Drug Resistant Tuberculosis News and Research

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Scientists identify new drug target to combat airborne tuberculosis

Tuberculosis bacteria released into the air from infected individuals dry out to form infectious particles that are second only to measles in contagiousness.

26 Aug 2026

Can ibuprofen improve drug-resistant tuberculosis treatment?

While ibuprofen reduced inflammatory markers in drug-resistant TB patients, it did not enhance treatment outcomes, indicating the need for further research.

3 Jul 2026

Single-dose malaria treatment using four drugs achieves high cure rates in clinical trial

Hundreds of malaria patients participating in a Phase 3 clinical trial in Gabon in West Africa were cured via a single dose of a treatment that utilizes four widely available malaria drugs, according to a new study presented today at the Annual Meeting of the American Society of Tropical Medicine and Hygiene (ASTMH).

12 Nov 2025

endTB-Q trial highlights importance of individualized regimens

Some patients with highly drug-resistant tuberculosis could benefit from a shorter treatment with fewer drugs while others may warrant more aggressive therapy, according to the findings of a new study led by an international group of researchers including scientists from Harvard Medical School and conducted across six countries in Asia, Africa, and South America.

17 Jul 2025

Tuberculosis cases continue to rise in Europe

New data published by ECDC and the World Health Organization (WHO) Regional Office for Europe show that with almost 39,000 reported tuberculosis cases in 2023, the 29 European Union and European Economic Area (EU/ EEA) countries continue to see increases in TB notifications.

24 Mar 2025

Three new drug regimens offer hope for drug-resistant tuberculosis

Tuberculosis remains one of the top infectious disease killers worldwide, a challenge amplified by drug-resistant forms of the disease.

29 Jan 2025

Groundbreaking trial finds levofloxacin effective against multidrug-resistant TB

A clinical trial published in the New England Journal of Medicine showed that the oral antibiotic levofloxacin taken once-daily for six months substantially reduced the risk of developing drug-resistant tuberculosis (TB), and almost halved adults' and children's risk of developing multidrug-resistant TB.

15 Jan 2025

Quabodepistat combo shows promise for safer, faster tuberculosis treatment

Study highlights the safety and early bactericidal activity of quabodepistat when combined with delamanid, bedaquiline, or both, offering potential for shorter and more tolerable tuberculosis treatment regimens.

1 Dec 2024

Study finds weakness in drug-resistant tuberculosis pathogens

A University of Otago-led study has found highly vulnerable weakness in drug-resistant Mycobacterium tuberculosis, offering a new way to kill them.

13 Nov 2024

Rutgers study sheds light on how bedaquiline fights drug-resistant tuberculosis

Rutgers Health research has uncovered why a relatively new antibiotic for tuberculosis (TB) works against multidrug-resistant strains, potentially inspiring improved treatments and drug development strategies.

13 Nov 2024

WHO reports alarming rise in tuberculosis cases in 2023

The World Health Organization (WHO) today published a new report on tuberculosis revealing that approximately 8.2 million people were newly diagnosed with TB in 2023 – the highest number recorded since WHO began global TB monitoring in 1995.

29 Oct 2024

Novel semi-synthetic compound shows promise against drug-resistant tuberculosis

A new study published in the American Society for Microbiology journal Microbiology Spectrum demonstrates that a novel semi-synthetic compound can be derived from natural compounds to produce potent activity against Mycobacterium tuberculosis, including multi-drug resistant strains.

3 Oct 2024

Study reveals gaps in outbreak detection resources in Asia

A landmark study led by Duke-NUS Medical School revealed that despite the recent pandemic, outbreak detection efforts remain under-resourced in South and Southeast Asia, with only about half the countries reviewed having integrated pathogen genomic surveillance initiatives in their national plans.

24 Sep 2024

Harnessing immune enhancement to combat drug-resistant tuberculosis

Experts are working on novel immune-enhancing therapies called host-directed therapies to use the body's own immune system to target tuberculosis, with hopes that they could tackle even the drug-resistant forms of the disease.

26 Apr 2024

Second-line treatment for drug-resistant tuberculosis is as effective as first-line medicines

Patients who have drug-resistant tuberculosis (TB) have a similar microbiological response to bedaquiline-based second-line medications as patients with drug-sensitive TB taking first-line regimens, according to researchers at Weill Cornell Medicine in New York and GHESKIO Centers in Haiti.

27 Feb 2024

Welch Foundation grant supports UTA research on drug-resistant tuberculosis

With a $300,000 grant, the Welch Foundation is supporting University of Texas at Arlington research into why some types of Mycobacterium tuberculosis (Mtb), the bacteria that causes the lung disease tuberculosis (TB), do not respond to treatments.

2 Feb 2024

Uniting Against Antimicrobial Resistance: An Interview with the World Health Organization

An interview with Kitty van Weezenbeek, Director of Surveillance, Prevention and Control of AMR for the World Health Organistion (WHO) AMR division.

20 Nov 2023

Researchers develop new way to boost immune cells' ability to fight TB

Tuberculosis is old - ancient even. The infectious bacterial disease that plagued Old Testament Israelites and took down pharaohs was eventually stunted by vaccinations, antibiotics, and public health measures like isolation, but it hasn't been cured yet.

27 Sep 2023