Gabapentin News and Research

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Gabapentin (brand name Neurontin) is a medication originally developed for the treatment of epilepsy. Presently, gabapentin is widely used to relieve pain, especially neuropathic pain.

Researchers identify opioids with highest risk of respiratory depression

University of Manchester researchers have identified which opioids are most likely to be associated with respiratory depression, in a major new study.

9 Jul 2026

New national program targeting harmful and unnecessary medicine use in Australia

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1 Jul 2026

Non-hormonal menopausal medication improves mood and hot flashes

The first real-world study of the FDA-approved non-hormone treatment fezolinetant found the menopausal medication improved hot flashes, depression and anxiety in women, according to industry-sponsored research being presented Sunday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill.

14 Jun 2026

Psilocybin may provide long-lasting relief from chronic nerve pain

A single dose of psilocybin - the active compound in magic mushrooms - reduces nerve pain for up to a month and makes a widely used painkiller work more effectively, University of Reading research has found.

22 May 2026

UCL study urges clinician vigilance when prescribing gabapentinoids for pain

People who take gabapentinoids, a medication prescribed increasingly frequently worldwide, particularly for chronic pain, face a much greater risk of drug poisoning if they are also taking another medication, finds a new study by University College London (UCL) researchers.

17 Apr 2026

Common nerve pain drugs may set off prescribing cascades in older patients

Clinicians may fail to recognize common side effects of drugs like gabapentin - which are frequently prescribed for nerve pain - leading them to prescribe unnecessary medications that cause yet more side effects.

2 Dec 2025

Why are more older people dying after falls?

For a while, walking the dog felt hazardous. Earl Vickers was accustomed to taking Molly, his shepherd-boxer-something-else mix, for strolls on the beach or around his neighborhood in Seaside, California. A few years ago, though, he started to experience problems staying upright.

15 Sep 2025

Survey shows ongoing misconceptions about hormone therapy safety in cancer survivors

Despite evidence suggesting the safety of hormone therapy for patients with a history of low-grade endometrial or epithelial ovarian cancer, a new survey shows that many gynecologists and some gynecologic oncologists are still uncomfortable prescribing the therapy for this patient population.

10 Sep 2025

Pregabalin raises heart failure risk in older adults compared to gabapentin, study finds

A large Medicare cohort study found that older adults prescribed pregabalin had a significantly higher risk of developing heart failure compared to those prescribed gabapentin. The elevated risk was most pronounced in individuals with pre-existing cardiovascular disease, especially women and White patients.

13 Aug 2025

Study finds continued use of risky antiseizure drugs during pregnancy

Despite evidence of the risk of malformations at birth, or birth defects, use of some antiseizure drugs during pregnancy has persisted, according to a study published on July 23, 2025, in Neurology, the medical journal of the American Academy of Neurology.

24 Jul 2025

Taking specific antiseizure drugs during pregnancy linked to increased risk of malformations at birth

A new study that examined older and newer medications to treat seizures has found that using some medications during pregnancy is linked to an increased risk of malformations at birth, or birth defects.

16 Jul 2025

Frequent gabapentin use linked to higher dementia and cognitive impairment risk

Receiving six or more prescriptions of the drug gabapentin for low back pain is associated with significantly increased risks of developing dementia and mild cognitive impairment (MCI)--29% and 85%, respectively-finds a large medical records study published online in the journal Regional Anesthesia & Pain Medicine.

10 Jul 2025

Experimental drug could offer pain relief without the side effects of opioids

An experimental drug developed at Duke University School of Medicine could offer powerful pain relief without the dangerous side effects of opioids.

19 May 2025

Cellular bridges aid axon growth after spinal cord damage

Capitalizing on the flexibility of tiny cells inside the body's smallest blood vessels may be a powerful spinal cord repair strategy, new research suggests.

21 Apr 2025

Antiseizure medications in pregnancy tied to child neurodevelopment risks

Researchers investigate how anti-seizure medication use during pregnancy may increase the risk of neuropsychological conditions in children.

20 Nov 2024

New insights into pain signaling could lead to better chronic pain treatment

When pain signals are passed along the nervous system, proteins called calcium channels play a key role. Researchers at Linköping University, Sweden, have now pinpointed the exact location of a specific calcium channel fine-tuning the strength of pain signals.

18 Nov 2024

Study reveals racial bias in postsurgical analgesia

While recovering from major surgery, Black patients may be less likely to receive certain multimodal analgesia options and more likely to receive oral opioids than white patients, according to research being presented at the ANESTHESIOLOGY® 2024 annual meeting.

21 Oct 2024

Long-term low-dose antiviral treatment reduces eye disease risk from shingles

Long-term, low-dose antiviral treatment reduces the risk for potentially vision-damaging bouts of inflammation and infection, as well as pain, which occur when shingles affects the eye, according to new research presented October 19 at the annual meeting of the American Academy of Ophthalmology (AAO) in Chicago.

20 Oct 2024

New insights into stiff-person syndrome, advancing diagnosis and treatment

Research explores the complexities of diagnosing and treating stiff-person syndrome, emphasizing the uncertain role of GAD antibodies and the promise of novel therapies.

5 Sep 2024

Genetic marker predicts gabapentin response in chronic pelvic pain

Women who carry a particular form of a pain gene are more likely to respond well to a common medication used to treat long-term discomfort, research shows.

15 Jul 2024