Atorvastatin News and Research

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Atorvastatin reduces major cardiovascular events but misses disability-free survival goal

Atorvastatin reduced major cardiovascular events by 30% in older people without known cardiovascular disease, diabetes or dementia, but did not significantly improve disability-free survival, according to results presented in a Hot Line session today at ESC Congress 2026 and published simultaneously in the New England Journal of Medicine.

29 Aug 2026

Some statins may increase erectile dysfunction risk

Research indicates that certain statins, particularly atorvastatin and simvastatin, may elevate the risk of erectile dysfunction, impacting men's health.

6 Jul 2026

Statins may trigger muscle side effects by activating inflammatory danger signals

An experimental study in Science Advances shows that statins, primarily fluvastatin in these experiments, may promote low-level muscle myopathy by reducing isoprenoid-dependent protein prenylation rather than by cholesterol lowering. In primed muscle cells and mouse models, impaired YAP signaling, reduced glycolysis, NLRP3/caspase-1 activation, and nuclear FOXO accumulation increased atrogin-1, reduced protein synthesis, and weakened muscle function.

22 Jun 2026

Intravenous statins during heart attack reduce cardiac muscle damage

Reducing the damage sustained by the heart during a myocardial infarction remains one of the major challenges in cardiology, even when the blocked coronary artery is reopened in a timely manner.

11 Jun 2026

Autism risk rises with multiple medications taken during pregnancy

A study links maternal use of cholesterol-inhibiting medications during pregnancy to increased autism risk in children, urging caution in prescribing practices.

22 Apr 2026

Certain prenatal medications linked to increased risk of autism

A landmark study led by researchers at the University of Nebraska Medical Center (UNMC) and published in Molecular Psychiatry has identified a significant association between prenatal prescription of commonly utilized medications and the risk of autism spectrum disorder (ASD) in children.

20 Apr 2026

Most statin side effects are not backed by trials

Research indicates that many statin therapy side effects are not supported by evidence, suggesting a need for revised labeling to improve treatment decisions.

9 Feb 2026

UBC researchers reveal how statins trigger muscle damage

Statins have transformed heart health, saving millions of lives by lowering cholesterol and reducing the risk of heart attacks and strokes.

26 Nov 2025

Advances in diagnosis and management of chronic subdural hematoma

Chronic subdural hematoma (CSDH) is one of the most common neurosurgical conditions, particularly among the elderly, with an annual incidence ranging from 1.7 to 20.6 per 100,000 people.

18 Nov 2025

REBOOT trial finds no benefit of beta blockers after uncomplicated heart attacks

Beta blockers-drugs commonly prescribed for a range of cardiac conditions, including heart attacks-provide no clinical benefit for patients who have had an uncomplicated myocardial infarction with preserved heart function.

30 Aug 2025

How do common painkillers drive stronger E. coli resistance?

Research shows that non-antibiotic medications like ibuprofen can enhance E. coli mutations, raising concerns about antimicrobial resistance in older adults.

29 Aug 2025

Common painkillers ibuprofen and paracetamol found to fuel antibiotic resistance

Ibuprofen and paracetamol are common over-the-counter medications that many of us reach for when we're sick. But new research from the University of South Australia shows that these trusted staples are quietly fuelling one of the world's biggest health threats: antibiotic resistance.

25 Aug 2025

This test can see a heart attack in your future

A long list of Lynda Hollander's paternal relatives had heart disease, and several had undergone major surgeries. So when she hit her mid-50s and saw her cholesterol levels creeping up after menopause, she said, "I didn't want to take a chance."

1 Aug 2025

FAU experts recommend high-potency statins to reduce LDL cholesterol

There is broad consensus that the overall body of evidence shows lowering LDL (low-density lipoprotein) cholesterol provides both statistically significant and clinically meaningful benefits in treating and preventing cardiovascular disease.

31 Jul 2025

Cardiologists urged to prioritize potent statins in managing LDL cholesterol

28 Jul 2025

Plant-based fitness supplements for reversing metabolic syndrome

Research indicates that specific plant-based supplements, combined with exercise, can improve cardiometabolic markers in those at risk for metabolic syndrome.

2 Jul 2025

New study supports non-surgical approach for select cases of acute subdural hematoma

Acute subdural hematoma (ASDH) is a common brain lesion resulting from traumatic brain injuries and is associated with high mortality and morbidity.

27 Jun 2025

Australia faces critical medicine shortages amid global supply challenges

About 400 medicines are in short supply in Australia. Of these, about 30 are categorized as critical. These are ones with a life-threatening or serious impact on patients, and with no readily available substitutes.

12 May 2025

Grapefruit juice and its effects on prescription drugs

Grapefruit juice can interfere with how certain medications work by affecting drug metabolism and absorption, leading to either increased side effects or reduced effectiveness. The FDA requires warnings on some drugs due to these interactions, making it essential to check labels and consult healthcare providers.

28 Feb 2025

U.S. wastewater treatment fails to address rising organofluorine contamination

Municipal wastewater treatment plants remove less than 25% of extractable organofluorine, with fluorinated pharmaceuticals dominating contaminants and posing significant risks to U.S. drinking water quality.

7 Jan 2025