Alveolar Macrophage News and Research

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Xuebijing injection reduces inflammation and ferroptosis in acute lung injury

Using an LPS-induced ALI mouse model and LPS-stimulated alveolar macrophages, they found XBJ reduced inflammatory cytokine surges, preserved alveolar barrier integrity, and limited tissue injury, while probing the molecular pathways and intracellular targets underlying these benefits.

7 Apr 2026

Neurons play a key role in reducing lung inflammation in pulmonary fibrosis

Researchers at the University of Calgary studying a lethal lung disease called pulmonary fibrosis have found neurons, which were known to help detect pain, are also critical for reducing harmful lung inflammation that leads to the disease.

16 Sep 2025

Lung cells in COPD patients show higher levels of soot-like carbon deposits

Cells taken from the lungs of people with chronic obstructive pulmonary disease (COPD) have a larger accumulation of soot-like carbon deposits compared to cells taken from people who smoke but do not have COPD, according to a study published today (Wednesday) in ERJ Open Research.

10 Jun 2025

Berry-flavored vapes impair lung immune response

Alterations in AM function following the exposure to berry-flavored e-cigarettes that lead to poor immune responses to pathogens and reduced host survival.

7 Nov 2024

New cell culture model sheds light on immune protein's role in infectious diseases

A human cell culture model of the lung's most important immune cells, alveolar macrophages, helped make a key finding that is prompting researchers to rethink the role of another immune protein in infectious disease.

10 Oct 2024

Unlocking the anti-inflammatory secrets of bergamot byproducts

The positive effect of bergamot derivatives.

17 Jan 2024

New cell culture model generates the alveolar macrophage in the lab

Researchers at Texas Biomedical Research Institute have succeeded in generating the lung's most important immune cell, the alveolar macrophage, in the lab.

12 Jun 2023

A novel role for macrophage-activation signaling in orchestrating the recruitment process in response to the SARS-CoV-2 spike protein

Researchers derived peptides from the SARS-CoV-2 spike protein to assess COVID-19-associated inflammatory changes using zebrafish models.

19 May 2023

Scientists explore efficacy of small molecule drugs against severe COVID-19 in vitro

Researchers evaluated the efficacy of small molecule drugs against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in vitro.

29 Dec 2022

How vaping impacts alveolar macrophage lipid content

The use of e-cigs increases the risk of acute respiratory syndrome.

11 Dec 2022

Two strains of TB bacterium attack the lungs in completely different fashion, study finds

Two strains of the bacterium causing tuberculosis have only minor genetic differences but attack the lungs in completely different fashion, according to Rutgers researchers.

18 Apr 2022

The latest advancements in polymer-based nanotechnology approaches used to fight against SARS-CoV-2

A recent review discusses the engineering versatility of polymeric nanoparticles - making a good therapeutic alternative against coronavirus diseases.

19 Jan 2022

Study suggests myeloid cell dysregulation is a driver of COVID-19 severity

Researchers determine the driving factors for disease severity and death due to COVID-19.

17 Jan 2022

Lysosomal-immune axis associated with COVID-19 severity

New research suggests the modulation of lysosomal-immune pathways may present a novel drug-targeting strategy to attenuate SARS-CoV-2 infections.

2 Feb 2021

Enzyme could play key role in treating cancer, autoimmune diseases in the airway

Findings from a research study, led by scientists at Henry Ford, published in the latest issue of Nature Communications suggest an enzyme could play an important role in the treatment of cancer and autoimmune diseases in the airway.

5 Aug 2020

Research shows basophils are key players in lung development

Lungs are vital organs required for the uptake of oxygen in exchange for carbon dioxide. However, the enormous complexity of the respiratory organ is often underestimated and deserves a closer look: A broad range of specialized cells work closely together to ensure the proper functioning of the lung and provide the vital gas exchange.

12 Oct 2018

Basophils play key role in development of macrophages in the lung

The adult lung consists of different, highly specialized cell types that are protected by a variety of immune cells.

12 Oct 2018

E-cigarettes not so safe but still better than cigarettes

According to latest research vaping using e-cigarettes can hasten the death of lung cells by up to fifty times and cause serious lung diseases later in life. This latest study was published in the journal Thorax.

14 Aug 2018

Lactic acid bacteria can offer protection against subtypes of influenza A virus

Lactic acid bacteria, commonly used as probiotics to improve digestive health, can offer protection against different subtypes of influenza A virus, resulting in reduced weight loss after virus infection and lower amounts of virus replication in the lungs, according to a study led by Georgia State University.

13 Dec 2017

Study: E-cigarettes appear to increase virulence of drug- resistant and life-threatening bacteria

Despite being touted by their manufacturers as a healthy alternative to cigarettes, e-cigarettes appear in a laboratory study to increase the virulence of drug- resistant and potentially life-threatening bacteria, while decreasing the ability of human cells to kill these bacteria

19 May 2014