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UCLA advances CRISPR gene-editing therapy for sickle cell disease

A UCLA-led team has described how they advanced an experimental CRISPR approach for sickle cell disease into a blood stem cell therapy that can be manufactured at the scale and quality required for a clinical trial.

4 Nov 2026

UK doctors transplant frozen testicular tissue to restore fertility

Doctors in Edinburgh have performed a pioneering procedure to transplant a young man's testicular tissue that was frozen before he underwent chemotherapy, in a potential breakthrough for male fertility preservation.

8 Oct 2026

UK first as frozen testicular tissue transplanted to help restore fertility

7 Oct 2026

Clinicians' words hold power to heal or harm patients

Dr. Wendy Harpham was 36 years old and a successful physician who prided herself on her empathy. Then she was diagnosed with cancer.

21 Sep 2026

New mRNA vaccine expands flu protection options for older adults

Every fall, millions of Americans heed the call to get their annual flu shot. Getting vaccinated reduces the risk of severe illness, hospitalization, and death from influenza.

20 Sep 2026

New prime assembly method enables long and precise DNA insertions

Genomic editing holds great potential yet continues to have its limitations. Most current methods either rely on untargeted gene delivery or short DNA edits that need to be individualized to each patient.

16 Sep 2026

New brain atlas reveals insights into Huntington's, addiction, and other disorders

A region of the brain called the striatum is critical for many cognitive and motor functions, including decision-making, control of movement, habit formation, and processing of reward.

1 Sep 2026

Senolytic drugs rejuvenate blood stem cells in sickle cell disease

Sickle cell disease causes premature aging of blood stem cells, which scientists may be able to address with a special class of drugs, according to a new study from St. Jude Children's Research Hospital.

22 Jul 2026

Stem cell transplantation is the most cost-effective sickle cell treatment

Stem cell transplantation is the most cost-effective option for long-term care of sickle cell disease in adults when compared with gene therapy and standard of care treatment, according to new research published in Blood.

2 Jun 2026

New genomic study tracks rare blood disease in children

Aplastic anemia is a rare, life-threatening blood disorder where patients are unable to make enough blood cells due to the immune system's attack on blood stem cells. The condition can progress to myelodysplastic syndrome (MDS) and leukemia. A study led by scientists at St. Jude Children's Research Hospital, with multiple collaborating institutions, used state-of-the-art genomic techniques to profile 619 children and adults with aplastic anemia.

4 May 2026

Sickle cell disease care is unevenly distributed across regions in New York State

Sickle cell disease (SCD) is the most common inherited blood disorder in the United States. Approximately 10 percent of people with SCD in the US live in New York State, with the majority residing in New York City.

4 May 2026

Intercellular heme transfer pathway sustains red blood cell production under stress

Scientists have long been puzzled by how maturing red blood cells manage to produce all the hemoglobin they need to carry oxygen to tissues, even after shedding the vital structures they need to produce it.

25 Apr 2026

Gene-edited treatment shows promising outcomes for severe sickle cell disease

New results from a clinical trial show promising outcomes for a gene-edited treatment for severe sickle cell disease, a genetic blood disorder with few curative options.

1 Apr 2026

Study reveals high burnout among doctors treating sickle cell disease

Hematology-oncology trained physicians who treat sickle cell disease reported higher rates of burnout (60%) than their counterparts who do not provide sickle cell care (43%) despite no differences in grit and resilience between the two groups.

12 Mar 2026

Disrupted iron levels after SARS-CoV-2 infection may trigger long COVID

Problems with iron levels in the blood and the body's ability to regulate this important nutrient as a result of SARS-CoV-2 infection could be a key trigger for long COVID, new research has discovered.

6 Mar 2026

Breakthrough gene therapy for sickle cell disease remains out of reach in Africa

As Uganda rolls out mandatory nationwide screening of newborns for sickle cell disease this month, a gene therapy celebrated in the United States and Europe remains financially out of reach for most patients in Africa.

25 Feb 2026

Fondazione Telethon achieves milestone with Waskyra approval for Wiskott-Aldrich Syndrome

Fondazione Telethon announces the positive opinion issued by the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) recommending marketing authorization in the European Union for Waskyra, an ex vivo gene therapy for Wiskott-Aldrich Syndrome (WAS), a rare and life-threatening primary immunodeficiency.

14 Nov 2025

Blood Disorder News and Research

UCLA advances CRISPR gene-editing therapy for sickle cell disease

UK doctors transplant frozen testicular tissue to restore fertility

UK first as frozen testicular tissue transplanted to help restore fertility

Clinicians' words hold power to heal or harm patients

New mRNA vaccine expands flu protection options for older adults

New prime assembly method enables long and precise DNA insertions

New brain atlas reveals insights into Huntington's, addiction, and other disorders

Senolytic drugs rejuvenate blood stem cells in sickle cell disease

Stem cell transplantation is the most cost-effective sickle cell treatment

New genomic study tracks rare blood disease in children

Sickle cell disease care is unevenly distributed across regions in New York State

Intercellular heme transfer pathway sustains red blood cell production under stress

Gene-edited treatment shows promising outcomes for severe sickle cell disease

Study reveals high burnout among doctors treating sickle cell disease

Disrupted iron levels after SARS-CoV-2 infection may trigger long COVID

Breakthrough gene therapy for sickle cell disease remains out of reach in Africa

Fondazione Telethon achieves milestone with Waskyra approval for Wiskott-Aldrich Syndrome

Using placental growth factor to predict preeclampsia risk in pregnant women with sickle cell disease

Gut microbial imbalance linked to chronic sickle cell disease pain

Timely opioid treatment lowers hospitalizations in children with sickle cell disease

Industry Focus eBook - Cell biology (5th edition) eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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