Hypocaloric Diet News and Research

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Wholegrain rye changes gut bacteria and lowers inflammation in obesity trial

In a 12-week randomized trial, replacing refined wheat with wholegrain rye in a calorie-restricted diet did not produce greater weight loss in adults with overweight or obesity. Wholegrain rye did, however, lower C-reactive protein and alter gut microbiota and short-chain fatty acids in ways that may have positive cardiometabolic implications.

24 Mar 2026

How gut microbiome influences obesity onset differently in men and women

New research being presented at this year's European Congress on Obesity (ECO) in Venice, Italy (12-15 May) identifies changes in the composition of gut bacteria that may play a key role in the onset and development of obesity, with differences in men and women, which might affect the metabolism of different nutrients and therefore the presence of bioactive molecules in the gut that influence the development of metabolic disease.

2 Apr 2024

Study analyzes effects of a calorie-restricted diet on the hippocampus in old rats

A study coordinated by the Institute of Neurosciences of the UAB (INc-UAB) analyzes in old rats the effects of a calorie-restricted diet on the hippocampus, a brain structure that is critical in learning and memory processes.

5 May 2023

How does nutrition affect female fertility?

A new study reviews current evidence supporting the role of nutrition as a modifiable risk factor for female infertility and poor IVF outcomes.

4 Apr 2023

Eating whole grain rye products results in more weight loss than refined wheat diet

Eating whole grain rye products instead of refined wheat alternatives can offer worthwhile health benefits.

12 Oct 2021

Researchers say ‘yes’ to a heavy breakfast to lose weight

There has been some debate on whether or not to pile up on calories at the first meal of the day. According to German researchers, to lose weight, one must eat a healthy and hearty breakfast.

20 Feb 2020

Studies reveal long-term effects of gastric bypass surgery in severely obese teenagers

Gastric bypass surgery helps severely obese teenagers lose weight and keep it off, according to the first long-term follow-up studies of teenagers who had undergone the procedure 5-12 years earlier.

6 Jan 2017

Pioglitazone effective in diabetes patients with NASH

Pioglitazone may halt the progression of nonalcoholic steatohepatitis in patients with prediabetes or Type 2 diabetes, a randomised trial shows.

28 Jun 2016

New study suggests that exercise type may be less important in fight against obesity

Medical experts widely recommended a combined program of diet and fitness to fight obesity. But when it comes to the type of exercise most effective a reducing weight and body mass—strength training, endurance exercise or a combination of both—opinions vary widely on which exercise regimen is best.

27 Apr 2015

Nutrisystem reduces arterial stiffness associated with menopause and obesity

Arturo Figueroa, a researcher in the Florida State University College of Human Sciences, has confirmed with a team of researchers that Nutrisystem, with or without low intense resistance exercise, improves arterial function in obese, postmenopausal women.

9 Jan 2013

Hypocaloric diet may help achieve minimal disease activity in psoriatic arthritis patients

According to a study presented today at EULAR 2012, the Annual Congress of the European League Against Rheumatism, patients with psoriatic arthritis (PsA) who are starting anti-tumour necrosis factor (anti-TNF) treatment and adhere to a hypocaloric diet have a significantly greater chance of achieving minimal disease activity (MDA, an important measure of disease activity) at six months compared to those on a standard diet.

8 Jun 2012

CREB1 molecule activates genes linked to brain longevity

Overeating may cause brain aging while eating less turns on a molecule that helps the brain stay young.

20 Dec 2011

Study: Resveratrol can reduce body fat

For her thesis entitled Conjugated Linoleic Acid and Resveratrol: the effect of these functional ingredients on the metabolism of triglycerides and adiposity, Nutrition and Obesity research team member at the University of the Basque Country, Ms Arrate Lasa, studied the fat-reducing effect of CLA and resveratrol.

4 Mar 2011

Appetite hormones influence 'yo-yo' effect of slimming diets

If you want to lose the kilos you've put on over Christmas, you may be interested in knowing that the hormones related to appetite play an important role in your likelihood of regaining weight after dieting. A new study confirms that people with the highest levels of leptin and lowest levels of ghrelin are more likely to put the centimetres they lost back on again.

13 Jan 2011

VIVUS seeks marketing approval of QNEXA in the EU

VIVUS, Inc. today announced that the company filed a Marketing Authorization Application (MAA) with the European Medicines Agency (EMA) for QNEXA® (phentermine/topiramate) Controlled Release Capsules in the European Union (EU). The proposed indication in the EU is for the treatment of obesity, including weight loss and maintenance of weight loss, and should be used in conjunction with a mildly hypocaloric diet.

20 Dec 2010

VIVUS second-quarter total revenue decreases to $3.9 million

VIVUS, Inc., a biopharmaceutical company dedicated to the development and commercialization of novel therapeutic products, today reported its financial results for the second quarter and six months ended June 30, 2010.

3 Aug 2010

Most breastfeeding mothers do not follow proper diet, study reveals

The study conducted at the University of Granada revealed that 94% of nursing mothers did not follow a proper diet, as they did not consume the recommended diary intake of fat, vitamins A, E and iron, and the intake of proteins was too high. The results obtained will serve to enhance breastfeeding mothers' diet and increase nutritional supply to the newborn.

12 May 2010

Program for defining individualized treatments for each type of obesity

The Danone Institute has provided a fellowship for basic research to Ana Antsn Solanas, a research assistant in the Dietetics and Diet Therapy Unit of the University of Navarra. With the help of this fellowship, the researcher will collaborate in a program for defining individualized treatments for each type of obesity.

27 Jan 2006