Gliomas News and Research

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Inhibitory neurons act as a brake on brain tumor growth

Brain tumors do not grow in isolation. They develop within the highly active environment of the brain, where neurons continuously exchange electrical and chemical signals.

7 Sep 2026

Study reveals why diffuse midline glioma develops in brain midline regions

Scientists at St. Jude Children's Research Hospital have shown that specific brain cells respond differently to the H3.3 K27M, a mutation in the histone H3.3 protein that drives many cases of diffuse midline glioma (DMG), depending on the cell's location in the developing brain.

27 Aug 2026

New ultrasound technique breaches blood brain barrier to treat gliomas

In a promising sign for the potential of focused sound waves to improve care for brain tumors, UVA Health researchers have determined that tumors called gliomas may be even more receptive to targeted drug delivery than normal brain tissue.

30 Jul 2026

Multimodal surgery improves outcomes for rare corpus callosum glioma

Brain tumor surgeries are particularly challenging due to the difficult trade-off neurosurgeons often face—remove more tumor and risk neurological injury, or preserve function and leave more tumor behind.

17 Jul 2026

New study explains how brain tumors evolve to resist treatment

A form of glioma, a type of brain cancer, tends to progress towards greater malignancy due to an increasing tendency of the glioma cells to transform into immature, stem-cell-like states, according to a study led by investigators at Weill Cornell Medicine, the New York Genome Center, Harvard Medical School and Mass General Brigham.

11 Jul 2026

Study potential new therapeutic strategy for patients with ATRX-mutant gliomas

A new study from researchers at The University of Texas MD Anderson Cancer Center has uncovered how one of the most common genetic alterations in glioma rewires the cancer cell genome to fuel tumor progression, suggesting a potential new therapeutic strategy for patients with ATRX-mutant gliomas.

1 Jul 2026

Low-methionine diet shows promise against aggressive brain tumors

An unexpected lab observation led a team of scientists to discover how diet can influence survival in animal models of glioma, one of the most aggressive and deadly forms of brain cancer.

10 Jun 2026

Cytokine-armored CAR-T cell therapy successfully attacks aggressive brain tumors in mice

Scientists at the UCLA Health Jonsson Comprehensive Cancer Center have developed a new cytokine-armored CAR-T cell therapy that helps the immune system better attack aggressive brain tumors in mice while reducing dangerous side effects that have long limited immune-based treatments for glioblastoma, one of the deadliest and most treatment-resistant brain cancers.

20 May 2026

New 3D organoid model advances pediatric glioma research and treatment

A three-dimensional experimental system has been developed to study the response to drugs in low-grade glioma, a tumor of the central nervous system that often occurs in children.

9 Apr 2026

Scientists win awards for the discovery of genomic imprinting and tumor’s power grid

For their discovery of genomic imprinting, developmental biologists Davor Solter and Azim Surani will receive the 2026 Paul Ehrlich and Ludwig Darmstaedter Prize, endowed with €120,000, on March 14 at Frankfurt’s Paulskirche.

13 Mar 2026

Boron neutron capture therapy shows promise for deadly brain tumors

Malignant gliomas are among the deadliest brain cancers, with limited treatment options and poor survival.

9 Mar 2026

Phase 2 clinical trial tests LMP744 for the treatment of first-time recurrent glioblastoma

Gibson Oncology, a clinical-stage private pharmaceutical company headquartered in Miami, announced it has entered Phase 2 clinical trials with LMP744 for the treatment of first-time recurrent glioblastoma patients.

25 Feb 2026

Time of radiotherapy influences cancer treatment response

A team of researchers from the Andalusian Centre for Molecular Biology and Regenerative Medicine (CABIMER) and the University of Seville, in collaboration with the Virgen Macarena University Hospital, have identified a fundamental mechanism that links the 24-hour circadian cycle to the precise repair of DNA breaks.

13 Feb 2026

Researchers uncover mechanisms of three mismatch repair deficient high-grade glioma subtypes

Researchers have uncovered the mechanisms behind three unique subtypes of mismatch repair deficient high-grade gliomas.

10 Feb 2026

Time of radiotherapy can influence the effectiveness of cancer treatment

30 Jan 2026

Digital twin technology guides personalized treatment for brain cancer patients

A new machine-learning-based approach to mapping real-time tumor metabolism in brain cancer patients, developed at the University of Michigan, could help doctors discover which treatment strategies are most likely to be effective against individual cases of glioma.

12 Jan 2026