the round is Advanced Technology Ventures.

21 Apr 2010

Researchers detect link between alcohol consumption, cancer and aging

Researchers have detected a link between alcohol consumption, cancer and aging that starts at the cellular level with telomere shortening.

21 Apr 2010

Merck to market and distribute MBL's Td vaccine in the U.S.

MassBiologics of the University of Massachusetts Medical School and Merck & Co., Inc. announced today that they have entered into an agreement that provides Merck with exclusive rights to market and distribute MBL's tetanus and diphtheria toxoids adsorbed (Td) vaccine in the United States, with the exception of Massachusetts, where MBL will continue distributing the vaccine.

21 Apr 2010

A*STAR's BMRC and SIgN award grants for twelve research projects on infectious diseases and immunology

Twelve research projects on infectious diseases and immunology have been awarded grants by A*STAR's Biomedical Research Council (BMRC) and Singapore Immunology Network (SIgN) this year.

21 Apr 2010

Modest weight reduction reverses immune cell damage in obese people with diabetes

Australian scientists have shown for the first time that even modest weight loss reverses many of the damaging changes often seen in the immune cells of obese people, particularly those with Type 2 diabetes.

21 Apr 2010

Gene test predicts statins' effectiveness in reducing risk of colorectal cancer

A genetic test can help determine in which patients cholesterol-lowering statin drugs might have the most benefit in also reducing the risk of colorectal cancer, a new study from researchers at the University of Michigan Comprehensive Cancer Center finds.

21 Apr 2010

DiscoveryBioMed awarded NIH SBIR Phase 1 grant to discover and develop anti-inflammatory phytochemicals

DiscoveryBioMed, Inc. (DBM) today announced that it has been awarded a $200,000 Small Business Innovations Research (SBIR) Phase 1 grant by the National Institutes of Health (NIH) to continue research into the discovery and development of anti-inflammatory phytochemicals to address complications associated with nasal and pulmonary inflammation, dermatitis, and kidney disorders with an inflammatory component.

21 Apr 2010

Platelet rich plasma helps speed healing and bone formation following tooth removal

The use of platelet rich plasma (PRP) following tooth removal appears to speed healing and bone formation, according to an article in the Journal of Oral Implantology.

20 Apr 2010

Blood test to determine inflammation levels in body may help assess colon cancer risk: Study

A blood test used to determine the level of inflammation in the body may offer some help in assessing colon cancer risk, according to results of a study to be presented by Vanderbilt-Ingram Cancer Center's Gong Yang, M.D., MPH, at the 101st Annual Meeting of the American Association for Cancer Research.

20 Apr 2010

Wellstar International to install TMI Imaging system in Torrance, California

Wellstar International Inc. has announced they will be installing a system in Torrance, California.

20 Apr 2010

New book titled 'Advances in Wound Care' addresses major, escalating health problem

The publication of the new book Advances in Wound Care, addresses this major and escalating health problem. The first in an annual book series, Volume 1 strengthens the interdisciplinary continuum of wound care to synchronize the numerous disciplines the wound care community represents.

20 Apr 2010

First case of treating cystic fibrosis and Crohn's disease with infliximab

Cystic fibrosis (CF) is the most common life-threatening autosomal recessive disease in Caucasian children; it has an incidence of 1 case in every 2500 children born alive. CF involves an anomalous function of the exocrine glands, caused by a mutation of a gene (cystic fibrosis transmembrane conductance regulator, CFTR) located on chromosome 7, which codes for a protein involved in ion transport through the cell membrane.

20 Apr 2010

Even modest weight loss brings many health benefits

There have been repeated warnings related to the growing obese and diabetes related population in Australia. Studies have shown that nearly 50% Australians are either obese or overweight and thus suffer from its ill effects like heart disease, high cholesterol and type II diabetes.

20 Apr 2010

New research shows link between infection-related diseases and risk of cancer

New research is emerging that suggests a link between infection-related diseases and risk of cancer, according to findings presented here at the American Association for Cancer Research 101st Annual Meeting 2010.

20 Apr 2010

SPI-Bio to distribute and sell Aterovax's sPLA2 activity test in Europe

Aterovax SA, a company developing innovative products for atherosclerosis, today announced the signing of a 3 year, exclusive agreement with SPI-Bio, a specialist distributor of products and services in drug development, to distribute and sell Aterovax's sPLA2 activity test in Europe to academic and research laboratories for research use.

19 Apr 2010

Methotrexate therapy not recommended beyond 6 months after remission: JAMA

For patients with juvenile idiopathic arthritis in remission, withdrawal of treatment with the drug methotrexate over 12 months vs. 6 months did not reduce the rate of relapse, according to a study in the April 7 issue of JAMA.

19 Apr 2010

Study shows ultrathin flexible implants can effectively record brain activity

Scientists have developed a brain implant that essentially melts into place, snugly fitting to the brain's surface. The technology could pave the way for better devices to monitor and control seizures, and to transmit signals from the brain past damaged parts of the spinal cord.

19 Apr 2010

Study evaluates therapeutic effects of FXR and TGR5 agonist in PSC

Results of a study presented today at the International Liver Congress 2010 demonstrate that a dual FXR and TGR5 agonist decreases liver damage and modulates hepatic inflammation and fibrosis in a mouse model of primary sclerosing chlolangitis. In contrast, selective FXR or TGR5 agonists have no beneficial effect.

19 Apr 2010

Multinational phase II study: GS-9450 can reduce markers of liver damage in patients with NASH

Results from a multinational phase II study presented today at the International Liver CongressTM 2010 have shown that treatment with the caspase inhibitor GS-9450 can reduce markers of liver damage in patients with non-alcoholic steatohepatitis (NASH - the most serious form of non-alcoholic liver disease) as demonstrated by reduced levels of alanine and aspartate aminotransferases, hepatic enzymes that indicate cell damage.

17 Apr 2010

Inflammation News and Research

Nuon Therapeutics advances NU1618 into phase 2b development for chronic hyperuricemia in gout patients

Catabasis Pharmaceuticals to advance program targeting type 2 diabetes with $39.6 million Series A financing

Researchers detect link between alcohol consumption, cancer and aging

Merck to market and distribute MBL's Td vaccine in the U.S.

A*STAR's BMRC and SIgN award grants for twelve research projects on infectious diseases and immunology

Modest weight reduction reverses immune cell damage in obese people with diabetes

Gene test predicts statins' effectiveness in reducing risk of colorectal cancer

DiscoveryBioMed awarded NIH SBIR Phase 1 grant to discover and develop anti-inflammatory phytochemicals

Platelet rich plasma helps speed healing and bone formation following tooth removal

Blood test to determine inflammation levels in body may help assess colon cancer risk: Study

Wellstar International to install TMI Imaging system in Torrance, California

New book titled 'Advances in Wound Care' addresses major, escalating health problem

First case of treating cystic fibrosis and Crohn's disease with infliximab

Even modest weight loss brings many health benefits

New research shows link between infection-related diseases and risk of cancer

SPI-Bio to distribute and sell Aterovax's sPLA2 activity test in Europe

Methotrexate therapy not recommended beyond 6 months after remission: JAMA

Study shows ultrathin flexible implants can effectively record brain activity

Study evaluates therapeutic effects of FXR and TGR5 agonist in PSC

Multinational phase II study: GS-9450 can reduce markers of liver damage in patients with NASH

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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