An Electronic Health Record (EHR) is a longitudinal electronic record of patient health information generated by one or more encounters in any care delivery setting. Included in this information are patient demographics, progress notes, problems, medications, vital signs, past medical history, immunizations, laboratory data, and radiology reports. The EHR automates and streamlines the clinician's workflow. The EHR has the ability to generate a complete record of a clinical patient encounter, as well as supporting other care-related activities directly or indirectly via interface—including evidence-based decision support, quality management, and outcomes reporting.
In a natural experiment involving 72,920 propensity-matched US adults aged 60 years and older, recombinant shingles vaccination was associated with a 9% lower cardiovascular disease burden over seven years compared with the live attenuated vaccine. Lower burdens of ischemic heart disease and heart failure were seen in both sexes, while ischemic stroke was significantly lower only among men, supporting further clinical trials and mechanistic studies
A large retrospective cohort study found that GLP-1 receptor agonist use was associated with a lower risk of tuberculosis in people with type 2 diabetes compared with sulfonylureas, metformin, DPP-4 inhibitors, and SGLT2 inhibitors. The observational findings suggest a possible benefit beyond metabolic control, but the authors emphasize that prospective and mechanistic studies are needed to determine whether GLP-1 therapies themselves reduce TB risk.
America's health care system is under pressure with demand rising, hospital capacity strained and the number of patients who need care the most increasing faster than the system was built to serve.
An AI foundation model extracted hidden physiological patterns from routine polysomnography and identified five patient groups with distinct long-term risks of mortality, cardiovascular disease, and neurological disorders. The approach outperformed apnea–hypopnea index severity categories for risk stratification and remained informative in an independent sleep cohort.
A study of nearly 100,000 adults treated for suspected infection suggests that the National Early Warning Score (NEWS2), a score based on routinely collected vital signs that is widely used to identify patients at risk of clinical deterioration, may help clinicians identify which patients are most likely to benefit from immediate antibiotic treatment and which may safely undergo further evaluation before receiving antibiotics.
Vanderbilt Health researchers have received a grant from Eli Lilly and Company, a multinational pharmaceutical company headquartered in Indianapolis, to build an artificial intelligence (AI) tool within the electronic health record system (EHR) to get patients with Alzheimer's disease to treatment faster.
NYU Langone Health and Dana-Farber Cancer Institute have formed a strategic collaboration to co-develop Solavia Decision Suite, a next-generation oncology support platform designed to improve cancer care for patients and clinicians alike.
Researchers from RWJBarnabas Health and Rutgers Robert Wood Johnson Medical School found that an artificial intelligence (AI)-enabled early warning system helped identify hospitalized patients at risk of rapid clinical decline sooner, contributing to fewer deaths among high-risk patients.
Researchers developed Oncoformer, a multimodal transformer that analyzes longitudinal health records and chest X-rays to classify cancer, predict diagnoses up to one year in advance, infer tumor stage, and forecast treatment response and recurrence risk. Validation across large independent cohorts showed strong performance, although prospective trials in diverse, average-risk populations are needed before clinical use.
Newer GLP-1 receptor agonists, including semaglutide and tirzepatide, were associated with fewer alcohol-related ED visits or hospitalizations among adults with alcohol use disorder and type 2 diabetes or obesity.
Pediatricians who participated in the collaborative mental health program at Ann & Robert H. Lurie Children's Hospital of Chicago were more likely to diagnose and treat anxiety and depression in kids without reliance on additional support from specialists, according to a study published in Academic Pediatrics.
Obesity can act as fuel for leukemia, according to a study led by Indiana University School of Medicine scientists.
New research from The University of Texas at Arlington suggests that introducing electronic health record training earlier in nurse practitioner programs could help address a significant challenge facing the field-burnout among experienced clinicians who supervise and train future nurse practitioners.
The study shows semaglutide's cardiovascular benefits are more closely tied to attained dose than weight loss, challenging existing treatment assumptions.
Current GLP-1 receptor agonist prescriptions were associated with modestly lower AUDIT-C scores in a large, diverse US cohort. The difference appeared to reflect less frequent drinking rather than fewer drinks per occasion or fewer binge-drinking episodes.
The 2025-2026 COVID-19 vaccines were associated with 50% estimated effectiveness against COVID-19-associated emergency department and urgent care encounters among immunocompetent US adults. They were also linked to an estimated 55% effectiveness against COVID-19-associated hospitalization, providing added protection beyond existing immunity from prior infection or vaccination.
This study is the first to analyse obesity trends from 2019 to 2025, using NHS England electronic health records covering nearly 55 million adults.
Researchers analyzed more than 910,000 adults and found that SARS-CoV-2 infection was associated with a higher adjusted risk of new-onset obstructive sleep apnea up to 4.5 years later. The association appeared in both hospitalized and non-hospitalized COVID-19 patients, supporting targeted screening in higher-risk post-COVID groups while highlighting the need for objective sleep testing.
At least 12 percent of Americans now communicate with their healthcare providers about appointments, test results, and ongoing treatments via secure online patient portals and health apps, a new study shows.
MIRA, an autonomous AI agent tested in a sandboxed electronic health record, diagnosed 574 real emergency department cases with 88.9% accuracy and outperformed physicians in a matched 311-case comparison. The system ordered tests, generated medication plans, and made admission decisions in simulation, but the authors stress that prospective validation, governance, and physician oversight are still essential.
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