Magnetic Resonance Spectroscopy (MRS) News and Research

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Ketamine's antidepressant effects involve the brain's opioid system

Ketamine is a highly effective, fast-acting antidepressant that works even for patients who have not responded to other medications.

24 Jul 2025

New insight into mechanisms underlying hippocampal atrophy in individuals at risk for psychosis

Dysregulation of the dopamine neurotransmitter system has long been associated with schizophrenia and other forms of psychosis, but recently researchers have begun to examine the glutamate and GABA systems as well.

12 May 2023

Consuming ultra-processed foods is associated with an increased risk of developing non-alcoholic fatty liver disease

Researchers determined the contribution of ultra-processed food intake to the risk of developing NAFLD.

12 May 2023

New evidence explains why thinking hard makes one feel worn out

It's no surprise that hard physical labor wears you out, but what about hard mental labor? Sitting around thinking hard for hours makes one feel worn out, too.

11 Aug 2022

Impaired cardiac metabolism linked to increased risk of fatal arrhythmias or sudden cardiac death

Adults with abnormal heart metabolism are up to three times more likely to experience life-threatening arrhythmias (an irregular heart rhythm), and MRI techniques could be used to detect the condition and predict future sudden cardiac death (SCD), according to a small, but rigorous study led by Johns Hopkins Medicine researchers.

11 Jul 2022

Study links brain temperature with survival after traumatic brain injury

In a recent study published in the journal Brain, researchers explored diurnal, age- and sex-based brain temperature (TBr) variations and evaluated the prognostic importance of TBr mapping for estimating the survival of patients with traumatic brain injuries (TBI).

14 Jun 2022

Study elucidates the mode of action of SGLT2 inhibitors in diabetes

Although SGLT-2 inhibitors are central to the treatment of diabetes, their exact mode of action was hitherto unknown.

8 Feb 2021

Researchers report first spectroscopic imaging-based studies of neurological injury in COVID-19 patients

One of the first spectroscopic imaging-based studies of neurological injury in COVID-19 patients has been reported by researchers at Massachusetts General Hospital (MGH) in the American Journal of Neuroradiology.

19 Nov 2020

Magnetic resonance spectroscopy helps distinguish brain energy molecules

Researchers at Center for BrainHealth®, part of The University of Texas at Dallas, recently examined how cells in the brains of people at risk for developing Alzheimer's disease make and use energy.

24 Sep 2020

MGH researchers identify potential markers of lung cancer

By examining both blood samples and tumor tissues from patients with non-small-cell lung cancer, investigators at Massachusetts General Hospital have identified markers that can distinguish between major subtypes of lung cancer and can accurately identify lung cancer stage.

16 Jul 2019

Compound derived from broccoli sprouts may restore brain chemistry imbalance related to schizophrenia

In a series of recently published studies using animals and people, Johns Hopkins Medicine researchers say they have further characterized a set of chemical imbalances in the brains of people with schizophrenia related to the chemical glutamate.

From Johns Hopkins Medicine 9 May 2019

Researchers measure brain metabolite levels in people with mild memory problems

Using strong and targeted but noninvasive magnets at specific sites in the brains of people with and without mild learning and memory problems, Johns Hopkins researchers report they were able to detect differences in the concentrations of brain chemicals that transmit messages between neurons.

20 Mar 2019

New study aims to identify babies at higher risk of autism and ADHD

London researchers are set to start a three year study aiming to identify babies at higher than average risk of autism spectrum conditions and attention deficit hyperactivity disorder.

27 Sep 2018

Researchers use MR spectroscopy to investigate mechanisms behind targeted treatment for gliomas

Using a novel imaging method, a Massachusetts General Hospital research team is investigating the mechanisms behind a potential targeted treatment for a subtype of the deadly brains tumors called gliomas.

21 May 2018

Measurement of tumor's metabolic activity could help determine prostate cancer prognosis

A new approach to analyzing prostate gland tissue may help address a major challenge in treating prostate cancer - determining which tumors are unlikely to progress and which could be life threatening and require treatment.

27 Mar 2018

Smartphone addiction may be responsible for an imbalance in the brain, study says

A new study presented yesterday at the annual meeting of the Radiological Society of North America (RSNA) identified an imbalance in the brain chemistry of young people who are addicted to smartphones and the internet.

1 Dec 2017

Researchers explore how physical exercise affects brain metabolism

Numerous studies have shown that physical exercise seems beneficial in the prevention of cognitive impairment and dementia in old age. Now researchers at Goethe University Frankfurt have explored in one of the first studies worldwide how exercise affects brain metabolism.

21 Jul 2017

Stuttering linked to changes in speech and language-based brain circuits

Researchers at Children's Hospital Los Angeles have conducted the first study of its kind, using proton magnetic resonance spectroscopy (MRS) to look at brain regions in both adults and children who stutter.

23 Nov 2016

Researchers find strong possibility of preventing, curing neurological conditions using gut bacteria

Could bacteria in your gut be used to cure or prevent neurological conditions such as post-traumatic stress disorder (PTSD), anxiety or even depression? Two researchers sponsored by the Office of Naval Research (ONR) think that's a strong possibility.

26 Apr 2016

Psilocybin administration reduces reaction to social rejection in associated brain areas

Social ties are vital for mental and physical health. However, psychiatric patients in particular frequently encounter social exclusion and rejection. Furthermore, psychiatric patients often react more strongly to social rejection than healthy persons and this can have negative consequences for the development and treatment of psychiatric disorders.

19 Apr 2016