Hydroxychloroquine News and Research

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Review highlights traditional Chinese medicine for Chikungunya fever management

Chikungunya fever, caused by Chikungunya virus (CHIKV), has re‑emerged as a major global health threat. The 2025 outbreak in Guangdong, China – the largest local epidemic ever recorded – marks a critical epidemiological turning point.

9 Jul 2026

Feeder-free TIL expansion system makes advanced cancer immunotherapy safer

Conventional TIL therapy, clinically validatedrecently with the U.S. Food and Drug Administration approval of lifileucel for advanced melanoma,stillfaces substantial hurdles.

3 Jul 2026

Widely used pandemic pharmaceuticals harm marine aquatic ecosystems

A new study published in New Contaminants suggests that several drugs widely used during the COVID-19 pandemic can be toxic to marine organisms, even at relatively low concentrations.

2 Jul 2026

Hydroxychloroquine lowers heart risks in skin lupus patients

A study led by investigators from Johns Hopkins Medicine found that some patients with discoid lupus erythematosus - a form of skin lupus commonly diagnosed in young to middle-aged Black women that causes disc-shaped plaques to form on the body - were less likely to experience complications, such as diabetes, hypertension and coronary artery disease if they were prescribed hydroxychloroquine.

26 May 2026

New compounds reduce inflammation without weakening immune defense

Scripps Research scientists have developed a new class of drug compounds that reduce harmful inflammation while leaving the body's ability to fight infections intact-a long-sought goal in treating autoimmune diseases.

6 Apr 2026

Study reveals a new facet of how pancreatic cancer cells regulate autophagy

A feature of pancreatic cancer cells' surroundings determines whether they grow fast or become resistant to chemotherapy, a new study shows.

16 Feb 2026

US cancer institute studying ivermectin’s ‘ability to kill cancer cells’

The National Cancer Institute, the federal research agency charged with leading the war against the nation's second-largest killer, is studying ivermectin as a potential cancer treatment, according to its top official.

10 Feb 2026

Multicenter study supports cautious use of low-dose HCQ in severe COVID-19 cases

This multicenter study investigates the association between hydroxychloroquine (HCQ) dosage and COVID-19 mortality among hospitalized patients in China, aiming to clarify conflicting evidence from prior research.

7 Jul 2025

Deep B cell depletion offers new hope for rheumatologic and musculoskeletal diseases

CD19-CAR T-cell treatment is a novel option of deep B cell depletion with promising results across different rheumatologic and musculoskeletal diseases (RMD).

15 Jun 2025

Why a major hydroxychloroquine study was retracted over statistical misuse

Researchers reanalyzed a retracted HCQ study that claimed over 16,000 COVID-19 deaths and exposed serious methodological flaws, including inappropriate use of effect sizes and lack of dose-specific analysis. The study calls for urgent reform in peer review and greater transparency in scientific publishing.

6 May 2025

Firings at federal health agencies decimate offices that release public records

Public access to government records that document the handling of illnesses, faulty products, and safety lapses at health facilities will slow after mass firings at the federal Department of Health and Human Services swept out staff members responsible for releasing records, according to transparency advocates and health experts.

7 Apr 2025

Study reveals dramatic rise in ivermectin and hydroxychloroquine prescriptions during COVID-19

U.S. outpatient prescriptions for hydroxychloroquine and ivermectin increased 2- to 10-fold above pre-pandemic rates, respectively, to treat COVID-19, despite strong evidence disproving their effectiveness, new UCLA-led research shows.

21 Feb 2025

What RFK Jr. might face in his nomination hearings this week

President Donald Trump has nominated Robert F. Kennedy Jr., an environmental lawyer with no formal medical or public health expertise, as secretary of Health and Human Sciences.

28 Jan 2025

Trump’s picks for top health jobs not just team of rivals but ‘team of opponents’

Many of President-elect Donald Trump's candidates for federal health agencies have promoted policies and goals that put them at odds with one another or with Trump's choice to run the Department of Health and Human Services, Robert F. Kennedy Jr., setting the stage for internal friction over public health initiatives.

17 Dec 2024

Scientists fear what’s next for public health if RFK Jr. is allowed to ‘go wild’

Many scientists at the federal health agencies await the second Donald Trump administration with dread as well as uncertainty over how the president-elect will reconcile starkly different philosophies among the leaders of his team.

14 Nov 2024

Structural biology uncovers the molecular basis of b1 vitamin transport and deficiency

Vitamin B1, also known as thiamine, is essential for the survival of our cells. The human body can't produce it, but we can maintain healthy levels of this vitamin by eating foods like salmon, legumes, and brown rice.

16 Oct 2024

Cardiovascular risks of COVID-19 antivirals

Study reviews cardiovascular side effects linked to antiviral therapies for COVID-19, highlighting the need for careful consideration when prescribing these drugs to high-risk patients.

16 Sep 2024

COVID-19 treatment reporting in U.S. media lacked scientific rigor, study says

A study in JMIR Infodemiology reveals how U.S. media reports on early COVID-19 therapies often lacked scientific evidence and highlighted uncertainties, contributing to misinformation and public mistrust.

2 Sep 2024

Research highlights media misrepresentation of COVID-19 drug efficacy

A new study from researchers at Wake Forest University School of Medicine is shedding light on how scientific evidence and the uncertainty surrounding three unproven therapeutics were portrayed by the U.S. news media during the early days of the COVID-19 pandemic.

30 Aug 2024

Open-ILD: Pioneering stem cell research to combat interstitial lung disease

Imagine a world where breathing is a luxury and a cough marks the sound of an inner battle. Interstitial Lung Disease (ILD), a condition characterised by inflammation and fibrosis, is a major cause of severe respiratory illness and can occur in children.

13 Jun 2024