Cartilage News and Research

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Cartilage is a stiff yet flexible connective tissue found in many areas in the bodies of humans and other animals, including the joints between bones, the rib cage, the ear, the nose, the elbow, the knee, the ankle, the bronchial tubes and the intervertebral discs.

Inflammatory macrophages identified as drivers of chronic joint osteoarthritis

Researchers have identified a group of inflammatory macrophages that drive osteoarthritis by sustaining inflammation in the synovium – a layer of connective tissue within joints – and show that they can target these immune cells to treat the disease in mice.

28 Oct 2026

Hēlo system offers minimally invasive solution for chronic venous thromboembolism

Patients with persistent blood clots require frequent medical interventions just to survive. Yet despite this critical need, there have been few advancements in how these patients are treated.

27 Oct 2026

Investigational knee injection targets cartilage loss in osteoarthritis patients

Keck Medicine of USC has launched a clinical trial testing the safety and tolerability of a new investigational treatment and its potential effects on preventing cartilage deterioration in people with knee osteoarthritis, the most common form of the disease.

14 Oct 2026

New AI tool distinguishes Ewing sarcoma with high accuracy

A team from the Universitat Politècnica de València (UPV) and the University of Valencia (UV) has developed and validated an artificial intelligence (AI) system capable of distinguishing Ewing sarcoma from other morphologically similar tumours with high accuracy.

13 Oct 2026

Study identifies Piezo channels as targets for orthodontic care

A new review in Genes & Diseases highlights Piezo channels as important biological links between mechanical forces and the cellular processes that shape the face, move teeth and influence oral health.

12 Oct 2026

Exercise therapy reduces knee osteoarthritis risk after ACL surgery

Exercise-based rehabilitation and education can reduce the chance of knee osteoarthritis following ACL reconstruction in people aged under 40, as well as improve pain and quality of life, a study by La Trobe University researchers has found.

29 Sep 2026

Low-dose radiation shows lasting benefits in patients with knee osteoarthritis

Low-dose radiation therapy may do more than relieve pain from early knee osteoarthritis, with a long-term analysis suggesting it could also influence how the disease progresses.

27 Sep 2026

Early treatment significantly reduces joint damage in rheumatoid arthritis

Early and consistently managed treatment can have a decisive impact on the course of rheumatoid arthritis and prevent permanent joint damage.

11 Sep 2026

Two collagen receptors cooperate to enhance cranial bone regeneration

Bone repair depends on skeletal progenitor cells (SPCs) moving to injured areas and developing into bone-forming cells, but how these cells respond to their surroundings remains unclear.

8 Sep 2026

Prednisone may impair bone health in children with Duchenne muscular dystrophy

In a new study published in Scientific Reports, an international and multidisciplinary research team including Binghamton University researchers identified a set of blood proteins that may explain why the corticosteroid prednisone, although beneficial in treating Duchenne muscular dystrophy (DMD), can interfere with childhood growth and bone health.

4 Sep 2026

Tissue-mimicking scaffold may enable more durable rotator cuff repairs

Researchers have developed a "scaffold" that mimics natural tissue and could lead to more durable rotator cuff repairs, including for large injuries and cases involving bone and tissue degeneration that are often the most difficult to fix.

25 Aug 2026

$Muscle cells play a vital role in repairing fractured bones$

Muscle cells play a vital role in repairing fractured bones

Bone healing is a complex process that depends on the coordinated activity of many different cell types.

14 Aug 2026

New review explores purinergic signaling pathways in osteoarthritis progression

A growing understanding of purinergic signaling is reshaping how scientists view osteoarthritis (OA), revealing an intricate communication network that influences joint inflammation, cartilage degeneration, bone remodeling, and chronic pain.

7 Aug 2026

Combining genetics and AI to discover new osteoarthritis drugs

Osteoarthritis (OA) is a chronic, painful joint disease and a leading cause of disability. Despite its prevalence, therapies for osteoarthritis are limited and focus on symptom management.

6 Aug 2026

Nerve-blocking therapy improves growth plate repair in injured bones

With the support of National Institutes of Health funding, Johns Hopkins Medicine investigators, led by pathologist Aaron W. James, M.D., Ph.D., previously discovered that sensory neurons in skeletal tissue are constantly sensing their environment and are quick to respond to injuries.

5 Aug 2026

Blocking the Axl receptor may offer a new way to promote bone formation

Osteoporosis is one of the most common age-related bone diseases, affecting millions of people worldwide and increasing the risk of fractures, disability, and reduced quality of life.

28 Jul 2026

Study links collagen peptides to improved bone health in runners

Collagen is a protein found in skin, hair, nails, tendons, cartilage, and bones. Our bodies naturally produce collagen using the foods we eat. But, in recent years, collagen peptides have gained popularity as a supplement to support joint, hair, skin, and gut health.

22 Jul 2026

Oral microbiome imbalances may contribute to symptomatic hand arthritis

Specific imbalances and disruptions to the oral microbiome have been linked to symptomatic hand arthritis by a study published online in the open access journal RMD Open.

22 Jul 2026

UCD professor wins ERC grant for pediatric growth disorder research

Professor Niamh Nowlan of University College Dublin (UCD) has been awarded a European Research Council (ERC) Proof of Concept Grant for research with the potential to enable new treatments for a broad range of paediatric growth disorders.

30 Jun 2026

Immune cells drive abnormal joint tissue growth in rheumatoid arthritis

Researchers at Hospital for Special Surgery (HSS) have identified a specialized population of immune cells that play a central role in driving abnormal tissue growth in rheumatoid arthritis (RA), offering new insight into disease progression and potential treatment strategies.

24 Jun 2026