Neuromodulation News and Research

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Low-power implantable neural chip tracks communication across brain regions

Deep brain stimulation (DBS) is a therapeutic technique that delivers electrical pulses to specific areas of the brain via an implant to modulate neural activity.

23 Oct 2026

UC Davis Health introduces five-day accelerated treatment for severe depression

UC Davis Health has added an accelerated treatment approach for depression at its Advanced Psychiatric Therapeutics (APT) clinic in East Sacramento.

20 Oct 2026

Study links abnormal immature astroglia to lower fluid intelligence in older epilepsy patients

A new USC-led study links abnormal immature astroglia, star-shaped cells that support brain function, to lower fluid intelligence, or the ability to solve new problems, in older adults with epilepsy.

20 Oct 2026

Precise brain circuit targeting may improve depression treatment outcomes

Stimulation of specific brain connections was associated with sustained improvement in people receiving deep brain stimulation (DBS) for treatment-resistant depression, Mount Sinai researchers reported.

14 Oct 2026

Updated tinnitus guideline outlines research-based strategies for patient care

The American Academy of Otolaryngology–Head and Neck Surgery Foundation (AAO-HNSF) today published the Clinical Practice Guideline (CPG): Tinnitus Update in Otolaryngology–Head and Neck Surgery.

12 Oct 2026

New framework maps depression symptoms to unique brain circuits

A research team from the Sant Pau Research Institute (IR Sant Pau) has published a scientific review proposing a paradigm shift in the way depression is understood and studied.

1 Oct 2026

Intracortical microstimulation: Evoking artificial perception and engaging plasticity-based modulation

But creating a long-lasting electronic connection with the brain is complicated. Conventional microwire and silicon electrodes are much stiffer than soft brain tissue.

18 Sep 2026

Salk researchers isolate specific neurons controlling complex social behaviors

Our brains constantly integrate information about both our internal state and our surroundings to determine how we behave.

27 Aug 2026

Vagus nerve stimulation may enhance long-term motor learning

Do you ever feel like sometimes you can master a new dance step almost immediately, while other times you struggle to nail it despite repeated practice? This might be due to skill or effort, but also to something less obvious: whether the brain is in a state that allows learning to take hold.

26 Aug 2026

Multi-target interventions may yield superior outcomes for chronic ankle instability

Ankle sprain is the most prevalent sports-related injury affecting the lower limbs, and up to 70% of individuals with ankle sprain experience persistent symptoms, such as sensorimotor impairment and balance deficits, which may ultimately progress to chronic ankle instability (CAI).

24 Aug 2026

Comprehensive review outlines engineering-driven therapeutic pathways for spinal cord injuries

A comprehensive review published in Engineering outlines multi-disciplinary engineering approaches addressing spinal cord injury (SCI), a debilitating central nervous system disorder triggering permanent sensory, motor, and autonomic dysfunction, and imposing heavy burdens on individuals and societies worldwide.

21 Aug 2026

Intracranial local field potentials offer clues to prolonged disorders of consciousness

Prolonged disorders of consciousness (pDOC) represent states in which patients fail to show reliable evidence of awareness after severe brain injury.

16 Aug 2026

Brain activity before stimulation predicts treatment responses

Brain stimulation can produce very different effects at different moments, even when the stimulus is delivered the exact same way.

14 Aug 2026

NIH grant funds study on stroke-related urinary incontinence

Urinary incontinence is a common but frequently overlooked consequence of stroke. Now, researchers from the Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) at the Keck School of Medicine of USC and Rancho Los Amigos National Rehabilitation Center have received a grant from the National Institutes of Health to investigate the brain changes responsible for these symptoms and develop a more personalized approach to treatment.

27 Jul 2026

Two heart nerve cell types sustain cardiac stability in mice

Researchers identified two major intrinsic cardiac neuron populations in mice: Npy-positive neurons regulate parasympathetic heart rate control and support coronary perfusion, while Ddah1-positive neurons help maintain electrical stability during extreme stress. Removing Npy-positive neurons caused fatal cardiac failure, whereas loss of Ddah1-positive neurons increased susceptibility to malignant arrhythmias and sudden cardiac arrest under stress.

23 Jul 2026

Short-term immunosuppressive therapy briefly restores autism-like brain changes in adult mice

A new mouse study led by UCLA Health suggests that inflammation during pregnancy can trigger autism-like changes in offspring, but also that those brain and behavior effects may be rapidly but temporarily reversible in adulthood with a short-term dose of the immunosuppressive drug rapamycin.

23 Jul 2026

Distributed neural networks make decoding cognition vastly harder than movement

Brain-computer interfaces (BCIs) have made remarkable progress restoring movement and speech in people with paralysis.

21 Jul 2026

Long-term study proves brain stimulation safely restores touch

What if people who have lost the ability to feel their hands could get that sense back - not through a prosthetic glove, but through tiny pulses of electricity delivered directly to the brain?

16 Jul 2026

New framework aligns neural implants with user's needs

Gabriel Lázaro-Muñoz, PhD, JD, and Amanda R. Merner, PhD, of the Health Technology Performance Lab within the Mass General Brigham Neuroscience Institute, are the authors of a paper published in The American Journal of Psychiatry, "Implantable Neuromodulation Devices in Psychiatry: Human Fidelity and Implementation Challenges."

8 Jul 2026

New review shows why antidepressants often fail in Alzheimer’s and Parkinson’s depression

A Molecular Psychiatry review shows that depression in Alzheimer’s and Parkinson’s disease may reflect disease-specific molecular, neurotransmitter, inflammatory, and circuit-level disruptions rather than standard depression biology alone. It argues that broad antidepressants often show limited efficacy in these patients and that future trials should use biomarkers, neuroimaging, and symptom profiling to guide targeted treatments.

7 Jul 2026