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The heart effects of antidepressants may depend as much on the patient as the drug

Antidepressants differed in their effects on QTc, with amitriptyline and escitalopram producing small average increases, and the magnitude of changes varying according to individual patient characteristics. The trials did not detect an increase in early major cardiovascular events or non-suicidal sudden death, but they were not large or long enough to rule out rare or later cardiovascular events.

24 Sep 2026

Review highlights how altered metabolism drives kidney cancer growth

Clear cell renal cell carcinoma (ccRCC), the most common subtype of kidney cancer, is increasingly understood as a malignancy shaped by profound changes in cellular metabolism.

24 Sep 2026

Kidney rhythm mismatch linked to dangerous nighttime high blood pressure

Most people's blood pressure falls by 10 to 20 per cent while they sleep, giving the heart and blood vessels a chance to recover. But for some people, that nighttime dip never happens.

24 Sep 2026

Semaglutide’s heart benefits may extend beyond weight loss

Semaglutide is known to reduce the risk of serious heart disease. However, a new study published in the European Heart Journal today (Thursday) suggests that this effect cannot not be entirely explained by patients losing weight on the drug.

23 Sep 2026

Frailty linked to greater cognitive impairment risk in men with chronic kidney disease

New research from the University of Colorado Anschutz Department of Medicine is shedding light on how women and men with chronic kidney disease (CKD) may fare differently as they age and their disease progresses.

23 Sep 2026

UVA study evaluates safety and real-world outcomes of histotripsy

UVA Health researchers have reviewed patient outcomes from a new, noninvasive way to treat liver tumors called histotripsy and concluded that while the procedure was associated with low rates of laboratory toxicity and procedural complications, the findings highlight the need to better define which patients are most likely to benefit.

23 Sep 2026

Cancer incidence rises faster among people with type 2 diabetes

A nationwide study being presented at the Annual Meeting of The European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept 28 – Oct 2) has found that people with type 2 diabetes (T2D) have a higher risk of developing cancer, with cancer incidence rising more among people with T2D than those without diabetes over the past 25 years, largely driven by obesity-related cancers.

22 Sep 2026

C-Path awards $1.7 million to advance five drug development projects

Critical Path Institute (C-Path) today announced that its Translational Therapeutics Accelerator has awarded $1,699,500 through five Bridging Research and Innovation in Drug Development Grants (BRIDGe).

22 Sep 2026

The FFS (Fight Fibrin Sheath) campaign launches to improve patient lives by tackling dialysis catheters' most common dysfunction

An international coalition of vascular access surgeons, nephrologists, researchers and industry partners today launched the Fight Fibrin Sheath (FFS) campaign, a clinician-led action group working collaboratively to advance research, education and innovation relating to fibrin sheath formation, and to improve vascular access outcomes for dialysis patients worldwide.

22 Sep 2026

Roundworm study uncovers cellular effects of kidney disease mutation

A microscopic worm that has no kidneys is helping Rutgers scientists understand a genetic change suspected of causing a serious inherited kidney disease.

21 Sep 2026

Several cups of coffee a day showed no clear diabetes link over 10 years

Researchers followed 1,158 adults in Italy for 10 years, comparing those who drank at least two to three cups of coffee daily with those who drank none. They found no statistically significant difference in new cases of impaired fasting glucose or type 2 diabetes, but the small non-consumer group limits how confidently the study can rule out a difference in risk.

21 Sep 2026

New mRNA vaccine expands flu protection options for older adults

Every fall, millions of Americans heed the call to get their annual flu shot. Getting vaccinated reduces the risk of severe illness, hospitalization, and death from influenza.

20 Sep 2026

Researchers create virtual cells to accelerate drug discovery efforts

Mitochondria - tiny structures that convert nutrients into energy - are often depicted as discrete kidney bean-shaped objects.

18 Sep 2026

High-resolution dataset tracks health impacts of urban heat stress

Heat stress is a leading cause of weather-related deaths and can be especially dangerous in cities where phenomena like urban heat islands drive temperatures higher than surrounding rural areas.

18 Sep 2026

CGM reveals glucose patterns linked to cardiometabolic risk in adults without diabetes

Fasting plasma glucose (FPG) and hemoglobin A1c (HbA1c) are the clinical gold standards for screening for blood sugar levels yet they provide only static snapshots that fail to reflect the highly dynamic and heterogeneous nature of metabolic impairment.

17 Sep 2026

ACC Latin America 2026 studies highlight sex and regional disparities in heart attack care

disparities in ST-segment elevation myocardial infarction (STEMI) management and outcomes across Latin America, focusing on women as a higher risk, yet underrepresented, patient group.

17 Sep 2026

New clinical guidelines standardize kidney replacement therapy in ICU patients

Acute kidney injury (AKI) is a common and severe complication in the intensive care unit (ICU). Due to its high incidence, strong correlation with poor prognosis, and substantial consumption of medical resources, AKI has become one of the central challenges in modern critical care medicine.

17 Sep 2026

GLP-1 drugs and SGLT-2 inhibitors linked to slower kidney decline

The diabetes drugs glucagon-like peptide-1 (GLP-1) receptor agonists and sodium glucose cotransporter 2 (SGLT-2) inhibitor drugs may also help to slow decline in kidney function in people with type 2 diabetes and albuminuria (high protein levels in the urine), finds a large US study published by The BMJ today.

17 Sep 2026

AI-driven health app helps patients achieve better blood pressure control

Incorporating a free smartphone app featuring AI-driven health coaching, blood pressure monitoring, and behavioral incentives into a hospital's existing clinical workflows helps patients make meaningful reductions in blood pressure, findings that suggest that digital apps may offer an effective means of extending care beyond the clinic when incorporated into treatment plans.

16 Sep 2026

Fermented dairy was linked to lower mortality, but the pattern shifted at higher intakes

Analysis of 37,366 US adults found that fermented dairy consumption was associated with lower all-cause and cardiovascular mortality, with consumers showing adjusted hazards 18% and 20% lower, respectively, than non-consumers. Dose-response analyses indicated that the inverse association was concentrated at intakes below about 150 grams per day, while the observational study could not establish causality.

16 Sep 2026