Methylphenidate News and Research

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Dexamphetamine and methylphenidate work similarly for ADHD but differ in weight effects

A head-to-head trial of ADHD treatments finds dexamphetamine and methylphenidate equally effective, with notable differences in weight management over time.

17 Jul 2026

Scientists identify methylphenidate as an effective tool for combating chronic cancer-related fatigue

A new meta-analysis in the May 2026 issue of JNCCN-Journal of the National Comprehensive Cancer Network provides updated evidence that methylphenidate-type psychostimulants-a class of medication that increases dopamine and norepinephrine availability in the brain-can provide meaningful relief for cancer-related fatigue.

14 May 2026

Childhood ADHD medication shows protective effect against future psychosis

A major new study, led by scientists at University College Dublin and the University of Edinburgh and funded by the St John of God Research Foundation, has found that commonly prescribed attention deficit hyperactivity disorder (ADHD) medication in childhood may lower the long‑term risk of developing serious psychotic disorders, including schizophrenia.

25 Mar 2026

ADHD prescriptions surged during the COVID-19 pandemic

A study reveals COVID-19 reshaped stimulant prescribing patterns in Ontario, highlighting increased ADHD diagnoses and concerns over treatment appropriateness.

11 Mar 2026

Study finds sharp rise in prescriptions for stimulant medications used to treat ADHD

A new Ontario-based study has found a significant rise in prescriptions for stimulant medications used to treat attention-deficit/hyperactivity disorder (ADHD), particularly among adults and females.

11 Dec 2025

Underweight children face higher risk of stopping ADHD medication early

Children who are underweight are more likely to stop taking their ADHD medication within a year. These are the findings of a study conducted at the University of Gothenburg on methylphenidate, a common pharmacological treatment in ADHD.

13 Nov 2025

Systematic analysis reveals psilocybin's impact on obsessive-compulsive behaviors

A systematic review published today in Psychedelics by Mr. James Gattuso and colleagues at the Florey Institute of Neuroscience and Mental Health synthesizes clinical and preclinical evidence on psilocybin's effects on obsessive-compulsive behaviors, revealing consistent therapeutic potential across human patients and validated animal models.

29 Oct 2025

Researchers to analyze shorter ADHD treatment lengths among Hispanic and Black patients

The National Institutes of Health's National Institute on Drug Abuse (NIDA) has awarded $3.7 million to Indiana University researchers to investigate the complex relationship between ADHD medications and serious substance use problems among vulnerable youth and young adults.

3 Oct 2025

ADHD medication lowers risk of substance misuse and accidents

ADHD medications are linked to reduced risks of dangerous outcomes, including substance misuse and criminality, supporting their use in treatment strategies.

18 Aug 2025

Psilocybin rewires the brain for weeks, study finds

Psilocybin induces consistent and sustained changes in brain network connectivity, particularly between the hippocampus and default mode network, as shown using high-resolution fMRI in healthy adults. These neural effects, distinct from those produced by methylphenidate, may underlie the drug’s psychological benefits and were reproducible within individuals over time.

10 Jun 2025

ADHD linked to higher risk of irritable bowel syndrome, global study reveals

A global meta-analysis found that people with ADHD are significantly more likely to have irritable bowel syndrome (IBS), while the overall risk for other intestinal disorders is not increased. The findings highlight the importance of gut-brain interactions in ADHD and call for further research on microbiome-based therapies.

3 Jun 2025

UCLA launches trial of wearable ADHD therapy for children exposed to alcohol in the womb

Researchers at UCLA Health are launching the first clinical trial to test whether a wearable device that delivers gentle nerve stimulation during sleep could ease ADHD symptoms in children with prenatal alcohol exposure.

22 Apr 2025

ADHD medications show minimal impact on heart health in large study

A new study led by the University of Southampton has found that medications for ADHD have overall small effects on blood pressure and heart rate after weeks or a few months of use.

7 Apr 2025

ADHD prescriptions in England surge by 18% since the pandemic

Prescriptions for attention deficit hyperactivity disorder (ADHD) in England have risen 18% year on year since the pandemic.

12 Mar 2025

Can chili peppers improve ADHD symptoms? Scientists explore their gut-brain connection

Chili peppers may influence ADHD symptoms by modulating the gut microbiome, with capsaicin, vitamin C, and omega-3 fatty acids showing potential effects on neurotransmitters and inflammation. However, clinical trials are needed to confirm their efficacy.

20 Feb 2025

Methylphenidate News and Research

Dexamphetamine and methylphenidate work similarly for ADHD but differ in weight effects

Scientists identify methylphenidate as an effective tool for combating chronic cancer-related fatigue

Childhood ADHD medication shows protective effect against future psychosis

ADHD prescriptions surged during the COVID-19 pandemic

Study finds sharp rise in prescriptions for stimulant medications used to treat ADHD

Underweight children face higher risk of stopping ADHD medication early

Systematic analysis reveals psilocybin's impact on obsessive-compulsive behaviors

Researchers to analyze shorter ADHD treatment lengths among Hispanic and Black patients

ADHD medication lowers risk of substance misuse and accidents

Psilocybin rewires the brain for weeks, study finds

ADHD linked to higher risk of irritable bowel syndrome, global study reveals

UCLA launches trial of wearable ADHD therapy for children exposed to alcohol in the womb

ADHD medications show minimal impact on heart health in large study

ADHD prescriptions in England surge by 18% since the pandemic

Can chili peppers improve ADHD symptoms? Scientists explore their gut-brain connection

Comprehensive study highlights effectiveness and limitations of ADHD treatments in adults

High-dose amphetamine use linked to increased risk of psychosis or mania

Current challenges in defining, measuring, and treating MS-related fatigue

Psilocybin reconfigures brain networks, showing potential for lasting therapeutic effects

Pandemic stress leads to surge in ADHD diagnoses and medication use in Finland

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