Biochemistry News and Research

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Study uncovers new shortcut mechanism behind cancer cell division

Living cells are one of the few materials that can replicate themselves, and this is crucial for tissue development and recovering from injury or illness.

6 Nov 2026

Vulnerable DNA sites make cancer cells sensitive to PARP inhibitors

A small subset of vulnerable DNA sites can make cancer cells highly sensitive to targeted drugs called PARP inhibitors, a new study shows.

5 Nov 2026

Nanoparticle structural design improves disease biomarker detection sensitivity

A nanoparticle's performance depends on more than what it is made of-it can also depend on how its building blocks are arranged.

3 Nov 2026

New study identifies biological mechanism driving therapy resistance in advanced prostate cancer

A multi-institutional collaborative study led by researchers at the University of Chicago and the Fred Hutchinson Cancer Center has identified a previously unknown biological mechanism that controls cell identity and treatment resistance in advanced prostate cancer.

3 Nov 2026

Key innate immune protein regulates cholesterol and influences cancer treatment resistance

Scientists at the University of North Carolina Lineberger Comprehensive Cancer Center have discovered an unexpected role for a key innate immune protein, revealing how it helps regulate cholesterol levels inside cells and influences tumor growth and treatment response.

3 Nov 2026

New strategy exploits a hidden genetic vulnerability in multiple cancers

Researchers have found a surprisingly common vulnerability in a broad variety of cancers and have begun designing drug compounds to exploit it, in a study led by investigators at Weill Cornell Medicine.

2 Nov 2026

Light-activated molecular cages offer precise control over protein degradation

Researchers have created a molecular "cage" that keeps protein-degrading drug molecules inactive until they are exposed to low-energy red light.

30 Oct 2026

Targeting specific enzyme reverses radiation-induced immune suppression in cancer

Researchers at the University of Chicago identified a mechanism to make immune cells reprogrammed by radiation therapy attack tumors rather than protect them.

30 Oct 2026

Newly discovered protein helps preserve egg chromosome integrity during aging

Eggs follow a very different developmental path from sperm. Once a male hits puberty, sperm cells are produced continuously throughout his life.

29 Oct 2026

University of Utah researchers discover backup energy system in the heart

The heart is the hardest-working muscle in the body, beating constantly no matter what the body's energy reserves look like.

28 Oct 2026

New model reduces trial and error in mass spectrometry imaging

Andrei Fedorov and his team have found a way to take some of the guesswork out of mass spectrometry imaging (MSI), potentially giving scientists better tools to explore the molecules that influence our health.

27 Oct 2026

Smart probe makes aggressive breast cancer cells glow during surgery

Surgical removal of a tumor remains the primary defense against most solid cancers. However, for surgeons in the operating room, differentiating between the outer edges of a tumor and healthy tissue is a challenge.

26 Oct 2026

Researchers discover how faulty matrix structure leads to cell death in newly formed bone

Bone cells called osteocytes help maintain skeletal strength, but how newly formed osteocytes survive remains unclear.

26 Oct 2026

Newly discovered protein controls the space between mitochondrial membranes

Mitochondria are the tiny powerpacks that supply most of the energy our cells need. Their ability to generate this energy relies on a distinctive architecture: two membranes, one tucked inside the other, separated by a narrow gap called the intermembrane space (IMS).

23 Oct 2026

Researchers call for microbiome moonshot to tackle chronic diseases

Rutgers researchers are part of an international call for a microbiome moonshot, a massive, coordinated effort to pinpoint how certain microorganisms inside us drive chronic disease and how others can be harnessed for repair.

23 Oct 2026

Penn State study identifies new regulator of jumping genes

As much as half of the human genome is composed of so-called "jumping genes." These DNA sequences can make copies of themselves that are inserted back into the genome at another location, playing a significant functional role in creating the diversity that drives evolution and in regulating how other genes are turned on or off.

21 Oct 2026

New study identifies protein factor linked to chronic liver disease

The mechanisms that cause the world's most common chronic liver disease — Metabolic dysfunction-associated steatotic liver disease (MASLD) — to develop and progress are not still fully understood.

20 Oct 2026

Light-activated experimental opioid eliminates dangerous side effects

Opioid painkillers are some of the strongest analgesic medicines, but they are also the riskiest owing to a range of side effects, including addiction.

15 Oct 2026

New immune profiling tool identifies antibodies that trigger preterm births

A typical pregnancy lasts 40 weeks, but for about 1 in 10 pregnant women labor begins too soon. Premature or preterm birth is the leading cause of newborn deaths worldwide.

14 Oct 2026

Buck Institute and Georgetown lead effort mapping harmful protein changes before disease begins

A research "super team" co-led by theBuck Institute for Research on Aging and Georgetown University has received an award of up to $51.7 million from the Advanced Research Projects Agency for Health (ARPA-H) to predict how disease-causing proteins misfold before irreversible damage occurs and use those predictions to develop novel diagnostics and treatments.

12 Oct 2026