Hormone Replacement Therapy News and Research

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Hormone Replacement Therapy (HRT) sometimes called estrogent replacement therapy or ERT, refers to a woman taking supplements of hormones such as estrogen alone or estrogen with another hormone called progesterone (progestin in its synthetic form). HRT replaces hormones that a woman’s body should be making or used to make.

Ultrasensitive AMH testing offers new insights into midlife ovarian reserve

In women's lifelong health management, the years from 35 to 55 form a critical transition period. During this period, many women face a triple challenge: declining fertility, bothersome perimenopausal symptoms, and delayed or delays in recognizing or confirming menopause.

1 Oct 2026

Study finds oral hormone replacement therapy increases venous thromboembolism risk

Current use of oral menopausal hormone therapy (commonly known as hormone replacement therapy or HRT) is associated with an increased risk of blood clots in legs / lungs regardless of dose or treatment duration, finds a large Danish study published by The BMJ today.

23 Sep 2026

High estrogen alters brain circuit causing temporary memory impairment during pregnancy

Many women usually say the same thing during pregnancy: they walk into a room and forget why, misplace their keys or struggle to follow a conversation.

17 Sep 2026

HRT linked to lower dementia risk, but timing and menopause type matter

In a UK Biobank study of 183,450 postmenopausal women followed for an average of 13.3 years, hormone replacement therapy use was associated with a modestly lower risk of dementia, with stronger associations in women who had surgical menopause or shorter natural estrogen exposure. The relationship also varied by age at HRT initiation, while the observational design means the findings cannot establish that HRT prevents dementia.

27 Aug 2026

Hormone replacement therapy may reduce dementia risk for some women

Hormone replacement therapy (HRT) may reduce the risk of dementia, particularly for certain groups of women - according to a study from the University of East Anglia and the University of Exeter.

26 Aug 2026

Hypothyroidism linked to higher risk of obstructive sleep apnea

According to a study conducted in Brazil by researchers at the Federal University of São Paulo (UNIFESP) with participants from the São Paulo Epidemiological Sleep Study (EPISONO 2018), people with hypothyroidism experience a higher frequency and severity of obstructive sleep apnea (OSA).

5 Aug 2026

Reddit exposes menopause symptoms often missing from medical records

Nearly half the world's population experiences menopause, yet many of its emotional, cognitive and social impacts may never be discussed during medical appointments.

14 Jul 2026

Longer hormone exposure linked to healthier brain aging in women

Research indicates that hormonal therapies and later menopause are associated with increased brain volume and thickness, promoting healthier aging.

26 Jun 2026

Neuroticism and adversity dominate depression and anxiety risk in UK Biobank study

In a UK Biobank study of 87,648 adults followed for 13.7 years, psychosocial factors accounted for the largest estimated population burden of depression and anxiety in both women and men. Neuroticism symptoms, childhood and adult adversity, obesity, chronic inflammation, and some reproductive factors in women were linked to incident mental health outcomes, although the PAF estimates remain theoretical and not proof of causality.

25 Jun 2026

Immunotherapy may help women with early ovarian insufficiency to conceive babies

A pilot study from Karolinska Institutet shows that immunotherapy may enable stimulation of egg maturation in women with autoimmune POI (premature ovarian insufficiency) – a condition that usually leads to infertility.

24 Jun 2026

Longer hormone exposure may increase thyroid cancer risk in women

Longer lifetime exposure to female hormones may increase the risk of thyroid cancer in women, according to a study being presented Saturday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill.

14 Jun 2026

Wearable devices may help detect menstrual health changes earlier

Digital health tools, including wearables, provide critical data on menstrual health, enhancing understanding of hormonal fluctuations and women's well-being.

27 May 2026

Estrogen decline alters brain cell matrix in older females

A largely overlooked space between cells in women's brains may hold the key to understanding memory loss tied to estrogen decline after menopause, reports a new preclinical Northwestern Medicine study.

26 May 2026

Perimenopausal women face higher risk of low heart health

Perimenopausal women were two times more likely to have a low cardiovascular health score compared to women having regular menstrual cycles, according to an analysis of nationwide U.S. data published today in the Journal of the American Heart Association, an open-access, peer-reviewed journal of the American Heart Association.

13 May 2026

Advancing Menopause Care: Non-Hormonal Treatments for Vasomotor Symptoms

Menopause symptoms like hot flushes can be debilitating. Dr. Katie Barber highlights new treatments, including fezolinetant, for improved patient care.

7 May 2026

Traditional plant extract may treat bone and mood disorders in postmenopausal women

Postmenopausal women are at higher risk for both osteoporosis and depression, yet no single treatment effectively addresses both conditions because their shared biological basis remains poorly understood.

25 Apr 2026

Having more children associated with lower stroke risk for women

While some say having lots of kids can make you lose your faculties, a new study suggests otherwise.

20 Apr 2026

Estradiol patches as effective as injections for locally advanced prostate cancer

Hormone patches are as good at controlling locally advanced prostate cancer as the injections typically used to deliver hormone therapy, according to the results of a large clinical trial led by UCL (University College London) researchers.

25 Mar 2026

New method uses biomarkers to determine a person's biological age

Aging is a highly individual process. An international consortium coordinated by researchers in Konstanz has developed a method that uses biomarkers to determine a person's biological age - a valuable tool for research on ageing and the development of new approaches in preventive medicine.

19 Mar 2026

Women face higher liver fibrosis risk from cardiometabolic factors than men

Women with certain cardiometabolic risk factors, including type 2 diabetes and high waist circumference, face a greater increase in risk for liver fibrosis than men with the same risk factors.

9 Mar 2026