Disease Modeling News and Research

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Space-grown organoids better replicate aggressive glioblastoma tumors

Glioblastoma (GBM) is the most common malignant primary brain tumor in adults and is one of the most aggressive and deadly forms of cancer.

30 Oct 2026

Researchers develop versatile genetic tool to investigate cell interactions

Our bodies are composed of many different types of cells that work together to build and maintain normal physiological functions.

27 Oct 2026

C-Path and University of Arizona collaborate to investigate cellular mechanisms of Parkinson's disease in women

Critical Path Institute (C-Path) today announced a research collaboration with the University of Arizona to investigate the cellular mechanisms that drive Parkinson's disease in women.

6 Oct 2026

MIT researchers build cell collection device for early cancer detection

One of the main reasons that ovarian cancer is among the deadliest forms of cancer is timing: When doctors catch it early, the five-year survival rate can be north of 90 percent.

24 Sep 2026

Mount Sinai researchers discover how Alzheimer's gene damages blood vessels

Mount Sinai researchers have identified how APOE4, the strongest genetic risk factor for Alzheimer's disease, damages the brain's blood vessels and promotes the buildup of abnormal proteins linked to neurodegenerative disease.

24 Sep 2026

Scientists develop lab-grown heart tissue model for heart failure

Scientists study the underlying causes of a disease or test new potential drugs in animal models or cells obtained from human biopsy specimens before clinical trials.

2 Sep 2026

New dashboard tracks flesh-eating screwworm threat across the United States

In the 1950s, the New World screwworm cost U.S. livestock producers tens of millions of dollars a year, as much as $50 to $100 million annually in the hardest-hit Southwest, before it was eradicated from the United States and pushed south to Panama.

11 Aug 2026

PRDM16 regulates the balance between proliferation and maturation in human cardiomyocytes

Understanding how heart muscle cells stop dividing and acquire the characteristics needed to sustain lifelong cardiac function remains one of the greatest challenges in cardiovascular biology.

7 Aug 2026

New review advances understanding of biological mechanisms driving Ménière's disease

A comprehensive new review is bringing together the latest advances in Ménière's disease, offering a clearer picture of the biological mechanisms that may drive this complex inner ear disorder while highlighting new directions for diagnosis, disease modeling, and treatment.

6 Aug 2026

New website tracks vaccine preventable diseases across the United States

A new website will track the spread of vaccine-preventable diseases across the United States to offer the public, the media, healthcare providers, public health officials, and policymakers reliable and visual information about current disease trends.

5 Aug 2026

Stem cell study uncovers molecular pathway for enamel regeneration

Tooth enamel is the hardest substance in the human body, yet once damaged, it cannot regenerate naturally.

9 Jul 2026

New accessible multiplex imaging workflow advances spatial liver research

Spatial biology technologies are reshaping modern biomedical research by enabling the visualization of cellular organization and interactions within intact tissues.

26 Jun 2026

Asymptomatic transmission plays a prominent role in mpox infection patterns

A Kaiser Permanente study of nearly 8,000 men shows that in mid- to late 2024, mpox was far more common among men who have sex with men than previously thought. Individuals without symptoms accounted for most infections and likely played a prominent role in transmission, contrary to prior assumptions that people had to be symptomatic to spread the disease.

15 May 2026

Advanced 3D heart models could transform cardiovascular drug discovery

Cardiovascular disease remains a leading global health burden, yet many preclinical systems still struggle to predict how candidate drugs will perform in the human heart.

10 May 2026

The power of organoids in speeding up lifesaving drug development

Organoids are miniature tissue or organ models formed by stem cells (including pluripotent stem cells, tissue-specific adult stem cells, etc.) or progenitor cells in an in vitro three-dimensional culture system, which possess structural features and partial functions analogous to their corresponding in vivo organs. In 2009, the Hans Clevers laboratory developed the first intestinal organoid, marking the inception of organoid-based disease modeling.

8 May 2026

Atelerix launches STORganoid cryo-free preservation solution for complex 3D cell models

Atelerix, a biotech company revolutionizing cell preservation and biological transport with its pioneering hydrogel encapsulation technology, today announced the launch of STORganoid™, an ambient-temperature preservation solution for organoids and spheroids.

From Atelerix Ltd 21 Apr 2026

Stem cell study identifies universal checkpoint controlling cell identity

A study published in Cell Research advances a central idea in stem cell biology by identifying a checkpoint that controls the identity of many different types of stem cells across developmental stages.

8 Apr 2026

Researchers track how youth drinking deaths changed worldwide over 31 years

A global analysis of GBD 2021 data found that youth drinking contributed to 417,198 deaths across 194 WHO member countries and territories between 1990 and 2021, with deaths declining from 13,346 to 10,563 over the period. Boys and young men bore a far higher burden, and most alcohol-attributable deaths were linked to transport injuries, interpersonal violence, and self-harm, with marked disparities across SDI levels and countries.

6 Apr 2026

ATP delivery fixes dysfunctional dopamine packaging in Parkinson's neurons

A new study shows how dysfunctional packaging of the neurotransmitter dopamine triggers toxic processes in neurons - and how this can be repaired with simple delivery of energy (ATP).

2 Mar 2026

Engineers develop highly precise gene editor for safer cystic fibrosis treatments

Engineers at the University of Pennsylvania and Rice University have refined a technology for editing individual genetic "base pairs" to a new level of precision, opening the door to safer, more reliable therapies for a wide range of genetic diseases, and to potential treatments for some cystic fibrosis patients that may yield better outcomes than existing therapies.

23 Feb 2026