Asparagine News and Research

RSS

Restricting select amino acids may mimic protein restriction’s healthy aging benefits

A review finds that restricting protein, particularly methionine, isoleucine, and valine, may improve metabolism and influence key aging pathways, largely in experimental models. Short human studies suggest metabolic benefits, but effects on lifespan remain unknown and restriction may harm people with unmet or increased protein needs.

3 Aug 2026

Nine gut bacteria linked to future type 2 diabetes risk

Research identifies specific gut microbes associated with future type 2 diabetes risk, emphasizing the impact of dietary fiber on microbiome health.

9 Jul 2026

Gut microbes may reveal who is at risk of type 2 diabetes years before diagnosis

A large Swedish prospective cohort study found that specific gut microbial species and metabolic pathways measured years before diagnosis were associated with future type 2 diabetes risk. The findings suggest that gut microbiome composition and functional potential may help explain T2D development, but replication is needed before clinical use.

28 May 2026

Gut microbiome may be a central player in the body's response to cancer

A new study reveals how bacteria in the gut can help determine whether the amino acid asparagine from the diet will feed tumor growth or activate immune cells against the cancer, according to researchers at Weill Cornell Medicine.

29 Jan 2026

AI model ranks genetic variants from severe to mild disease mutations

popEVE combines evolutionary insights with human population data to identify damaging genetic mutations, improving variant scoring for rare diseases.

3 Dec 2025

Mediterranean diet lowers dementia risk by altering key metabolites

Researchers linked genetics, plasma metabolites, and Mediterranean diet adherence to dementia risk in two large US cohorts, showing APOE4 homozygotes had distinct metabolic pathways. Diet-related metabolites mediated protection, highlighting precision-prevention opportunities.

26 Aug 2025

Flavonols found in foods can block drug resistance protein and boost medication absorption

Researchers identified specific flavonols that potently inhibit breast cancer resistance protein (BCRP), a key driver of drug resistance and poor oral drug absorption. The study found that these flavonols can reverse chemotherapy resistance in vitro and boost drug exposure in animal models, though clinical translation remains uncertain.

6 Aug 2025

Amino acid metabolism in breast cancer as a driver of disease and therapeutic target

The review introduces the molecular subtypes of breast cancer and outlines how altered amino acid metabolism supports tumor growth.

7 Jul 2025

UIC scientists redesign asparaginase to minimize leukemia treatment side effects

University of Illinois Chicago scientists have redesigned a treatment for the most common pediatric leukemia to eliminate its severe side effects, like blood clots and liver damage.

31 Jan 2025

New research sheds light on how monkeys avoid hepatitis B infection

Hepatitis B virus (HBV) infection is a leading cause of chronic liver diseases, that spreads among individuals through blood or body fluids.

4 Dec 2024

Lipidomics and metabolomics as potential biomarkers for breast cancer progression

This review highlights the potential of lipidomic and metabolomic biomarkers in predicting breast cancer prognosis and therapy response, enhancing patient care.

5 Sep 2024

Brazilian researchers identify possible biomarkers associated with recurrence of vivax malaria

The most common type of malaria in Brazil is caused by the parasite Plasmodium vivax. Although vivax malaria is milder than the variant caused by P. falciparum, the ability of P. vivax to produce dormant forms in the host's liver that can be reactivated months after the end of treatment makes it very hard to control.

24 Jun 2024

Metabolomics study finds biomarkers predicting autism in newborns

A study in Communications Biology utilized metabolomics in newborns to identify markers that might predict autism spectrum disorder (ASD), finding distinct metabolic profiles in children with ASD compared to typically developing children.

14 May 2024

Hearing loss linked to accelerated Alzheimer's progression via GDF1 pathway

Study unveils the GDF1 signaling pathway's role in mitigating the adverse effects of hearing loss on Alzheimer's disease, spotlighting potential avenues for therapeutic development.

20 Mar 2024

Healthy lifestyles linked to specific metabolic markers, large study finds

Researchers identify metabolomic markers linked to healthy lifestyles in a large study, showing a connection between lipid metabolism and reduced mortality risks.

18 Feb 2024

New study reveals flaws in AI tools used for SARS-CoV-2 antibody discovery

A discovery program for SARS-CoV-2-nABs potentially targeting its resistant strains.

19 Jan 2024

Hidden identity of blood cancer revealed

Leukemia is a common term used to refer to a form of blood cancer. However, there are different types of leukemia depending on the cell type involved.

9 Jan 2024

Discovery of a novel therapeutic target for pancreatic cancer

A novel amino acid transporter-based therapeutic target for pancreatic ductal adenocarcinoma (PDAC).

10 Oct 2023

Unlocking the power of lectins: BOA emerges as a potent weapon against all SARS-CoV-2 variants

Researchers discover that antiviral lectins like BOA can effectively inhibit SARS-CoV-2 and its variants by targeting spike glycans, opening doors for potential pan-coronavirus treatments. The study reveals that BOA's multivalent interactions make it a potent inhibitor against a range of viral variants, offering promise for future therapeutic strategies.

14 Sep 2023

Clovibactin - a game-changing novel antibiotic with no resistance

Researchers reported the discovery of a new antibiotic, clovibactin.

6 Sep 2023