Calcitriol News and Research

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Calcitriol is a form of Vitamin D3 with three alcohol groups. It increases gastrointestinal calcium absorption, stimulates osteoclastic calcium resorption from bone, facilitates the effect parathyroid hormone (PTH) has on bone resorption, and increases renal tubular absorption of calcium. Production of calcitriol by the cells of the proximal tubule of the nephron in the kidney is stimulated by hypocalcemia and hypophosphatemia as well as parathyroid hormone.

Could vitamin D in midlife protect your brain from early Alzheimer’s?

Higher serum vitamin D in midlife is associated with reduced tau burden in the brain, highlighting its potential role in early dementia risk assessment.

7 Apr 2026

Genetic variants influencing vitamin D synthesis, metabolism, and transport

A Canadian review synthesizes genetic factors that influence vitamin D synthesis, metabolism, and transport, highlighting how polymorphisms affect circulating levels. It also explores how gene-environment interactions shape individual responses to supplementation and sunlight.

20 Aug 2025

Nanoparticles could slow rheumatoid arthritis progression and reduce flare severity

As a chronic condition, rheumatoid arthritis (RA) can't be cured, so treatment focuses on managing the disease and controlling its progression. Although current treatments help control RA symptoms in most people, they cannot prevent the onset of RA or painful flare-ups.

6 Aug 2025

Study identifies SDR42E1's role in vitamin D pathway

Vitamin D is not only an essential nutrient, but also the precursor of the hormone calcitriol, indispensable for health: it regulates the uptake of phosphate and calcium necessary for bones by the intestines, as well as cell growth and the proper function of muscles, nerve cells, and the immune system.

18 Jul 2025

Vitamin D curbs colorectal cancer by boosting immunity and blocking tumor growth

Review highlights how vitamin D, particularly its active form calcitriol, modulates immune responses, inflammation, and tumor progression to help prevent colorectal cancer (CRC). Evidence suggests adequate vitamin D levels and supplementation reduce CRC risk and improve outcomes.

21 Apr 2025

Can yogurt and kefir help prevent osteoporosis? Scientists examine the facts

Fermented dairy products and probiotics may support bone health by enhancing calcium absorption, modulating inflammation, and influencing bone remodeling, though human studies show mixed results.

18 Mar 2025

Vitamin D receptor activation slows cell overgrowth in pulmonary hypertension

The study demonstrates that activating the vitamin D receptor (VDR) with calcitriol suppresses cell proliferation in pulmonary arterial smooth muscle cells, potentially reducing disease severity in pulmonary arterial hypertension (PAH).

12 Nov 2024

Vitamin D deficiency persists despite easy access, review suggests need for tailored supplements

Researchers in a study published in the journal Nutrients delve into the pervasive issue of vitamin D deficiency and its link to various health conditions, advocating for precision nutrition and personalized supplementation to enhance vitamin D intake and effectiveness.

17 Apr 2024

Vitamin D shows promise in targeting aging's biological mechanisms, study finds

What is currently known about the potential effect of vitamin D (VitD) on modulating some hallmarks of aging.

26 Mar 2024

Vitamin D receptor presence in breast cancer tumors linked to better survival outcomes

Research identifies vitamin D receptors (VDR) in breast cancer tumors as a promising prognostic marker, linking VDR presence to tumor characteristics, survival outcomes, and potentially informing treatment strategies.

25 Mar 2024

Does vitamin D have protective role against COVID-19?

Whether vitamin D supplementation before the onset of COVID-19 could provide benefits.

1 Mar 2024

Proper serum levels of vitamin D may have a protective effect against breast cancer

The impact of vitamin D on breast cancer (BC).

22 Feb 2024

$Study suggests Vitamin D prescription lowers hip fracture incidence$

Calcitriol News and Research

Could vitamin D in midlife protect your brain from early Alzheimer’s?

Genetic variants influencing vitamin D synthesis, metabolism, and transport

Nanoparticles could slow rheumatoid arthritis progression and reduce flare severity

Study identifies SDR42E1's role in vitamin D pathway

Vitamin D curbs colorectal cancer by boosting immunity and blocking tumor growth

Can yogurt and kefir help prevent osteoporosis? Scientists examine the facts

Vitamin D receptor activation slows cell overgrowth in pulmonary hypertension

Vitamin D deficiency persists despite easy access, review suggests need for tailored supplements

Vitamin D shows promise in targeting aging's biological mechanisms, study finds

Vitamin D receptor presence in breast cancer tumors linked to better survival outcomes

Does vitamin D have protective role against COVID-19?

Proper serum levels of vitamin D may have a protective effect against breast cancer

Study suggests Vitamin D prescription lowers hip fracture incidence

Link found between vitamin D deficiency and metabolic abnormalities in children: New insights unveiled

The immunomodulatory and antiviral function of vitamin D

Vitamin D supplementation reduces risk of major cardiovascular events in older adults

Does vitamin D play an anti-viral role against SARS-CoV-2?

Experts provide first framework for treating hypercalcemia of malignancy in adults

Activated vitamin D3 inhibits arsenic-mediated carcinogenesis in certain skin cells, research shows

Does vitamin D reduce COVID-19 severity?

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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