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New review shows why antidepressants often fail in Alzheimer’s and Parkinson’s depression

A Molecular Psychiatry review shows that depression in Alzheimer’s and Parkinson’s disease may reflect disease-specific molecular, neurotransmitter, inflammatory, and circuit-level disruptions rather than standard depression biology alone. It argues that broad antidepressants often show limited efficacy in these patients and that future trials should use biomarkers, neuroimaging, and symptom profiling to guide targeted treatments.

7 Jul 2026

Updated ABCs framework gives clinicians a clearer path to prevent heart disease

A 2026 State-of-the-Art review updates the ABCs of cardiovascular disease prevention to help clinicians apply contemporary risk assessment, lifestyle, pharmacologic, and cardiometabolic strategies in routine care. The framework emphasizes PREVENT™ risk equations, Life’s Essential 8, CKM syndrome, obesity care, lipid lowering, blood pressure control, healthy aging, heart failure prevention, and atrial fibrillation management.

7 Jul 2026

Psychiatry may be moving closer to precision medicine

For decades, treating depression has largely involved a difficult form of medical guesswork: prescribing one antidepressant after another in hopes that one will eventually help.

6 Jul 2026

Study links semaglutide and tirzepatide to fewer anxiety and depression diagnoses in obesity care

A US electronic health record study found that adults with obesity who started semaglutide or tirzepatide had lower recorded hazards of anxiety and depression than matched patients using naltrexone-bupropion. However, among adults without type 2 diabetes, tirzepatide was linked to higher recorded hazards of anxiety and insomnia than semaglutide, underscoring the need for cautious monitoring.

1 Jul 2026

New review questions whether vaping consistently helps smokers quit

A new review paper in Nicotine and Tobacco Research, published by Oxford University Press, finds that while research has previously found that vaping is associated with subsequently quitting smoking, that may not always be true.

30 Apr 2026

Certain prenatal medications linked to increased risk of autism

A landmark study led by researchers at the University of Nebraska Medical Center (UNMC) and published in Molecular Psychiatry has identified a significant association between prenatal prescription of commonly utilized medications and the risk of autism spectrum disorder (ASD) in children.

20 Apr 2026

Vaping beats traditional tools for quitting smoking

The review indicates nicotine e-cigarettes could surpass traditional quit aids in effectiveness, but lingering safety uncertainties warrant further research.

31 Mar 2026

Patients who stop GLP-1 drugs often restart or try alternatives

The study highlights that after stopping GLP-1 medications, many patients resume treatment or try alternatives, influencing weight management strategies.

17 Mar 2026

Smoking cessation apps can boost quit rates, especially alongside medication

Smartphone apps show promise in smoking cessation, outperforming minimal support and enhancing traditional interventions, according to a recent meta-analysis.

16 Jan 2026

Prescription drug advertising proves more effective in reducing smoking rates

A new peer-reviewed study in the INFORMS journal Marketing Science finds that direct-to-consumer (DTC) advertising for prescription smoking-cessation drugs meaningfully reduces cigarette use. At the same time, the research found that advertising for over the counter (OTC) nicotine products does not reduce cigarette use.

22 Oct 2025

Common painkiller and antidepressant combo may increase seizure risk in older adults

When older adults living in nursing homes are prescribed the pain medicine tramadol alongside certain antidepressants, their risk of seizures may go up, according to a study published October 8, 2025, in Neurology, the medical journal of the American Academy of Neurology.

8 Oct 2025

Why women’s periods once synced with the moon — and what changed

Study reveals women's menstrual cycles follow lunar gravity, with synchronization detected during strong seasonal alignments despite artificial light effects.

30 Sep 2025

New guideline offers effective options to help Canadians quit smoking

Tobacco smoking is the number one cause of preventable disease and death in Canada; it is highly addictive and hard to stop.

25 Aug 2025

Brain’s energy control map offers blueprint for next-gen weight loss therapies

Scientists map how the brain integrates hormonal and neural signals from the body to control appetite, energy use, and reward pathways, revealing targets for next-generation anti-obesity drugs. This review highlights the interplay between neuroendocrine circuits, neuroplasticity, and pharmacotherapy for durable, non-aversive weight loss.

11 Aug 2025