Metabolic Bone Disease News and Research

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Gut microbiome may determine bone loss severity in primary hyperparathyroidism

Primary hyperparathyroidism (PHPT) is a common endocrine disorder characterized by excessive secretion of parathyroid hormone (PTH).

12 Jun 2026

Trial finds prunes do not outperform calcium and vitamin D for male bone density

A one-year randomized trial found that daily prune supplementation did not improve total or lumbar spine bone mineral density in older men susceptible to, or with, osteopenia. Although some bone turnover biomarkers differed between prune and control groups, these changes did not translate into measurable bone density benefits beyond calcium and vitamin D3 supplementation.

11 Jun 2026

Scientists discover how vitamin K pathway regulates bone remodeling

Bone is continuously renewed through a process known as bone remodeling, in which osteoblasts (bone-forming cells) build new bone, while osteoclasts (bone-resorbing cells) remove older mineralized tissue.

21 May 2026

New mouse model reveals key role of osteocytes in osteogenesis imperfecta

Osteogenesis imperfecta (OI) refers to a group of rare genetic bone disorders that results in the formation of fragile bones. In patients with OI, the matrix that makes up the bone has been found to be abnormal, leading to an increased risk of fractures.

13 Aug 2025

Does smoking increase chronic kidney disease risk?

Researchers determine whether smoking increases the risk of chronic kidney disease.

7 Jan 2025

Female ginseng compound holds promise as osteoporosis treatment

With ever-increasing life expectancy comes the challenge of treating age-related disorders such as osteoporosis.

21 Feb 2024

$Study finds fewer fractures in pre-term and low birthweight infants than normal newborns$

Study finds fewer fractures in pre-term and low birthweight infants than normal newborns

Pre-term and low birthweight infants have fewer fractures in childhood than full-term and normal-weight newborns, according to a new a study from the University of Eastern Finland and Kuopio University Hospital.

6 Jun 2023

Scientists reveal molecular mechanisms behind bone loss caused by chronic liver injury

A research team led by Prof. Chen Di from the Shenzhen Institute of Advanced Technology (SIAT) of the Chinese Academy of Sciences along with other collaborators have revealed the molecular mechanisms behind bone loss caused by chronic liver injury.

1 Mar 2022

Professor Cyrus Cooper receives ECTS Steven Boonen Clinical Research award

The International Osteoporosis Foundation is delighted to announce that the European Calcified Tissue Society (ECTS) has presented the prestigious 2021 ECTS Steven Boonen Clinical Research Award to its President, Professor Cyrus Cooper.

7 May 2021

Series of reviews discuss key issues in chronic kidney disease and bone disorders

Metabolic bone disease is a common complication of chronic kidney disease (CKD) and involves a broad spectrum of disorders of mineral metabolism that result in both skeletal and extra-skeletal consequences.

15 Apr 2021

IOF-FFN agreement sets framework for greater collaborative efforts worldwide

The health burden represented by osteoporosis and fragility fractures is growing rapidly at the global level, largely due to ageing demographics.

31 Mar 2020

CT scan of the lumbar spine prior to surgery reveals undiagnosed osteoporosis in many patients

For patients contemplating spinal fusion surgery to alleviate pain, bone health is an important consideration. If a patient is found to have low bone density prior to surgery, it could affect the treatment plan before, during and after the procedure.

13 Mar 2019

Researchers uncover first spontaneous animal model of human hypophosphatasia

A research group led by Professor Hannes Lohi at the University of Helsinki and Folkhälsan Research Center has uncovered a new skeletal disease in dogs.

30 Jan 2019

$GSA endorses Global Call to Action to improve care of people with fragility fractures$

GSA endorses Global Call to Action to improve care of people with fragility fractures

The Gerontological Society of America -- the nation's largest interdisciplinary organization devoted to the field of aging -- has signed on to the Fragility Fracture Network's Global Call to Action to improve the care of people with fragility fractures.

28 Sep 2018

ACR’s updated guideline provides recommendations on treatment of glucocorticoid-induced osteoporosis

The American College of Rheumatology's updated clinical guideline for the prevention and treatment of glucocorticoid-induced osteoporosis is now available online.

7 Jun 2017

New guidelines recommend evaluation of osteoporosis risk for all postmenopausal women

Osteoporosis is preventable and treatable, but only a small proportion of people at risk for fractures are evaluated and treated, according to new osteoporosis guidelines written by an expert panel headed by Loyola Medicine endocrinologist Pauline M. Camacho, MD, FACE.

30 Nov 2016

Leptin gene therapy aids weight loss without significant side effect of bone loss

Delivering the hormone leptin directly to the brain through gene therapy aids weight loss without the significant side effect of bone loss, according to new collaborative research from Oregon State University and University of Florida.

22 Oct 2015

New book provides overview of treatment options for paediatric calcium and bone disorders

Knowledge about paediatric calcium and bone disorders has increased rapidly over the past twenty years. Great advances have been made in the underlying genetic basis for many conditions, in bone density and geometry imaging and in the development of new treatment options, calling for a new edition of 'Calcium and Bone Disorders in Children and Adolescents' which was first published in 2009.

25 Jul 2015

Hospira launches Paricalcitol Injection

Hospira, Inc., the world's leading provider of injectable drugs and infusion technologies, today announced the launch of Paricalcitol Injection, a generic version of AbbVie's Zemplar. Hospira obtained U.S. Food and Drug Administration approval of paricalcitol on Oct. 21 and launched the product Nov. 1.

5 Nov 2014

Study compares efficacy and side effects of popular osteoporosis drugs

A study comparing the efficacy and tolerability of two popular osteoporosis drugs, denosumab and zoledronic acid, found that denosumab had a significantly greater effect on increasing spine bone mineral density and zoledronic acid caused more flulike symptoms.

4 Dec 2013