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ELRIG announces Drs Stephen Ward and Annarita Miccio as keynote speakers for Cell and Gene Therapy 2026

ELRIG, a not-for-profit, volunteer-led organization dedicated to the global drug discovery community, today announced the keynote speakers for Cell and Gene Therapy 2026. Drs Stephen Ward (Cell and Gene Therapy Catapult) and Annarita Miccio (Imagine Institute) will lead the inaugural two-day event taking place at Hinxton Hall in Cambridge, UK from 9-10 March.

20 Jan 2026

Circadian control of neutrophils limits heart damage after myocardial infarction

Neutrophils cause time-of-day–dependent collateral tissue damage after sterile injury through an intrinsic circadian program. Activating a CXCL12–CXCR4 checkpoint repositions neutrophils, limiting inflammatory injury without impairing antimicrobial defense.

15 Dec 2025

Mass General Brigham launches AI company to enhance clinical trial matching

Mass General Brigham is announcing the spinout of AIwithCare, a company founded by researchers from the health system who developed an artificial intelligence (AI) screening tool that significantly outperformed manual screening for determining a patient's eligibility and enrolling them in a clinical trial.

12 Dec 2025

Study finds no specific harms linked to hydroxyurea exposure during pregnancy

Taking the sickle cell drug hydroxyurea during or shortly before pregnancy does not appear to cause specific issues in newborns, according to the first prospective study of pregnancies involving hydroxyurea exposure.

7 Dec 2025

Challenges and opportunities in delivering gene therapies for sickle cell disease and beta thalassemia

The first study assessing the real-world commercial roll-out of gene therapies for sickle cell disease and beta thalassemia offers lessons learned to inform best practices as manufacturers and medical centers prepare to meet growing demand for gene therapies in the coming years.

7 Dec 2025

New evidence shows hematopoietic cell transplantation offers durable relief for sickle cell disease

Patients who underwent hematopoietic cell transplantation for sickle cell disease saw high rates of survival without disease symptoms and low rates of severe side effects or complications years after their procedure, according to a new study.

7 Dec 2025

Most sickle cell patients face long delays for recommended pain relief, study shows

A new study finds that only one in three patients visiting emergency departments (EDs) for severe pain associated with sickle cell disease received appropriate opioid-based pain-relieving medications within the first hour as recommended by the American Society of Hematology (ASH) and National Heart, Lung, and Blood Institute (NHLBI).

6 Dec 2025

Exa-cel shows complete success in early pediatric trials for sickle cell disease and beta-thalassemia

Preliminary results from two trials of the gene therapy exagamglogene autotemcel (exa-cel) suggest the therapy offers an effective cure for beta-thalassemia and sickle cell disease in children younger than 12.

6 Dec 2025

Study reveals the effectiveness of Painimation in decoding pain for sickle cell patients

Pain is a constant, complex companion that clinicians often struggle to understand and measure for people living with sickle cell disease. Traditional pain scales reduce this deeply personal experience to a single number that is often inaccurate.

13 Nov 2025

Revolutionizing blood diagnostics with real-time QPM technology

Blood tests are among the most common tools in medicine. Scientists are working to make blood cell imaging faster and more intuitive so that doctors can make fast and accurate diagnostic decisions.

24 Oct 2025

Using placental growth factor to predict preeclampsia risk in pregnant women with sickle cell disease

In pregnant women with sickle cell disease, the risk of developing early-onset preeclampsia can be determined by measuring levels of a protein associated with placental function and development.

21 Oct 2025

Inappropriate triage prolongs time to pain medication in vaso-occlusive crisis

Most individuals living with sickle cell disease who presented to the emergency department with a pain crisis, known as vaso-occlusive crisis (VOC), were not triaged appropriately according to established national guidelines, reveals a study published today in Blood Advances.

8 Oct 2025

Active music therapy offers greater pain relief for hospital patients

A new study from University Hospitals Connor Whole Health found that music therapy interventions involving singing, active instrument play, and relaxation/imagery may be more effective for reducing pain intensity than receptive interventions only involving live or recorded music listening among hospitalized patients with moderate-to-severe pain.

25 Sep 2025

Gut microbial imbalance linked to chronic sickle cell disease pain

A research collaboration involving scientists and students at The University of Texas at Dallas has found a clear connection between chronic sickle cell disease pain and the bacteria present in the gastrointestinal tract.

22 Sep 2025

Timely opioid treatment lowers hospitalizations in children with sickle cell disease

A new study has found that prompt administration of opioid pain relief in emergency departments reduces the likelihood of hospitalization for children with sickle cell disease, according to findings published in JAMA Pediatrics.

18 Sep 2025

Dental care gaps affect children with sickle cell disease in Michigan

Children with sickle cell disease are more likely to have dental problems - but fewer than half of those covered by Michigan Medicaid got dental care in 2022, according to a new study.

3 Sep 2025

Gene editing therapy exa-cel improves quality of life in sickle cell disease and beta thalassemia

Treatment with exagamglogene autotemcel (exa-cel) led to robust and sustained improvements in quality of life for patients with severe sickle cell disease (SCD) or transfusion-dependent beta thalassemia, according to two studies published in Blood Advances.

27 Aug 2025

Investigation raises concerns over tooth stem cell banking claims

Parents are spending thousands of pounds to bank stem cells from their children's milk teeth – but the recipient companies' claims about their future medical value are unproven and potentially misleading, reveals an investigation by The BMJ, published today.

21 Aug 2025

New generation of CRISPR shows safer path to treating genetic diseases

A new generation of CRISPR technology developed at UNSW Sydney offers a safer path to treating genetic diseases like Sickle Cell, while also proving beyond doubt that chemical tags on DNA - often thought to be little more than genetic cobwebs - actively silence genes.

17 Aug 2025

Immigrant kids detained in ‘unsafe and unsanitary’ sites as Trump team seeks to end protections

A child developed a rash after he was prevented from changing his underwear for four days. A little boy, bored and overcome with despair, began hitting himself in the head.

30 Jul 2025

I Cell Disease News and Research

ELRIG announces Drs Stephen Ward and Annarita Miccio as keynote speakers for Cell and Gene Therapy 2026

Circadian control of neutrophils limits heart damage after myocardial infarction

Mass General Brigham launches AI company to enhance clinical trial matching

Study finds no specific harms linked to hydroxyurea exposure during pregnancy

Challenges and opportunities in delivering gene therapies for sickle cell disease and beta thalassemia

New evidence shows hematopoietic cell transplantation offers durable relief for sickle cell disease

Most sickle cell patients face long delays for recommended pain relief, study shows

Exa-cel shows complete success in early pediatric trials for sickle cell disease and beta-thalassemia

Study reveals the effectiveness of Painimation in decoding pain for sickle cell patients

Revolutionizing blood diagnostics with real-time QPM technology

Using placental growth factor to predict preeclampsia risk in pregnant women with sickle cell disease

Inappropriate triage prolongs time to pain medication in vaso-occlusive crisis

Active music therapy offers greater pain relief for hospital patients

Gut microbial imbalance linked to chronic sickle cell disease pain

Timely opioid treatment lowers hospitalizations in children with sickle cell disease

Dental care gaps affect children with sickle cell disease in Michigan

Gene editing therapy exa-cel improves quality of life in sickle cell disease and beta thalassemia

Investigation raises concerns over tooth stem cell banking claims

New generation of CRISPR shows safer path to treating genetic diseases

Immigrant kids detained in ‘unsafe and unsanitary’ sites as Trump team seeks to end protections

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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