Angiotensin Converting Enzyme 2 News and Research

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Kenyan bat coronavirus uses human CEACAM6 to enter cells, raising spillover concerns

Researchers screened a phylogenetically diverse panel of alphacoronavirus spike proteins and found that a heart-nosed bat coronavirus from Kenya can use human CEACAM6 to enter cells.

23 Apr 2026

SARS-CoV-2 rarely reaches first-trimester placentas but still disrupts early pregnancy immunity

Researchers analyzing 761 first-trimester pregnancies found that SARS-CoV-2 was rarely detected in placental tissues, suggesting in utero transmission early in pregnancy is uncommon. However, maternal infection was linked to immune dysregulation at the maternal-fetal interface, altered trophoblast signaling, and inflammatory changes that could affect placental development.

14 Apr 2026

Trial evaluates a traditional Chinese herbal formula for diabetic kidney disease with macroalbuminuria

Diabetic kidney disease affects a growing proportion of people with diabetes and remains the leading cause of end-stage renal disease.

30 Dec 2025

ARB drugs lead to better blood pressure treatment adherence

Patients who start their blood pressure treatment with ARB drugs continue with the same medicine to a greater extent than patients who start out with other drugs.

22 Dec 2025

Single-pill combination medications may simplify treatment for adults with high blood pressure

Taking one pill that combines two or more blood pressure medications may help adults with high blood pressure (also known as hypertension) lower their blood pressure level faster and more effectively than taking multiple medications separately, and it may also reduce the risk of heart attack and stroke, according to a new scientific statement published today in the American Heart Association's journal Hypertension.

15 Dec 2025

Lubiprostone shows signs of slowing kidney function decline in chronic kidney disease

In adults with stage IIIb–IV chronic kidney disease, the constipation drug lubiprostone did not reduce gut-derived uremic toxins but preserved creatinine-based kidney function over 24 weeks. The benefit was linked to microbiome remodeling, increased polyamine production, and improved mitochondrial function rather than toxin lowering.

8 Dec 2025

Complete revascularization reduces the risk of death from cardiovascular causes

Opening all blocked arteries with stents in patients with a heart attack, known as complete revascularization, reduces the risk of death from cardiovascular causes, death from any cause and future heart attacks compared with opening only culprit artery causing the heart attack according to a new, large international study led by researchers at the Population Health Research Institute (PHRI), a joint organization of McMaster University and Hamilton Health Sciences.

10 Nov 2025

Drinking orange juice daily may fine-tune genes tied to cardiovascular wellness

Regular orange juice consumption reprograms immune-cell gene activity linked to blood pressure, lipid metabolism, and inflammation in healthy adults. The molecular effects differ by body weight, suggesting BMI-tailored benefits from this everyday beverage.

9 Nov 2025

Azelastine nasal spray prevents COVID-19 and rhinovirus infections

Researchers discuss the effects of azelastine nasal spray on the rate of SARS-CoV-2 infection as compared to placebo.

6 Oct 2025

Can nut-based milks match dairy for safety, nutrition and flavor?

Tree nut-based beverages offer healthy fats but lack protein. Innovations in fortification and fermentation could enhance their nutritional value.

3 Oct 2025

How gluten harms some people but helps others

New insights reveal gluten's health potential, highlighting beneficial peptides and innovative methods to enhance wheat safety for sensitive individuals.

3 Oct 2025

New class of antihypertensive medications may have both kidney- and cardio-protective benefits

Adding the novel medication baxdrostat to standard care may help manage high blood pressure and delay the progression of kidney disease in people with chronic kidney disease and uncontrolled high blood pressure , according to preliminary research presented at the American Heart Association's Hypertension Scientific Sessions 2025.

8 Sep 2025

Sacubitril/valsartan shows benefit over enalapril in heart failure caused by Chagas disease

In patients with heart failure (HF) caused by Chagas disease, sacubitril/valsartan was superior to enalapril for the composite primary endpoint, predominantly driven by a significant reduction in N-terminal pro-B-type natriuretic peptide (NT-proBNP), according to late-breaking research presented in a Hot Line session today at ESC Congress 2025.

3 Sep 2025

Study links COVID-19 infection to accelerated blood vessel aging in women

A Covid infection, particularly in women, may lead to blood vessels aging around five years, according to research published in the European Heart Journal on 18th August, 2025.

18 Aug 2025

New 2025 guidelines focus on early intervention and lifestyle to manage high blood pressure

Preventing and managing high blood pressure with healthy lifestyle behaviors, such as following a heart-healthy diet including reducing salt intake, staying physically active, maintaining a healthy weight and managing stress—combined with early treatment with medication to lower blood pressure if necessary—are recommended to reduce the risk of heart attack, stroke, heart failure, kidney disease, cognitive decline and dementia, according to a new clinical guideline published today in the American Heart Association's peer-reviewed journals Circulation and Hypertension, and in JACC, the flagship journal of the American College of Cardiology.

14 Aug 2025

Cedars-Sinai study finds new way to combat Alzheimer’s in preclinical models

In a preclinical study, Cedars-Sinai investigators found that boosting angiotensin converting enzyme (ACE) in key immune cells called microglia in the brain helped protect the brains of specially bred laboratory mice against Alzheimer's disease.

6 Aug 2025

New strategy reveals how mannose receptor helps regulate blood proteins

The amount of each of the more than a thousand different glycoproteins in your blood varies widely with the 10 most abundant glycoproteins accounting for 90 percent of the total mass.

30 Jul 2025

Date vinegar lowers blood sugar and cholesterol in type 2 diabetes

This study reveals that red date vinegar intake improves blood glucose and lipid profiles in type 2 diabetes, indicating potential for metabolic risk reduction.

22 Jul 2025

Smartwatch alerts retired nurse to heart injury, prompting life-saving hospital care

A smartwatch detected abnormal ECG changes in a 76-year-old woman experiencing chest pain following emotional stress. Hospital investigations confirmed takotsubo (stress) cardiomyopathy, highlighting the potential and limitations of wearable health technology in acute cardiac care.

10 Jun 2025

Integrating phytomedicine and nanotechnology in managing COVID-19 related heart disease

Acute coronary syndrome (ACS) in patients with SARS-CoV-2 infection represents a critical intersection of viral-induced inflammation and cardiovascular pathology.

22 May 2025