Dyslipidemia News and Research

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Dyslipidemia is a disruption in the amount of lipids in the blood.

Coffee, tea and dementia risk: Why the amount you drink could matter

A targeted perspective synthesizes epidemiological and mechanistic evidence examining how caffeine consumption during midlife may influence dementia risk later in life. The authors highlight potential roles for dose, age, CYP1A2 genotype, adenosine signaling and cultural drinking practices, while stressing that current observational evidence cannot establish causality.

3 Sep 2026

Too little or too much testosterone may matter for heart rhythm

A review of clinical trials, observational studies, genetic analyses, and mechanistic research suggests that atrial fibrillation risk may follow a U-shaped relationship with testosterone, increasing at both low and high levels. Evidence on testosterone replacement therapy remains mixed, with researchers calling for prospective studies to determine whether mid-physiological testosterone targets and treatment formulation influence AF risk.

2 Sep 2026

The scale told a similar story across three diets. The liver told a different one

In a randomized controlled trial of people with metabolically unhealthy obesity, approximately 10% weight loss improved insulin sensitivity and several cardiometabolic measures across ketogenic, Mediterranean, and very-low-fat plant-forward diets. However, the very-low-carbohydrate ketogenic diet produced larger improvements in hepatic insulin sensitivity and greater reductions in liver fat and several glucose and insulin measures than the higher-carbohydrate diets.

31 Aug 2026

Experts call for safer weight loss as concerns grow over GLP-1 use

An editorial in Diabetology International argues that inappropriate GLP-1 use should be judged not only by regulatory compliance or off-label prescribing, but also by whether weight reduction is medically safe, nutritionally adequate, and properly supervised. Drawing on Japanese reports of ketosis and ketoacidosis following inappropriate tirzepatide use, the authors call for greater attention to the risks of unsafe weight-loss practices alongside medication-related harms.

30 Aug 2026

Blood-brain barrier-crossing blood pressure drugs linked to lower dementia risk

In a large Australian cohort of adults with hypertension, use of blood-brain barrier-crossing antihypertensive medications was associated with a lower risk of dementia and mortality than use of non-crossing drugs. The association was strongest for beta-blockers and angiotensin II receptor blockers, although the observational design means the findings cannot establish causality.

27 Aug 2026

Japan vaccinated heavily during COVID-19. Why are so many unsure about vaccinating next time?

A nationwide Japanese survey found that only 53.1% of respondents said they would accept vaccination in a hypothetical future pandemic with COVID-19-like fatality, despite substantially higher previous COVID-19 vaccine uptake. Willingness varied by demographics, perceived disease risk, exposure to misinformation, vaccine characteristics, and practical factors such as cost, evidence, professional recommendations, and accessibility.

24 Aug 2026

Could a daily vinegar drink help with constipation? A small trial offers a clue

A randomized, double-blind trial found that adults with mild constipation who drank a vinegar beverage daily for four weeks had more frequent bowel movements than those receiving placebo. Exploratory findings also suggested earlier improvements in bowel habits, although the small feasibility-based trial requires confirmation in larger and more diverse populations.

24 Aug 2026

What happens to body fat when people follow the Eatwell Guide?

Higher adherence to the UK Eatwell Guide was associated with lower BMI, waist circumference, total body fat, and trunk fat in more than 156,000 UK Biobank participants. The associations persisted prospectively across demographic, physical activity, and genetic-risk groups, supporting the role of diet quality in weight management.

16 Aug 2026

Insilico Medicine nominates powerful oral drug candidate for the management of heart risks

Insilico Medicine, a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, today announced the nomination of ISM0900, a potent, AI-driven, highly selective, orally available small molecule inhibitor of lipoprotein(a), or Lp(a), as a preclinical candidate (PCC) for the management of cardiovascular risks.

12 Aug 2026

Type 2 diabetes linked to more severe menopause symptoms

The type of menopause symptoms, as well as their severity, can differ greatly among women. A number of earlier studies have suggested various reasons for those differences.

5 Aug 2026

Exercise helps protect Hispanic adults from late life cognitive decline

Previous studies have examined the associations between adherence to LS7 and cognitive outcomes, with findings suggesting that higher LS7 scores are associated with better cognitive performance, reduced dementia risk and improved brain health.

4 Aug 2026

New study reveals massive gap in American blood pressure care

Nearly 23 million Americans with blood pressure 130/80 mm Hg or higher may be eligible for blood-pressure-lowering medications based on the 2025 American Heart Association/American College of Cardiology guideline, according to new, independent research published today in the Journal of the American Heart Association, an open access, peer-reviewed scientific journal of the American Heart Association.

29 Jul 2026

Stuffed toys can release short-chain PFAS into saliva, study finds

Researchers tested 18 stuffed toys and found that all released at least one targeted PFAS into artificial saliva under mouthing-relevant conditions, with PFHxA driving much of the variation between products. Modeled intake of the four PFAS covered by EFSA’s group tolerable weekly intake remained below that benchmark, but some high-PFHxA toys had reduced margins of exposure, and water rinsing produced mixed results.

22 Jul 2026

Childhood ultra-processed food intake associates with altered insulin responses

Researchers analyzed dietary and metabolic data from 508 nondiabetic Mexican American children in the SAFARI family cohort, finding that higher ultra-processed food scores were associated with lower insulin sensitivity and altered early insulin secretion measures. The exploratory cross-sectional study did not establish causality, and its multiple comparisons, historical dietary data, and questionnaire-based UPF estimates warrant confirmation in longitudinal studies and trials.

21 Jul 2026

New machine learning model improves cholesterol calculation accessibility

The Martin-Hopkins equation to assess low-density lipoprotein (LDL) cholesterol levels in blood samples has been used by laboratories in the U.S. and other countries to guide efforts to lower cardiovascular disease risk.

15 Jul 2026

Study: Bariatric surgery is safe, effective for obese adolescents and young adults

A new study from researchers at LSU's Pennington Biomedical Research Center, FMOL Health | Our Lady of the Lake Regional Medical Center and Metamor Institute demonstrates that metabolic and bariatric surgery can be delivered safely and effectively for adolescents and young adults living with severe obesity, offering promising improvements in weight loss and obesity-related health conditions.

13 Jul 2026