Herpes Zoster, also called shingles, is a painful skin rash caused by the varicella-zoster virus, the same virus that causes chickenpox. After a person recovers from chickenpox, the virus remains inactive in the body. Usually the virus does not cause any further problems; however, the virus may re-emerge years later, causing shingles.
In a natural experiment involving 72,920 propensity-matched US adults aged 60 years and older, recombinant shingles vaccination was associated with a 9% lower cardiovascular disease burden over seven years compared with the live attenuated vaccine. Lower burdens of ischemic heart disease and heart failure were seen in both sexes, while ischemic stroke was significantly lower only among men, supporting further clinical trials and mechanistic studies
An analysis in JDDG: Journal der Deutschen Dermatologischen Gesellschaft found that people with eczema (also known as atopic dermatitis) face an elevated risk of developing shingles (or herpes zoster).
Researchers analyzing claims from more than 10 million siblings linked first-born status to higher odds of several neurodevelopmental and allergic diagnoses, while second-born status tracked with substance abuse and gastrointestinal conditions. The observational study identified 150 significant birth-order associations across the phenome, but claims data and residual confounding prevent causal conclusions.
Researchers from the University of Hong Kong (HKUMed), along with Aston Pharmacy School's Professor Ian Chi-Kei Wong, have shown that using paracetamol (acetaminophen) during pregnancy does not increase a child's risk of developing autism spectrum disorder (ASD) or attention‑deficit hyperactivity disorder (ADHD).
For millions worldwide, herpes zoster pain does not end when the rash fades. Postherpetic neuralgia can last for years or even a lifetime, devastating quality of life.
Announcing a new article publication for Zoonoses journal. Varicella-zoster virus (VZV) is a clinically important human neurotropic herpesvirus that causes varicella (chickenpox) as primary infection, typically in children.
A study reveals high-dose influenza vaccines could modestly reduce Alzheimer's risk in older adults, especially women, offering new insights into prevention.
New evidence links viral infections to dementia risk, suggesting vaccines and antiviral therapies may offer preventive pathways against cognitive decline.
A large US claims-based study found that adults aged 65 and older who received a high-dose flu vaccine had a lower observed risk of Alzheimer dementia than those who received a standard-dose vaccine, with the association lasting up to 25 months in per-protocol analyses and 28 months in intention-to-treat analyses. The signal appeared stronger and more sustained in women, though the authors stress that the findings are observational and need confirmation in longer prospective studies.
People with heart disease who received a shingles vaccine had nearly half the rate of serious cardiac events a year later compared with those who did not get the vaccine, according to a study being presented at the American College of Cardiology's Annual Scientific Session (ACC.26).
Research indicates the herpes zoster vaccine may reduce dementia rates by 2%, highlighting its potential role in promoting brain health in aging populations.
Shingles vaccination not only protects against the disease but may also contribute to slower biological aging in older adults, according to a new USC Leonard Davis School of Gerontology study.
Let's be clear: The primary reason to be vaccinated against shingles is that two shots provide at least 90% protection against a painful, blistering disease that a third of Americans will suffer in their lifetimes, one that can cause lingering nerve pain and other nasty long-term consequences.
A large quasi-experimental study in Wales shows that eligibility for shingles vaccination is linked to fewer new mild cognitive impairment diagnoses and lower dementia-related mortality. Benefits appear strongest in women and are observed at multiple stages of the dementia disease course.
In the largest synthesis to date, researchers reviewed 155 studies linking viral infections, including influenza, SARS-CoV-2, HIV, hepatitis C, and shingles, to increased risks of coronary heart disease, stroke, and heart failure. The findings highlight viral infection prevention and vaccination as underappreciated strategies for cardiovascular protection.
In the weeks following a bout of influenza or COVID, the risk of heart attack or stroke may rise dramatically, and chronic infections such as HIV may increase the long-term risk of serious cardiovascular disease events, according to new, independent research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.
Sodium-glucose cotransporter-2 (SGLT-2) inhibitors used to treat type 2 diabetes are associated with an 11% lower risk of autoimmune rheumatic diseases, such as rheumatoid arthritis and lupus, compared with another group of diabetes drugs called sulfonylureas, finds a study from South Korea published by The BMJ today.
A new global systematic literature review and meta-analysis has shown that herpes zoster vaccination, used to prevent shingles, is associated with a statistically significant lower risk of heart attack and stroke.
The American College of Cardiology has issued Concise Clinical Guidance (CCG) recommending vaccines to protect adults with heart disease against respiratory illness, including influenza, COVID-19 and RSV, and other diseases where vaccination is shown to offer cardiovascular protective benefits.
Herpes zoster (HZ) is common in older people, with a lifetime risk of 25%. The main risk factors are advanced age and immunosuppression. People with a rheumatic and musculoskeletal disease have an overall higher risk for shingles.
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