Amyotrophic Lateral Sclerosis (ALS) News and Research

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Prolonged exposure to air pollution linked to elevated risk for ALS

Prolonged exposure to air pollution can be linked to an elevated risk for serious neurodegenerative diseases like ALS and seems to speed up the pathological process, report researchers from Karolinska Institutet in Sweden.

20 Jan 2026

Understanding the trends of various neurological disorders in the Chinese population

Neurological disorders represent a mounting public health crisis in China, exacerbated by rapid population aging.

19 Jan 2026

Axol Bioscience raises $2.8 M to advance US expansion and product development

Axol Bioscience Ltd. (Axol), a leading provider of induced pluripotent stem cell (iPSC) technologies for drug discovery and disease research, today announced that it has secured $2.8 million (£2.1 million) in funding.

13 Jan 2026

ALS breakthrough: Restoring protein production in motor neuron axons

Researchers at VIB and KU Leuven have identified a molecular process that allows motor neurons to maintain protein production, a process that fails in amyotrophic lateral sclerosis (ALS).

12 Jan 2026

SPINECRAFT: Engineering a 4D human spinal cord for disease research

Zaida Álvarez Pinto, Principal Investigator at the Institute for Bioengineering of Catalonia (IBEC), has been awarded an ERC Consolidator Grant, one of the most prestigious and competitive sources of funding in the European Union.

9 Jan 2026

Calcium signaling helps maintain protein quality in the endoplasmic reticulum

Calcium (Ca2+) drives many cellular functions, though the way it controls quality of proteins in the endoplasmic reticulum (ER), a cellular organelle that synthesizes and transports proteins, is widely unknown.

26 Dec 2025

Experimental drug targets early toxic amyloid to slow Alzheimer’s disease

An experimental drug developed at Northwestern University has demonstrated further promise as an early intervention for Alzheimer's disease.

18 Dec 2025

Scientists uncover why SETX-deficient cancer cells rely on error-prone DNA repair

The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break-when both sides of the DNA helix are cut at once.

4 Dec 2025

Protein tied to ALS and dementia plays a role in regulating DNA mismatch repair

New Houston Methodist research has revealed that a protein associated with neurodegenerative diseases such as dementia and amyotrophic lateral sclerosis (ALS) also plays a role in regulating DNA mismatch repair, a process essential for replicating genetic information and cell health.

2 Dec 2025

Global analysis shows rising burden of ALS and motor neuron diseases

Amyotrophic lateral sclerosis (ALS) and other motor neuron diseases (MNDs) are major global causes of death. However, their global incidence, mortality, and disability-adjusted life years remain largely unknown, despite their importance for disease prevention and resource allocation.

27 Nov 2025

Study reveals how TDP-43 causes neuronal overactivity in ALS and FTD

A new Northwestern University study using patient nervous tissue and lab-grown human neurons has uncovered how a key disease protein, TDP-43, drives overactive nerve cells in the neurodegenerative diseases amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).

31 Oct 2025

Enhancing ALS diagnosis with dual blood biomarkers

Despite modern imaging and genetic testing, diagnosing amyotrophic lateral sclerosis (ALS) remains challenging, particularly when distinguishing it from clinically similar neurodegenerative disorders.

29 Oct 2025

Exploring the gut-brain-immune axis in neurodegeneration

Neurodegenerative diseases (NDs), such as Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS), and multiple sclerosis (MS), represent a growing global health burden, particularly in aging populations.

28 Oct 2025

Blood test shows promise for faster ALS diagnosis

New research by UCLA Health has found a simple blood test could provide faster and more accurate diagnosis of ALS by measuring cell-free DNA.

15 Oct 2025

ALS and MS share striking geographic patterns, research shows

A new study published in Nature's Scientific Reports indicates that amyotrophic lateral sclerosis (ALS) and multiple sclerosis (MS) have an extremely high geographic association, even after controlling for race, gender, wealth, latitude, and access to neurological healthcare.

15 Oct 2025